Relationship between 99mTc-GSA scintigraphic indices of liver function reserve and portal circulation in patients with chronic liver disease

Annals of Nuclear Medicine

Volumn 21, Issue 5, 2007, Pages 245-249

  Osada, Hisato ^a   Honda, Norinari ^a   Takahashi, Takeo ^a   Oku, Shinya ^a   Abe, Atsushi ^a   Watanabe, Wataru ^a   Okada, Takemichi ^a   Ohno, Hitoshi ^a   Hondo, Mikito ^a   Nishimura, Keiichiro ^a  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

99mTc GSA; Chronic liver disease; Portal circulation; Portal hypertension; Varix

Indexed keywords

ALCOHOL; BIOLOGICAL MARKER; GALACTOSYL HUMAN SERUM ALBUMIN TECHNETIUM 99M; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; MACROSALB TC 99M; PENTETATE TECHNETIUM TC 99M; TECHNETIUM TC 99M DTPA GALACTOSYL HUMAN SERUM ALBUMIN; TECHNETIUM TC 99M DTPA-GALACTOSYL-HUMAN SERUM ALBUMIN;

ADULT; AGED; ARTICLE; CHRONIC LIVER DISEASE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; ESOPHAGOGASTRODUODENOSCOPY; FEMALE; HUMAN; KRUSKAL WALLIS TEST; LIVER ARTERIOGRAPHY; LIVER FUNCTION; MAJOR CLINICAL STUDY; MALE; MAXIMUM ALLOWABLE CONCENTRATION; PLASMA CLEARANCE; PORTAL VEIN BLOOD FLOW; PORTOSYSTEMIC ANASTOMOSIS; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; RETROSPECTIVE STUDY; SCINTIGRAPHY; VARICOSIS; ANGIOGRAPHY; CHEMISTRY; ENDOSCOPY; INSTRUMENTATION; LABORATORY DIAGNOSIS; LIVER DISEASE; LIVER FUNCTION TEST; METHODOLOGY; MIDDLE AGED; ROC CURVE; SCINTISCANNING;

AGED; ANGIOGRAPHY; ENDOSCOPY; FALSE POSITIVE REACTIONS; HUMANS; LIVER DISEASES; LIVER FUNCTION TESTS; MIDDLE AGED; PORTASYSTEMIC SHUNT, SURGICAL; RADIONUCLIDE IMAGING; RADIOPHARMACEUTICALS; ROC CURVE; TECHNETIUM TC 99M AGGREGATED ALBUMIN; TECHNETIUM TC 99M PENTETATE;

EID: 35848961428     PISSN: 09147187     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12149-007-0016-0     Document Type: Article

References (18)

1. K Torizuka SK Ha-Kawa M Kudo S Kitagawa Y Kubota Y Tanaka 1992 Phase II clinical study on 99mTc-GSA, a new agent for functional imaging of the liver (in Japanese) Kaku Igaku (Jpn J Nucl Med) 29 85 95
2. YK Kim H Nakano M Yamaguchi K Kumada S Takeuchi N Kitamura 1997 Prediction of postoperative decompensated liver function by technetium-99m galactosyl-human serum albumin liver scintigraphy in patients with hepatocellular carcinoma complicating chronic liver disease Br J Surg 84 793 6
3. H Nakano K Yoshida S Takeuchi K Kumada M Yamaguchi D Jaeck 1999 Liver scintigraphy is useful for selecting candidates for preoperative transarterial chemoembolization among patients with hepatocellular carcinoma and chronic liver disease Am J Surg 178 385 9
4. N Sasaki S Shiomi Y Iwata S Nishiguchi T Kuroki J Kawabe 1999 Clinical usefulness of scintigraphy with 99mTc-galactosyl-human serum albumin for prognosis of cirrhosis of the liver J Nucl Med 40 1652 6
5. K Fukunaga T Todoroki Y Takada M Otsuka T Kawamoto K Fukao 1999 Hepatic functional reserve in patients with biliary malignancies: an assessment by technetium 99m galactosyl human serum albumin hepatic scintigraphy Int Surg 84 199 203
6. M Kondo 2001 Usefulness of 99mTc-GSA scintigraphy for estimation of residual hepatic functions and postoperative changes of HH15 and LHL15 (in Japanese) Kaku Igaku (Jpn J Nucl Med) 38 191 200
7. T Iguchi S Sato Y Kouno Y Okumura S Akaki T Tsuda 2003 Comparison of Tc-99m-GSA scintigraphy with hepatic fibrosis and regeneration in patients with hepatectomy Ann Nucl Med 17 227 33
8. The Japan Society for Portal Hypertention and Esophago-Gastric Varices. The general rules for study of portal hypertention, 1st edition. Tokyo: Kanehara, 1996. 58-61
9. K Koizumi G Uchiyama T Arai T Ainoda Y Yoda 1992 A new liver functional study using Tc-99m DTPA-galactosyl human serum albumin: evaluation of the validity of several functional parameters Ann Nucl Med 6 83 7
10. SK Ha-Kawa Y Suga K Ikeda K Nagata T Murata Y Tanaka 1993 Usefulness of blood disappearance corrected hepatic uptake ratio (LHL/HH) as a hepatic functional index using 99mTc-galactosyl serum albumin (in Japanese) Kaku Igaku (Jpn J Nucl Med) 30 1333 9
11. J Hashimoto A Ishibashi T Kajitani T Kurihara Y Fukamizu T Kitahora 1994 Quantitative evaluation of liver function with 99mTc-GSA scintigraphy using extraction index (in Japanese) Kaku Igaku (Jpn J Nucl Med) 31 1093 100
12. K Nakajima K Kinuya Y Mizutani EH Hwang T Michigishi N Tonami 1999 Simple scintigraphic parameters with Tc-99m galactosyl human serum albumin for clinical staging of chronic hepatocellular dysfunction Ann Nucl Med 13 5 11
13. SK Ha-Kawa Y Tanaka 1991 A quantitative model of technetium-99m-DTPA- galactosyl-HSA for the assessment of hepatic blood flow and hepatic binding receptor J Nucl Med 32 2233 40
14. K Murase T Tsuda T Mochizuki J Ikezoe 1998 A simplified method for the quantitative analysis of 99Tc(m)-GSA liver scintigraphy using spectral analysis Nucl Med Commun 19 219 27
15. S Shiomi T Kuroki N Ikeoka K Fukuda T Ueda K Kobayashi 1993 Evaluation of clinical usefulness of 99mTc-GSA, a functional hepatic imaging agent-correlation with per-rectal portal scintigraphy (in Japanese) Kaku Igaku (Jpn J Nucl Med) 30 735 41
16. S Endo K Ohashi A Fukui A Nikai S Maeyama 2000 Tc-99m GSA scintigraphy for evaluation of liver function: correlations with histological grading and staging (new Inuyama clssificaton) Jpn J Med Imaging 19 259 67
17. S Tomiguchi T Kira Y Oyama M Nabeshima R Nakashima A Tsuji 1995 Correlation of Tc-99m GSA hepatic studies with biopsies in patients with chronic active hepatitis Clin Nucl Med 20 717 20
18. T Kira S Tomiguchi M Takahashi S Yoshimatsu K Sagara R Kurano 1999 Correlation of 99mTc-GSA hepatic scintigraphy with liver biopsies in patients with chronic active hepatitis type C Radiat Med 17 125 30