-
1
-
-
0036489213
-
The evolving role of information technology in the drug discovery process
-
Augen, J. 2002. The evolving role of information technology in the drug discovery process. Drug Discovery Today 7(5): 315-23.
-
(2002)
Drug Discovery Today
, vol.7
, Issue.5
, pp. 315-323
-
-
Augen, J.1
-
3
-
-
0037449244
-
Genetic and Nelder-Mead algorithms hybridized for a more accurate global optimization of continuous multiminima functions
-
Chelouah, R., and P. Siarry. 2003. Genetic and Nelder-Mead algorithms hybridized for a more accurate global optimization of continuous multiminima functions. European Journal of Operational Research 148: 335-348.
-
(2003)
European Journal of Operational Research
, vol.148
, pp. 335-348
-
-
Chelouah, R.1
Siarry, P.2
-
4
-
-
0000808501
-
Fuzzy techniques of pattern recognition in risk and claim classification
-
Derrig, R. A., and K. M. Ostaszewski. 1995. Fuzzy techniques of pattern recognition in risk and claim classification. Journal of Risk and Insurance 62: 447-482.
-
(1995)
Journal of Risk and Insurance
, vol.62
, pp. 447-482
-
-
Derrig, R.A.1
Ostaszewski, K.M.2
-
5
-
-
26444522301
-
Biomimetic in silico devices. Computational Methods in Systems Biology
-
Available via, accessed April 8, 2006
-
Hunt, C. A., G. E. P. Ropella, M. S. Roberts, and L. Yan. 2004. Biomimetic in silico devices. Computational Methods in Systems Biology. Lecture Notes in Bioinformatics 3082: 34-42. Available via 〈http://biosystems.ucsf.edu/Research/RecentPapers.html〉 [accessed April 8, 2006].
-
(2004)
Lecture Notes in Bioinformatics
, vol.3082
, pp. 34-42
-
-
Hunt, C.A.1
Ropella, G.E.P.2
Roberts, M.S.3
Yan, L.4
-
6
-
-
46149112565
-
-
Johns Hopkins Pathology. 2006. Gallbladder & bile duct cancer. Anatomy and physiology of the gallbladder and bile ducts. Available via 〈http://pathology2.jhu.edu/gbbd/anatphys.cfm〉 [accessed April 8, 2006].
-
Johns Hopkins Pathology. 2006. Gallbladder & bile duct cancer. Anatomy and physiology of the gallbladder and bile ducts. Available via 〈http://pathology2.jhu.edu/gbbd/anatphys.cfm〉 [accessed April 8, 2006].
-
-
-
-
7
-
-
0032815251
-
Biliary excretion in primary rat hepatocytes cultured in a collagen-sandwich configuration
-
Liu, X., E. L. LeCluyse, K. R. Brouwer, L-S. L. Gan, LeMasters, J. J. Stieger, B. P. J. Meier, and K. L. R. Brouwer. 1999a. Biliary excretion in primary rat hepatocytes cultured in a collagen-sandwich configuration. American Journal of Physiology 277: G12-G21.
-
(1999)
American Journal of Physiology
, vol.277
-
-
Liu, X.1
LeCluyse, E.L.2
Brouwer, K.R.3
Gan, L.-S.L.4
LeMasters5
Stieger, J.J.6
Meier, B.P.J.7
Brouwer, K.L.R.8
-
8
-
-
0033017134
-
Correlation of biliary excretion in sandwich-cultured rat hepatocytes and in vivo in rats
-
Liu, X., J. P. Chism, E. L. LeCluyse, K. R. Brouwer, and K. L. R. Brouwer. 1999b. Correlation of biliary excretion in sandwich-cultured rat hepatocytes and in vivo in rats. Drug Metabolism and Disposition 27: 637-644.
-
(1999)
Drug Metabolism and Disposition
, vol.27
, pp. 637-644
-
-
Liu, X.1
Chism, J.P.2
LeCluyse, E.L.3
Brouwer, K.R.4
Brouwer, K.L.R.5
-
9
-
-
27644466938
-
Studies of intestinal drug transport using an in silico epithelio-mimetic device
-
Liu, Y., and C.A. Hunt 2005. Studies of intestinal drug transport using an in silico epithelio-mimetic device. Biosystems 82(2): 154-167.
