Femtosecond laser: A new intradermal DNA delivery method for efficient, long-term gene expression and genetic immunization

FASEB Journal

Volumn 21, Issue 13, 2007, Pages 3522-3533

  Zeira, Evelyne ^a   Manevitch, Alexandra ^a   Manevitch, Zakharia ^a,b   Kedar, Eli ^c   Gropp, Michal ^a   Daudi, Nili ^a   Barsuk, Rimma ^a   Harati, Menahem ^a   Yotvat, Hagit ^a   Troilo, Philip J ^d   Griffiths II, Thomas G ^d   Pacchione, Stephen J ^d   Roden, Dana F ^d   Niu, Zhutian ^d   Nussbaum, Ofer ^e   Zamir, Gideon ^a   Papo, Orit ^a   Hemo, Izhack ^a,b   Lewis, Aaron ^a,b   Galun, Eithan ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c HEBREW UNIVERSITY   (Israel)

^d MERCK RESEARCH LABORATORIES   (United States)

^e XTL Biopharmaceuticals Ltd Israel   (Israel)

Author keywords

Antitumor; Gene delivery; HBV; Vaccination

Indexed keywords

DNA; GAMMA INTERFERON; HEPATITIS B SURFACE ANTIGEN; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INTERLEUKIN 4; RECOMBINANT HEPATITIS B VACCINE; VIRUS DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY TITER; ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENETIC IMMUNIZATION; GENETIC TRANSDUCTION; LASER; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PLASMID; PRIORITY JOURNAL; SAFETY; T LYMPHOCYTE ACTIVATION; TECHNIQUE; TECHNOLOGY; TH1 CELL; TH2 CELL; TISSUE INJURY; VIRUS CELL INTERACTION;

ANIMALS; CELLS, CULTURED; DNA; GENE EXPRESSION; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; IMMUNOGLOBULIN G; INTERFERON TYPE II; INTERLEUKIN-4; LASERS; MICE; MICE, INBRED BALB C; TH1 CELLS; TH2 CELLS; VACCINES, DNA;

HEPATITIS B VIRUS; MUS;

EID: 35948985930     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.06-7528com     Document Type: Article

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