Evaluation of a medetomidine-midazolam combination for immobilizing and sedating Japanese monkeys (Macaca fuscata)

Journal of the American Association for Laboratory Animal Science

Volumn 46, Issue 4, 2007, Pages 33-38

  Kimura, Tohru ^a   Koike, Takako ^a   Matsunaga, Tomoko ^a   Sazi, Toshiyuki ^a   Hiroe, Takeshi ^a   Kubota, Mitsuko ^a  

^a NATIONAL INSTITUTES OF NATURAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLASE; ATIPAMEZOLE; KETAMINE; MEDETOMIDINE; MIDAZOLAM; HYPNOTIC SEDATIVE AGENT;

AMYLASE BLOOD LEVEL; ANALGESIA; ANESTHESIA; ANIMAL EXPERIMENT; AROUSAL; ARTICLE; BLOOD EXAMINATION; CHEMICAL ANALYSIS; CONTROLLED STUDY; DEPRESSION; DRUG EFFICACY; DRUG SCREENING; FEMALE; IMMOBILIZATION; MACACA FUSCATA; MALE; MONKEY; MUSCLE RELAXATION; NONHUMAN; PARAMETER; SEDATION; STIMULUS; ANIMAL; ANIMAL DISEASE; COMPARATIVE STUDY; DRUG COMBINATION; ENZYMOLOGY; MACACA; METABOLISM; METHODOLOGY; PHYSIOLOGY; REFERENCE VALUE; SALIVA;

ANIMALIA; JAPANESE MONKEYS; MACACA FUSCATA;

ALPHA-AMYLASE; ANESTHESIA; ANIMALS; DRUG COMBINATIONS; FEMALE; HYPNOTICS AND SEDATIVES; MACACA; MALE; MEDETOMIDINE; MIDAZOLAM; REFERENCE VALUES; SALIVA;

