Metabolomic investigation of CLN6 neuronal ceroid lipofuscinosis in affected South Hampshire sheep

Journal of Neuroscience Research

Volumn 85, Issue 15, 2007, Pages 3494-3504

  Pears, Michael R ^a   Salek, Reza M ^a   Palmer, David N ^b   Kay, Graham W ^b   Mortishire Smith, Russell J ^c   Griffin, Julian L ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b LINCOLN UNIVERSITY   (New Zealand)

^c JOHNSON AND JOHNSON   (United States)

Author keywords

Batten disease; Brain; CLN6; CSF; Glutamate glutamine cycling; Metabonomics; Multivariate statistical analysis; Neurodegenerative disease

Indexed keywords

4 AMINOBUTYRIC ACID; ACETIC ACID; ASPARTIC ACID; GLUTAMIC ACID; GLUTAMINE; INOSITOL; N ACETYLASPARTIC ACID; SUCCINIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CEREBELLUM; CEREBROSPINAL FLUID; CLN6 GENE; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE COURSE; FRONTAL LOBE; GAS CHROMATOGRAPHY; GENE; HETEROZYGOSITY; MASS SPECTROMETRY; MULTIVARIATE ANALYSIS; NERVE DEGENERATION; NEURONAL CEROID LIPOFUSCINOSIS; NONHUMAN; OCCIPITAL LOBE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SHEEP;

ANIMALS; BRAIN; DISEASE PROGRESSION; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; MAGNETIC RESONANCE SPECTROSCOPY; MEMBRANE PROTEINS; NEURONAL CEROID-LIPOFUSCINOSES; NEUROTRANSMITTER AGENTS; SHEEP; SHEEP DISEASES;

EID: 35848957261     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21343     Document Type: Conference Paper

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