Do Sunscreens Increase Risk of Melanoma in Populations Residing at Higher Latitudes?

Annals of Epidemiology

Volumn 17, Issue 12, 2007, Pages 956-963

  Gorham, Edward D ^a   Mohr, Sharif B ^a   Garland, Cedric F ^a   Chaplin, George ^b   Garland, Frank C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Melanoma; Meta analysis; Sunscreens; Ultraviolet A; Ultraviolet B

Indexed keywords

SUNSCREEN;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; MEDICAL RESEARCH; MELANOMA; PRIORITY JOURNAL; RISK ASSESSMENT; SKIN PIGMENTATION; ULTRAVIOLET RADIATION;

CASE-CONTROL STUDIES; GEOGRAPHY; HUMANS; MELANOMA; NEOPLASMS, RADIATION-INDUCED; RISK FACTORS; SKIN NEOPLASMS; SKIN PIGMENTATION; SUNSCREENING AGENTS; ULTRAVIOLET RAYS;

EID: 36048940468     PISSN: 10472797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.annepidem.2007.06.008     Document Type: Article

References (68)

1. Jemal A., Siegel R., Ward E., Murray T., Xu J., and Thun M.J. Cancer statistics, 2007. CA Cancer J Clin 57 (2007) 43-66
2. Ferlay J, Bray F, Pisani P, Parkin D. GLOBOCAN 2002: Cancer Incidence, Mortality and Prevalence Worldwide: IARC CancerBase No. 5. version 2.0 2004 [cited 2006 10 February]; Available from: http://www.dep.iarc.fr.
3. National Cancer Institute. Surveillance, Epidemiology, and End Results Program (SEER) web site. Available at: http://seer.cancer.gov.
4. Cancer Research U. Melanoma Factsheet (2004). http://info.cancerresearchuk.org/cancerstats/types/melanoma/incidence/#source11 Accessed August. 2005
5. Cancer Registry of Norway. Cancer in Norway (2004). http://www.kreftregisteret.no/frame.htm?english.htm Accessed August. 2005
6. Baade P., and Coory M. Trends in melanoma mortality in Australia: 1950-2002 and their implications for melanoma control. Aust N Z J Public Health 29 (2005) 383-386
7. Coory M., Baade P., Aitken J., Smithers M., McLeod G.R., and Ring I. Trends for in situ and invasive melanoma in Queensland, Australia, 1982-2002. Cancer Causes Control 17 (2006) 21-27
8. Lens M.B., and Dawes M. Global perspectives of contemporary epidemiological trends of cutaneous malignant melanoma. Br J Dermatol 150 (2004) 179-185
9. Giles G.G., Armstrong B.K., Burton R.C., Staples M.P., and Thursfield V.J. Has mortality from melanoma stopped rising in Australia? Analysis of trends between 1931 and 1994. BMJ 312 (1996) 1121-1125
10. Czarnecki D., and Meehan C.J. Is the incidence of malignant melanoma decreasing in young Australians?. J Am Acad Dermatol 42 (2000) 672-674
11. Australia Bureau of Statistics. Australian Demographic Statistics (2006). http://www.abs.gov.au [cited May 2007]. Available at:
12. Setlow R., Grist E., Thompson K., and Woodhead A. Wavelengths effective in induction of malignant melanoma. Proc Nat Acad Sci U S A 90 (1993) 6666-6670
13. Garland C., Garland F., and Gorham E. Could sunscreens increase melanoma risk?. Am J Public Health 82 (1992) 614-615
14. Garland C., Garland F., and Gorham E. Rising trends in melanoma: an hypothesis concerning sunscreen effectiveness. Ann Epidemiol 3 (1993) 103-110
15. Garland C.F., Garland F.C., and Gorham E.D. Epidemiologic evidence for different roles of ultraviolet A and B radiation in melanoma mortality rates. Ann Epidemiol 13 (2003) 395-404
16. Adams J.S., Clemens T.L., Parrish J.A., and Holick M.F. Vitamin-D synthesis and metabolism after ultraviolet irradiation of normal and vitamin-D-deficient subjects. N Engl J Med 306 (1982) 722-725
17. Clemens T.L., Adams J.S., Nolan J.M., and Holick M.F. Measurement of circulating vitamin D in man. Clin Chim Acta 121 (1982) 301-308
18. Pfeifer G.P., You Y.H., and Besaratinia A. Mutations induced by ultraviolet light. Mutat Res 571 (2005) 19-31
19. Decraene D., Smaers K., Maes D., Matsui M., Declercq L., and Garmyn M. A low UVB dose, with the potential to trigger a protective p53-dependent gene program, increases the resilience of keratinocytes against future UVB insults. J Invest Dermatol 125 (2005) 1026-1031
20. Bataille V., Bykov V.J., Sasieni P., Harulow S., Cuzick J., and Hemminki K. Photoadaptation to ultraviolet (UV) radiation in vivo: photoproducts in epidermal cells following UVB therapy for psoriasis. Br J Dermatol 143 (2000) 477-483
