Activation of matrix metalloproteinase-3 is altered at the frog neuromuscular junction following changes in synaptic activity

Developmental Neurobiology

Volumn 67, Issue 11, 2007, Pages 1488-1497

  VanSaun, M ^a,b   Humburg, B C ^a   Arnett, M G ^a   Pence, M ^a   Werle, M J ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Agrin; M2300; Sprouting; Stromelysin; Synaptic plasticity

Indexed keywords

AGRIN; MATRIX METALLOPROTEINASE; STROMELYSIN; TETRODOTOXIN;

ANIMAL TISSUE; ARTICLE; BASEMENT MEMBRANE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; EXTRACELLULAR MATRIX; FROG; IN VIVO STUDY; MUSCLE DENERVATION; NERVE CELL PLASTICITY; NEUROMUSCULAR SYNAPSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; SCHWANN CELL;

ANIMALS; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; FLUORESCENT DYES; MATRIX METALLOPROTEINASE 3; NEUROMUSCULAR JUNCTION; NEURONAL PLASTICITY; RANA PIPIENS; SCHWANN CELLS; SODIUM CHANNEL BLOCKERS; STAINING AND LABELING; SYNAPTIC TRANSMISSION; TETRODOTOXIN;

EID: 35948988822     PISSN: 19328451     EISSN: 1932846X     Source Type: Journal    
DOI: 10.1002/dneu.20523     Document Type: Article

References (29)

1. Allan JA, Hembry RM, Angal S, Reynolds JJ, Murphy G. 1991. Binding of latent and high Mr active forms of stromelysin to collagen is mediated by the C-terminal domain. J Cell Sci 99 (Part 4):789-795.
2. Astrow SH, Qiang H, Ko CP. 1998. Perisynaptic Schwann cells at neuromuscular junctions revealed by a novel monoclonal antibody. J Neurocytol 27:667-681.
3. Becker JW, Marcy AI, Rokosz LL, Axel MG, Burbaum JJ, Fitzgerald PM, Cameron PM, et al. 1995. Stromelysin-1: Three-dimensional structure of the inhibited catalytic domain and of the C-truncated proenzyme. Protein Sci 4:1966-1976.
4. Bickett DM, Green MD, Wagner C, Roth JT, Berman J, McGeehan GM. 1994. A high throughput fluorogenic substrate for stromelysin (MMP-3). Ann NY Acad Sci 732:351-355.
5. Gautam M, Noakes PG, Moscoso L, Rupp F, Scheller RH, Merlie JP, Sanes JR. 1996. Defective neuromuscular synaptogenesis in agrin-deficient mutant mice. Cell 85:525-535.
6. Gomis-Ruth FX, Maskos K, Betz M, Bergner A, Huber R, Suzuki K, Yoshida N, et al. 1997. Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1. Nature 389:77-81.
7. Kim YS, Kim SS, Cho JJ, Choi DH, Hwang O, Shin DH, Chun HS, et al. 2005. Matrix metalloproteinase-3: A novel signaling proteinase from apoptotic neuronal cells that activates microglia. J Neurosci 25:3701-3711.
8. Koirala S, Qiang H, Ko CP. 2000. Reciprocal interactions between perisynaptic Schwann cells and regenerating nerve terminals at the frog neuromuscular junction. J Neurobiol 44:343-60.
9. Kummer TT, Misgeld T, Sanes JR. 2006. Assembly of the postsynaptic membrane at the neuromuscular junction: Paradigm lost. Curr Opin Neurobiol 16:74-82.
10. La Fleur M, Underwood JL, Rappolee DA, Werb Z. 1996. Basement membrane and repair of injury to peripheral nerve: Defining a potential role for macrophages, matrix metalloproteinases, and tissue inhibitor of metalloproteinases-1. J Exp Med 184:2311-2326.
11. McMahan UJ. 1990. The agrin hypothesis. Cold Spring Harb Symp Quant Biol 55:407-418.
12. Meighan SE, Meighan PC, Choudhury P, Davis CJ, Olson ML, Zornes PA, Wright JW, et al. 2006. Effects of extracellular matrix-degrading proteases matrix metalloproteinases 3 and 9 on spatial learning and synaptic plasticity. J Neurochem 96:1227-1241.
13. Muir D, Manthorpe M. 1992. Stromelysin generates a fibronectin fragment that inhibits Schwann cell proliferation. J Cell Biol 116:177-185.
14. Murphy G, Willenbrock F, Crabbe T, O'Shea M, Ward R, Atkinson S, O'Connell J, et al. 1994. Regulation of matrix metalloproteinase activity. Ann NY Acad Sci 732: 31-41.
15. Nagase H, Fields CG, Fields GB. 1994. Design and characterization of a fluorogenic substrate selectively hydrolyzed by stromelysin 1 (matrix metalloproteinase-3). J Biol Chem 269:20952-20957.
16. Nagase H, Visse R, Murphy G. 2006. Structure and function of matrix metalloproteinases and TIMPs. Cardiovasc Res 69:562-573.
17. Noakes PG, Gautam M, Mudd J, Sanes JR, Merlie JP. 1995. Aberrant differentiation of neuromuscular junctions in mice lacking s-laminin/laminin β 2. Nature 374:258-262.
18. Reeves TM, Prins ML, Zhu J, Povlishock JT, Phillips LL. 2003. Matrix metalloproteinase inhibition alters functional and structural correlates of deafferentation-induced sprouting in the dentate gyrus. J Neurosci 23:10182-10189.
19. Reist NE, Magill C, McMahan UJ. 1987. Agrin-like molecules at synaptic sites in normal, denervated, and damaged skeletal muscles. J Cell Biol 105(6, Part 1):2457-2469.
20. Sanes JR, Lichtman JW. 2001. Induction, assembly, maturation and maintenance of a postsynaptic apparatus. Nat Rev Neurosci 2:791-805.
21. Sole S, Petegnief V, Gorina R, Chamorro A, Planas AM. 2004. Activation of matrix metalloproteinase-3 and agrin cleavage in cerebral ischemia/reperfusion. J Neuropathol Exp Neurol 63:338-349.
22. Stanco AM, Werle MJ. 1997. Agrin and acetylcholine receptors are removed from abandoned synaptic sites at reinnervated frog neuromuscular junctions. J Neurobiol 33:999-1018.
23. Stetefeld J, Jenny M, Schulthess T, Landwehr R, Schumacher B, Frank S, Ruegg MA, Engel J, Kammerer RA. 2001. The laminin-binding domain of agrin is structurally related to N-TIMP-1. Nat Struct Biol 8:705-709.
24. VanSaun M, Herrera AA, Werle MJ. 2003. Structural alterations at the neuromuscular junctions of matrix metalloproteinase 3 null mutant mice. J Neurocytol 32:1129-1142.
25. VanSaun M, Werle MJ. 2000. Matrix metalloproteinase-3 removes agrin from synaptic basal lamina. J Neurobiol 43:140-149.
26. Van Wart HE, Birkedal-Hansen H. 1990. The cysteine switch: A principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family. Proc Natl Acad Sci USA 87:5578-5582.
27. Werle MJ, Sojka AM. 1996. Anti-agrin staining is absent at abandoned synaptic sites of frog neuromuscular junctions. J Neurobiol 30:293-302.
28. Wernig A, Herrera AA. 1986. Sprouting and remodelling at the nerve-muscle junction. Prog Neurobiol 27:251-291.
29. Willenbrock F, Murphy G. 1994. Structure-function relationships in the tissue inhibitors of metalloproteinases. Am J Respir Crit Care Med 150(6, Part 2):S165-S170.