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Volumn 7, Issue 6, 2007, Pages 506-509

Hyperimmunoglobulin E syndrome and tyrosine kinase 2 deficiency

Author keywords

Asthma; Atopic dermatitis; Hyperimmunoglobulin E syndrome; Primary immunodeficiency; Tyrosine kinase 2

Indexed keywords

ANTIBIOTIC AGENT; FOCAL ADHESION KINASE 1; GAMMA INTERFERON;

EID: 35948951163     PISSN: 15284050     EISSN: 14736322     Source Type: Journal    
DOI: 10.1097/ACI.0b013e3282f1baea     Document Type: Review
Times cited : (38)

References (15)
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    • Freeman AF, Kleiner DE, Nadiminti H, et al. Causes of death in hyper-IgE syndrome. J Allergy Clin Immunol 2007; 119:1234-1240. This study highlighted the importance of Pseudomonas and Aspergillus infection in cystic lung disease in hyperimmunoglobulin E syndrome.
    • Freeman AF, Kleiner DE, Nadiminti H, et al. Causes of death in hyper-IgE syndrome. J Allergy Clin Immunol 2007; 119:1234-1240. This study highlighted the importance of Pseudomonas and Aspergillus infection in cystic lung disease in hyperimmunoglobulin E syndrome.
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    • Minegishi Y, Saito M, Morio T, et al. Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity. Immunity 2006; 25:745-755. This study provided the first genetic origin of type 2 hyperimmunoglobulin E syndrome. The authors showed that mycobacterial susceptibility is caused by impaired IFN-γ production in response to IL-12, and viral susceptibility is caused by impaired response to type 1 IFN.
    • Minegishi Y, Saito M, Morio T, et al. Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity. Immunity 2006; 25:745-755. This study provided the first genetic origin of type 2 hyperimmunoglobulin E syndrome. The authors showed that mycobacterial susceptibility is caused by impaired IFN-γ production in response to IL-12, and viral susceptibility is caused by impaired response to type 1 IFN.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.