Histatin-derived monomeric and dimeric synthetic peptides show-strong bactericidal activity towards multidrug-resistant Staphylococcus aureus in vivo

Antimicrobial Agents and Chemotherapy

Volumn 51, Issue 9, 2007, Pages 3416-3419

  Welling, Mick M ^a   Brouwer, Carlo P J M ^b   Van 'T Hof, Wim ^c   Veerman, Enno C I ^c   Nieuw Amerongen, Arie V ^c  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b AM Pharma   (Netherlands)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DIMER; HISTATIN 5; HISTATIN DERIVATIVE; MONOMER; PEPTIDE DH5; PEPTIDE DHVAR4; PEPTIDE DHVAR5; PEPTIDE P 113; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; BLADDER; CONTROLLED STUDY; DIMERIZATION; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG LABELING; ISOTOPE LABELING; KIDNEY; LIVER; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MOUSE; MULTIDRUG RESISTANCE; MUSCLE; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; SPLEEN; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION;

ANIMALS; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; METHICILLIN RESISTANCE; MICE; MICROBIAL SENSITIVITY TESTS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; TISSUE DISTRIBUTION;

EID: 35948959330     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00196-07     Document Type: Article

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