The effect of chronic oxytocin-treatment on the bovine mammary gland immune system

Veterinarni Medicina

Volumn 52, Issue 11, 2007, Pages 475-486

  Werner Misof, C ^a   Pfaffl, M W ^a   Meyer, H H D ^a   Bruckmaier, Rupert M ^b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

Cattle; Mastitis; Oxytocin

Indexed keywords

ANIMALIA; BOS; BOVINAE;

EID: 35848966384     PISSN: 03758427     EISSN: None     Source Type: Journal    
DOI: 10.17221/2059-VETMED     Document Type: Article

References (43)

1. Allen J.C. (1990): Milk synthesis and secretion rates in cows with milk composition changed by oxytocin. Journal of Dairy Science, 73, 975-984
2. Blum J.W., Dosogne H., Hoeben D., Vangroenweghe F., Hammon H.M., Bruckmaier R.M., Burvenich C. (2000): Tumor necrosis factor-alpha and nitrite/nitrate responses during acute mastitis induced by Escherichia coli infection and endotoxin in dairy cows. Domestic Animal Endocrinology, 19, 223-235
3. Bruckmaier R.M. (2003): Chronic oxytocin treatment causes reduced milk ejection in dairy cows. Journal of Dairy Research, 70, 123-126
4. Bruckmaier R.M., Meyer H.H.D. (2005): Immunomediator and milk protein gene expression in mammary tissue during endotoxin-induced mastitis. Livestock Production Science, 98, 81-87
5. Bruckmaier R.M., Schams D., Blum J.W. (1994): Continuously elevated concentrations of oxytocin during milking are necessary for complete milk removal in dairy cows. Journal of Dairy Research, 61, 323-334
6. Bruckmaier R.M., Weiss D., Wiedemann M., Schmitz S., Wendl G. (2004): Changes of physicochemical indicators during mastitis and the effects of milk ejection on their sensitivity. Journal of Dairy Research, 71, 316-321
7. Burvenich C., Paape M.J., Hill A.W., Guidry A.J., Miller R.H., Heyneman R., Kremer W.D.J., Brand A. (1994): Role of the neutrophil leukocyte in the local and systemic reactions during experimentally-induced Escherichia coli mastitis in cows immediately after calving. Veterinary Quarterly, 16, 45-50
8. Fujimoto K. (1995): Freeze-fracture replica electron microscopy combined with SDS digestion for cytochemical labeling of integral membrane proteins. Application to the immunogold labeling of intercellular junctional complexes. Journal of Cell Science, 108, 3443-3449
9. Furuse M., Hirase T., Itoh M., Nagafuchi A., Yonemura S., Tsukita S., Tsukita S. (1993): Occludin: a novel integral membrane protein localizing at tight junctions. Journal of Cell Biology, 123, 1777-1788
10. Guterbock W.M., Van Eenennaam A.L., Anderson R.J., Gardner I.A., Cullor J.S., Holmberg C.A. (1993): Efficacy of intramammary antibiotic therapy for treatment of clinical mastitis caused by environmental pathogens. Journal of Dairy Science, 76, 3437-3444
11. Haskins J., Gu L., Wittchen E.S., Hibbard J., Stevenson B.R. (1998): ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin. The Journal of Cell Biology, 141, 199-208
12. Hillerton J.E., Kliem K.E. (2002): Effective treatment of Streptococcus uberis clinical mastitis to minimize the use of antibiotics. Journal of Dairy Research, 85, 1009-1014
13. Hillerton J.E., Semmens J.E. (1999): Comparison of treatment of mastitis by oxytocin or antibiotics following detection according to changes in milk electrical conductivity prior to visible signs. Journal of Dairy Science, 82, 93-98
14. Itoh M., Furuse M., Morita K., Kubota K., Saitou M., Tsukita S. (1999): Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins. Journal of Cell Biology, 147, 1351-1363
15. Knight C.H., Hirst D., Dewhurst R.J. (1994): Milk accumulation and distribution in the bovine udder during the interval between milkings. Journal of Dairy Research, 61, 167-177
16. Knight C.H., Fitzpatrick J.L., Logue D.N., Platt D.J. (2000): Efficacy of two non-antibiotic therapies, oxytocin and topical liniment, against bovine staphylococcal mastitis. Veterinary Research, 146, 311-316
17. Lefcourt A.M., Akers R.M. (1983): Is oxytocin really necessary for efficient milk removal in dairy cows? Journal of Dairy Science, 66, 2251-2259
18. Linzell J.L. (1967): The effect of very frequent milking and of oxytocin on the yield and composition of milk in fed and fasted goats. Journal of Physiology, London, 190, 333-346
19. Linzell J.L., Peaker M. (1971): Effects of oxytocin and milk removal on milk secretion in goat. Journal of Physiology, London, 216, 717-734
20. Linzell J.L., Peaker M., Taylor J.C. (1975): The effects of prolactin and oxytocin on milk secretion and on the permeability of the mammary epithelium in the rabbit. Journal of Physiology, London, 253, 547-563