EID: 36048992414     PISSN: 15596109     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Bush BM. 1991. Aspects of interpretation. In: Interpretation of laboratory results for small animal clinicians. Oxford: Blackwell Scientific Publications. p 1-30.
2. Bauer KB, Dom PM, Ramirez AM, O'Flasherty JE. 2004. Preoperative intravenous midazolam: benefits beyond anxiolysis. J Clin Anesth 16:177-183.
3. Capuano SV, Lerche NW, Valverde CR. 1999. Cardiovascular, respiratory, thermoregulatory, sedative, and analgesic effects of intravenous administration of medetomidine in rhesus macaques (Macaca mulatta). Lab Anim Sci 49:537-544.
4. DeLorey TM, Kissin I, Brown P, Brown GB. 1993. Barbiturate-benzodiazepine interactions at the gamma-aminobutyric acid A receptor in rat cerebral cortical synaptonuerosome. Anesth Analg 77:598-605.
5. Hayashi K, Nishimura R, Yamaki A, Kim H, Matsunaga S, Sasaki N. 1995. Cardiopulmonary effects of medetomidine, medetomidine-midazolam and medetomidine-midazolam-atipamezole in dogs. J Vet Med Sci 57:99-104.
6. Hayashi K, Nishimura R, Yamaki A, Matsunaga S, Sasaki N, Takeuchi A. 1994. Comparison of sedative effects induced by medetomidine, medetomidine-midazolam and medetomidine-butorphanol in dogs. J Vet Med Sci 56:951-956.
7. Hayashi K, Nishimura R, Yamaki A, Matsunaga S, Sasaki N, Takeuchi A. 1994. Antagonistic effects of atipamezole on medetomidine-midazolam- induced sedation in dogs. J Vet Med Sci 56:1009-1011.
8. Horne WA. 2001. Primate anesthesia. Vet Clin North Am Exot Anim Prac 4:239-266.
9. Itomoto K, Hikasa Y, Sakonjyu I, Itoh H, Kakuta T, Tanaka K. 2000. Anaesthetic and cardiopulmonary effects of balanced anaesthesia with medetomidine-midazolam and butorphanol in dogs. J Vet Med A Physiol Pathol Clin Med 47:411-420.
10. Itomoto K, Taura Y, Wada N, Takuma T, Une S, Nakaichi M, Hikasa Y. 2002. Quantitative electroencephalography of medetomidine, medetomidine- midazolam and medetomidine-midazolam-butorphanol in dogs. J Vet Med A Physiol Pathol Clin Med 49:169-172.
11. Kain ZN, Hofstadter MB, Mayes LC, Krivutza DM, Alexander G, Wang SM, Reznick JS. 2000. Midazolam: effects on amnesia and anxiety in children. Anesthesiology 93:676-684.
12. Kalema-Zikusoka G, Horne WA, Levine J, Loomis MR. 2003. Comparison of the cardiorespiratory effects of medetomidine-butorphanol-ketamine and medetomidine-butorphanol-midazolam in patas monkeys (Erythrocebus patas). J Zoo Wild Med 34:47-52.
13. Khanderia U, Pandit SK. 1987. Use of midazolam hydrochloride in anesthesia. Clin Pharm 6:533-547.
14. Kimura T. 2006. Personal communication.
15. Kojima K, Nishimura R, Mutoh T, Hong SH, Mochizuki M Sasaki N. 2002. Effects of medetomidine-midazolam, acepromazine-butorphanol, and midazolam-butorphanol on induction dose of thiopental and propofol and on cardiopulmonary changes in dogs. Am J Vet Res 63:1671-1679.
16. Kojima K, Nishimura R, Mutoh T, Takao K, Matsunaga S, Mochizuki M, Sasaki N. 1999. Comparison of sedative effects of medetomidine-midazolam, acepromazine-butorphanol and midazolam-butorphanol in dogs. J Vet Med A 46:141-148.
17. Mutoh T, Nishimura R, Sasaki N. 2002. Effects of medetomidine-midazolam, midazolam-butorphanol, or acepromazine-butorphanol as premedicants for mask induction of anesthesia with sevoflurane in dogs. Am J Vet Res 63:1022-1028.
18. Nater UM, La Marca R, Florin L, Moses A, Langhans W, Koller MM, Ehlert U. 2006. Stress-induced changes in human salivary alpha-amylase activity: associations with adrenergic activity. Psychoneuroendocrinology 31:49-58.
19. Nater UM, Rohleder N, Gaab J, Berger S, Jud A, Kirschbaum C, Ehlert U. 2005. Human salivary alpha-amylase reactivity in a psychosocial stress paradigm. Int J Psychophysiol 55:333-342.
20. Noto Y, Sato T, Kudo M, Kurata K, Hirota K. 2005. The relationship between salivary biomarkers and state-trait anxiety inventory score under mental arithmetic stress: a pilot study. Anesth Analg 101:1873-1876.
21. Pulley AC, Roberts JA, Lerche NW. 2004. Four preanesthetic oral sedation protocols for rhesus macaques (Macaca mulatta). J Zoo Wild Med 35:497-502.
22. Reves JG, Fragen RJ, Vinik HR, Greenblatt DJ. 1985. Midazolam: pharmacology and use. Anesthesiology 62:310-324.
23. Takai N, Yamaguchi M, Aragaki T, Eto K, Uchihashi K, Nishikawa Y. 2007. Gender-specific differences in salivary biomarker respomses to acute psychological stress. Ann N Y Acad Sci 1098:510-515
24. Vaha-Vahe AT. 1990. The clinical effectiveness of atipamezole as a medetomidine antagonist in the dog. J Vet Pharmacol Therap 13:198-205.
25. Vainio O, Vaha-Vahe AT. 1990. Reversal of medetomidine sedation by atipamezole in dogs. J Vet Pharmacol Ther 13:15-22.
26. van Stegeren A, Rohleder N, Everaerd W, Wolf O. 2006. Salivery alpha amylase as marker for adrenergic activity during stress: effect of beta blockade. Psychoneuroendocrinology 31:137-141.
27. Verstegen J, Petcho A. 1993. Medetomidine-butorphanol-midazolam for anaesthesia in dogs and its reversal by atipamezole. Vet Rec 132:353-357.
28. Volger GA. 2006. Anesthesia and analgesia. In: Suckow MA, Weisbroth SH, Franklin CL, editors. The laboratory rat. Burlington: Elsevier Academic Press. p 627-664.
29. Yamaguchi M, Kanemaru M, Kanemori T. Mizuno Y. 2003. Flow-injection-type biosensor system for salivary amylase activities. Biosens Bioelectron 18:835-840.
30. Yamaguchi M, Kanemori T, Kanemaru M, Takai N, Mizuno Y, Yoshida H. 2004. Performance evaluation of salivary amylase activity monitor. Biosens Bioelectron 20:491-497.