Protein concentration and pH affect the apparent P-glycoprotein-ATPase activation kinetics

International Journal of Pharmaceutics

Volumn 346, Issue 1-2, 2008, Pages 169-172

  Heikkinen, Aki T ^a   Mönkkönen, Jukka ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

ABCB1; ATPase activity; Kinetic parameter; MDR1; P glycoprotein

Indexed keywords

ADENOSINE TRIPHOSPHATASE; GLYCOPROTEIN P; MONENSIN; MULTIDRUG RESISTANCE PROTEIN 1; QUINIDINE; VERAPAMIL;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL FRACTIONATION; CELL MEMBRANE; CONCENTRATION (PARAMETERS); ENZYME ACTIVATION; INSECT CELL; KINETICS; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATASES; ANIMALS; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; MONENSIN; P-GLYCOPROTEIN; QUINIDINE; VERAPAMIL;

EID: 36048984732     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.05.063     Document Type: Article

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