21. Macuhova J., Tancin V., Bruckmaier R.M. (2004): Effects of oxytocin administration on oxytocin release and milk ejection. Journal of Dairy Science, 87, 1236-1244
22. Mitchell J.A., Larkin S., Williams T.J. (1995): Cyclooxygenase-2: Regulation and relevance in inflammation. Biochemical Pharmacology, 50, 1535-1542
23. Nguyen D.A., Neville M.C. (1998): Tight junction regulation in the mammary gland. Journal of Mammary Gland Biology and Neoplasia, 3, 233-246
24. Nostrand S.D., Galton D.M., Erb H.N., Bauman D.E. (1991): Effects of daily exogenous oxytocin on lactation milk yield and composition. Journal of Dairy Science, 74, 2119-2127
25. Paape M., Mehrzad J., Zhao X., Detilleux J., Burvenich C. (2002): Defense of the bovine mammary gland by polymorphonuclear neutrophil leukocytes. Journal of Mammary Gland Biology and Neoplasia, 7, 109-121
26. Persson K., Larsson I., Sandgren C.H. (1993): Effects of certain inflammatory mediators on bovine neutrophil migration in vivo and in vitro. Veterinary Immunology and Immunopathology, 37, 99-112
27. PfafflM.W., Wittmann S.L., Meyer H.H., Bruckmaier R.M. (2003): Gene expression of immunologically important factors in blood cells, milk cells, and mammary tissue of cows. Journal of Dairy Science, 86, 538-545
28. Pfeilsticker H.U., Bruckmaier R.M., Blum J.W. (1996): Cisternal milk in the dairy cow during lactation and after preceding teat stimulation. Journal of Dairy Research, 63, 509-515
29. Prgomet C., Sarikaya H., Bruckmaier R.M., PfafflM.W. (2005): Short-term effects on pro-inflammatory cyto kine, lactoferrin and CD14 mRNA expression levels in bovine immunoseparated milk and blood cells treated by LPS. Journal of Veterinary Medicine Series A, Physiology, Pathology, Clinical Medicine, 52, 317-324
30. Riollet C., Rainard P., Poutrel B. (2000): Cells and cytokines in inflammatory secretions of bovine mammary gland. Advances in Experimental Medicine and Biology, 480, 247-258
31. Sapino A., Macri L., Tonda L., Bussolati G. (1993): Oxytocin enhances myoepithelial cell differentiation and proliferation in the mouse mammary gland. Endocrinology, 133, 838-842
32. Sarikaya H., Prgomet C., PfafflM.W., Bruckmaier R.M. (2004): Differentiation of leukocytes in bovine milk. Milchwissenschaft, 59, 586-589
33. Sarikaya H., Schlamberger G., Meyer H.H.D., Bruckmaier R.M. (2006): Leukocyte populations and mRNA expression of inflammatory factors in quarter milk fractions at different somatic cell score levels in dairy cows. Journal of Dairy Science, 89, 2479-2486
34. Schmitz S., PfafflM.W., Meyer H.H., Bruckmaier R.M. (2004): Short-term changes of mRNA expression of various inflammatory factors and milk proteins in mammary tissue during LPS-induced mastitis. Domestic Animal Endocrinology, 26, 111-126
35. Schneeberger E.E., Lynch R.D. (2004): The tight junction: a multifunctional complex. American Journal of Physiology, Cell Physiology, 286, C1213-C1228
36. Sloth K.H.M.N., Friggens N.C., Lovendahl P., Andersen P.H., Jensen J., Ingvartsen K.L. (2003): Potential for improving description of bovine udder health status by combined analysis of milk parameters. Journal of Dairy Science, 86, 1221-1232
37. Sordillo E.M., Streicher K.L. (2002): Mammary gland immunity and mastitis susceptibility. Journal of Mammary Gland Biology and Neoplasia, 7, 135-146
38. Stelwagen K., Davis S.R., Farr V.C., Prosser C.G., Sherlock R.A. (1994): Mammary epithelial cell tight junction integrity and mammary blood flow during an extended milking interval in goats. Journal of Dairy Science, 77, 426-432
39. Stelwagen K., Farr V.C., Davis S.R., Prosser C.G. (1995): Egta-induced disruption of epithelial-cell tight junctions in the lactating caprine mammary-gland. American Journal of Physiology, Regulatory Integrative and Comparative Physiology, 38, R848-R855
40. Stelwagen K., Farr V.C., McFadden H.A., Prosser C.G., Davis S.R. (1997): Time course of milk accumulationinduced opening of mammary tight junctions, and blood clearance of milk components. American Journal of Physiology, Regulatory Integrative and Comparative Physiology, 42, R379-R386
41. Wittchen E.S., Haskins J., Stevenson B.R. (1999): Protein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3. Journal of Biological Chemistry, 274, 35179-35185
42. Wittmann S.L., PfafflM.W., Meyer H.H.D., Bruckmaier R.M. (2002): 5-Lipoxygenase, cyclooxygenase-2 and tumor necrosis factor alpha gene expression in somatic milk cells. Milchwissenschaft, 57, 63-66
43. Wong V., Gumbiner B.M. (1997): A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrier. Journal of Cell Biology, 136, 399-409