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Amarenco P, Bogousslavsky J, Callahan A 3rd, et al., for the SPARCL investigators. High-dose atorvastatin after stroke or transient ischemic attack. N Engl J Med 2006; 355:549-555. This study is the only trial dedicated to secondary stroke prevention with statin therapy, and brings the first evidence for a positive effect of statin in this setting.
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Effects of intense LDL-C reduction in patients with stroke or transient ischemic attack: The Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial
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