21. Navaraj A., Mori T., and El-Deiry W.S. Cooperation between BRCA1 and p53 in repair of cyclobutane pyrimidine dimers. Cancer Biol Ther 4 (2005) 1409-1414
22. Diffey B.L., and Farr P.M. UVA filters in sunscreen preparations. Lancet 2 (1989) 170
23. Haywood R., Wardman P., Sanders R., and Linge C. Sunscreens inadequately protect against ultraviolet-A-induced free radicals in skin: implications for skin aging and melanoma?. J Invest Dermatol 121 (2003) 862-868
24. Lund L.P., and Timmins G.S. Melanoma, long wavelength ultraviolet and sunscreens: Controversies and potential resolutions. Pharmacol Ther 114 (2007) 198-207
25. Huncharek M., and Kupelnick B. Use of topical sunscreens and the risk of malignant melanoma: a meta-analysis of 9067 patients from 11 case-control studies. Am J Publ Health 92 (2002) 1173-1177
26. Dennis L.K., Beane Freeman L.E., and VanBeek M.J. Sunscreen use and the risk for melanoma: a quantitative review. Ann Intern Med 139 (2003) 966-978
27. DerSimonian R., and Laird N. Meta-analysis in clinical trials. Control Clin Trials 7 (1986) 177-188
28. Jablonski N.G., and Chaplin G. The evolution of human skin coloration. J Hum Evol 39 (2000) 57-106
29. Chaplin G. Geographic distribution of environmental factors influencing human skin coloration. Am J Phys Anthropol 125 (2004) 292-302
30. Klepp O., and Magnus K. Some environmental and bodily characteristics of melanoma patients. A case-control study. Int J Cancer 23 (1979) 482-486
31. Graham S., Marshall J., Haughey B., Stoll H., Zielezny M., Brasure J., et al. An inquiry into the epidemiology of melanoma. Am J Epidemiol 122 (1985) 606-619
32. Holman C.D., Armstrong B.K., and Heenan P.J. Relationship of cutaneous malignant melanoma to individual sunlight-exposure habits. J Natl Cancer Inst 76 (1986) 403-414
33. Osterlind A., Tucker M.A., Stone B.J., and Jensen O.M. The Danish case-control study of cutaneous malignant melanoma. II. Importance of UV-light exposure. Int J Cancer 42 (1988) 319-324
34. Beitner H., Norell S.E., Ringborg U., Wennersten G., and Mattson B. Malignant melanoma: aetiological importance of individual pigmentation and sun exposure. Br J Dermatol 122 (1990) 43-51
35. Herzfeld P., Fitzgerald E., Hwang S.-A., and Stark A. A case-control study of malignant melanoma of the trunk among white males in upstate New York. Cancer Detection Prev 17 (1993) 601-608
36. Holly E., Aston D., Cress R., Ahn D., and Kristiansen J. Cutaneous melanoma in women: I. Exposure to sunlight, ability to tan, and other risk factors related to ultraviolet light. Am J Epidemiol 141 (1995) 923-933
37. Westerdahl J., Olsson H., Masbach A., et al. Is the use of sunscreens a risk factor for malignant melanoma?. Melanoma Res 5 (1995) 59-65
38. Rodenas J.M., Delgado-Rodriguez M., Herranz M.T., Tercedor J., and Serrano S. Sun exposure, pigmentary traits, and risk of cutaneous malignant melanoma: a case-control study in a Mediterranean population. Cancer Causes Control 7 (1996) 275-283
39. Whiteman D.C., Valery P., McWhirter W., and Green A.C. Risk factors for childhood melanoma in Queensland, Australia. Int J Cancer 70 (1997) 26-31
40. Wolf P., Quehenberger F., Mullegger R., Stranz B., and Kerl H. Phenotypic markers, sunlight-related factors and sunscreen use in patients with cutaneous melanoma: an Austrian case-control study. Melanoma Res 8 (1998) 370-378
41. Autier P., Dore J.F., Cattaruzza M.S., Renard F., Luther H., Gentiloni-Silverj F., et al. Sunscreen use, wearing clothes, and number of nevi in 6- to 7-year-old European children. European Organization for Research and Treatment of Cancer Melanoma Cooperative Group. J Natl Cancer Inst 90 (1998) 1873-1880
42. Espinosa Arranz J., Sanchez Hernandez J.J., Bravo Fernandez P., Gonzalez-Baron M., Zamora Aunon P., Espinosa Arranz E., et al. Cutaneous malignant melanoma and sun exposure in Spain. Melanoma Res 9 (1999) 199-205
43. Naldi L., Gallus S., Imberti G.L., Cainelli T., Negri E., and La Vecchia C. Sunscreens and cutaneous malignant melanoma: an Italian case-control study. Int J Cancer 86 (2000) 879-882
44. Westerdahl J., Ingvar C., Masback A., and Olsson H. Sunscreen use and malignant melanoma. Int J Cancer 87 (2000) 145-150
45. Bakos L., Wagner M., Bakos R.M., Leite C.S., Sperhacke C.L., Dzekaniak K.S., et al. Sunburn, sunscreens, and phenotypes: some risk factors for cutaneous melanoma in southern Brazil. Int J Dermatol 41 (2002) 557-562
46. Youl P., Aitken J., Hayward N., Hogg D., Liu L., Lassam N., et al. Melanoma in adolescents: a case-control study of risk factors in Queensland, Australia. Int J Cancer 98 (2002) 92-98
47. Bevona C., and Sober A.J. Melanoma incidence trends. Dermatol Clin 20 (2002) 589-595 vii
48. Tadokoro T., Yamaguchi Y., Batzer J., Coelho S.G., Zmudzka B.Z., Miller S.A., et al. Mechanisms of skin tanning in different racial/ethnic groups in response to ultraviolet radiation. J Invest Dermatol 124 (2005) 1326-1332
49. Crombie I.K. Variation of melanoma incidence with latitude in North America and Europe. Br J Cancer 40 (1979) 774-781
50. Naylor M.F., Boyd A., Smith D.W., Cameron G.S., Hubbard D., and Neldner K.H. High sun protection factor sunscreens in the suppression of actinic neoplasia. Arch Dermatol 131 (1995) 170-175
51. Thompson S.C., Jolley D., and Marks R. Reduction of solar keratoses by regular sunscreen use. N Engl J Med 329 (1993) 1147-1151
52. Green A., Williams G., Neale R., Hart V., Leslie D., Parsons P., et al. Daily sunscreen application and betacarotene supplementation in prevention of basal-cell and squamous-cell carcinomas of the skin: a randomised controlled trial. Lancet 354 (1999) 723-729
53. Crowson A.N. Basal cell carcinoma: biology, morphology and clinical implications. Mod Pathol 19 Suppl 2 (2006) S127-S147
54. Fukunaga-Kalabis M., Martinez G., Liu Z.J., Kalabis J., Mrass P., Weninger W., et al. CCN3 controls 3D spatial localization of melanocytes in the human skin through DDR1. J Cell Biol 175 (2006) 563-569
55. Hunter D., Colditz D., Stampfer M., et al. Risk factors for basal cell carcinoma in a prospective cohort study of women. Ann Epidemiol 1 (1990) 13-23
56. Matsuoka L., Wortsman J., and Holick M. Chronic sunscreen use decreases the concentration of 25-hydroxyvitamin D: a preliminary study. Arch Dermatol 124 (1988) 1802-1804
57. Maeda T., Chua P.P., Chong M.T., Sim A.B., Nikaido O., and Tron V.A. Nucleotide excision repair genes are upregulated by low-dose artificial ultraviolet B: evidence of a photoprotective SOS response?. J Invest Dermatol 117 (2001) 1490-1497
58. Kaidbey K., Agin P., Sayre R., and Kligman A. Photoprotection by melanin-a comparison of black and caucasian skin. J Am Acad Dermatol 1 (1979) 249-260
59. Garland C.F., Garland F.C., and Gorham E.D. Lack of Efficacy of Common Sunscreens in Melanoma Prevention (1997), Blackwell Science, Malden, MA
60. Moan J., Dahlback A., and Setlow R.B. Epidemiological support for an hypothesis for melanoma induction indicating a role for UVA radiation. Photochem Photobiol 70 (1999) 243-247
61. Eller M., Maeda T., Magnini C., Altwal D., and Gilchrest B. Enhancement of DNA repair in human skin cells by thymidine dinucleotides: Evidence for a p53-mediated mammalian SOS response. Proc Natl Acad Sci U S A 94 (1997) 12627-12632
62. Cormier J.N., Xing Y., Ding M., Lee J.E., Mansfield P.F., Gershenwald J.E., et al. Ethnic differences among patients with cutaneous melanoma. Arch Intern Med 166 (2006) 1907-1914
63. Oikawa A., and Nakayasu M. Stimulation of melanogenesis in cultured melanoma cells by calciferols. FEBS Lett 42 (1974) 32-35
64. Mason R.S., Pryke A.M., Ranson M., Thomas H.E., and Posen S. Human melanoma cells: functional modulation by calciotropic hormones. J Invest Dermatol 90 (1988) 834-840
65. Schlesselman J. Case-Control Studies: Design, Conduct, Analysis (1982), Oxford, New York
66. Holman C., and Armstrong B. Pigmentary traits, ethnic origin, benign nevi and family history as risk factors for cutaneous malignant melanoma. J Natl Cancer Inst 72 (1984) 257-266
67. Columbia University. Center for International Earth Science Information Network (CIESIN) (2006). Available at: www.ciesin.columbia.edu Accessed August 3, 2006
68. Association of Bay Area Governments. Population of San Francisco, 1980 to 2000, by Race and Ethnicity (2006). http://wwwbayareacensuscagov/bayareahtm Accessed September 27