-
(2005)
Biosystems
, vol.82
, Issue.2
, pp. 154-167
-
-
Liu, Y.1
Hunt, C.A.2
-
10
-
-
33644904332
-
Mechanistic study of the interplay of intestinal transport and metabolism using the synthetic modeling method
-
Liu, Y., and Hunt, C. A. 2006. Mechanistic study of the interplay of intestinal transport and metabolism using the synthetic modeling method. Pharmaceutical Research 23(3): 493-505.
-
(2006)
Pharmaceutical Research
, vol.23
, Issue.3
, pp. 493-505
-
-
Liu, Y.1
Hunt, C.A.2
-
11
-
-
0036931467
-
Globalized Nelder-Mead method for engineering optimization
-
Civil-Comp Press, Edinburgh, Scotland
-
Luersen, M. A., and R.L. Riche. 2002. Globalized Nelder-Mead method for engineering optimization. In Proceedings of the Third International Conference on Engineering Computational Technology (Stirling, Scotland, Sept 4-6), 165-166. Civil-Comp Press, Edinburgh, Scotland.
-
(2002)
Proceedings of the Third International Conference on Engineering Computational Technology (Stirling, Scotland, Sept 4-6)
, pp. 165-166
-
-
Luersen, M.A.1
Riche, R.L.2
-
12
-
-
0032251894
-
Convergence properties of the Nelder-Mead simplex method in low dimensions
-
Lagarias, J. C., J. A. Reeds, M. H. Wright, and P. E. Wright. 1998. Convergence properties of the Nelder-Mead simplex method in low dimensions. SIAM Journal on Optimization 9(1): 112-147.
-
(1998)
SIAM Journal on Optimization
, vol.9
, Issue.1
, pp. 112-147
-
-
Lagarias, J.C.1
Reeds, J.A.2
Wright, M.H.3
Wright, P.E.4
-
13
-
-
0000238336
-
A simplex method for function minimization
-
Nelder, J. A., and R. Mead. 1965. A simplex method for function minimization. Computer Journal 7:308-313.
-
(1965)
Computer Journal
, vol.7
, pp. 308-313
-
-
Nelder, J.A.1
Mead, R.2
-
14
-
-
84873002330
-
Adaptive extensions of the Nelder and Mead simplex method for optimization of stochastic simulation models
-
Econometric Institute, Erasmus University, Rotterdam
-
Neddermeijer, H. G., G. J. Oortmarssen, N. Piersma, and R. Dekker. 2000. Adaptive extensions of the Nelder and Mead simplex method for optimization of stochastic simulation models. Econometric Institute Report 199. Econometric Institute, Erasmus University, Rotterdam.
-
(2000)
Econometric Institute Report
, vol.199
-
-
Neddermeijer, H.G.1
Oortmarssen, G.J.2
Piersma, N.3
Dekker, R.4
-
17
-
-
46149119848
-
-
Ropella, G. E., C. A. Hunt, and D. A. Nag. 2005a. Using heuristic models to bridge the gap between analytic and experimental models in biology. In Proceedings of the 2005 Agent-Directed Simulation Symposium (San Diego, CA, Apr 2-8), Simulation Series 37, no. 2, ed. L. Yilmaz, SCS Press, San Diego, CA, 182-190.
-
Ropella, G. E., C. A. Hunt, and D. A. Nag. 2005a. Using heuristic models to bridge the gap between analytic and experimental models in biology. In Proceedings of the 2005 Agent-Directed Simulation Symposium (San Diego, CA, Apr 2-8), Simulation Series vol. 37, no. 2, ed. L. Yilmaz, SCS Press, San Diego, CA, 182-190.
-
-
-
-
18
-
-
84867359313
-
Methodological considerations of heuristic modeling of biological systems
-
FL, July 10-13
-
Ropella, G. E., C. A. Hunt, and S. Sheikh-Bahaei. 2005b. Methodological considerations of heuristic modeling of biological systems. The 9th World Multi-Conference on Systemics, Cybernetics and Informatics (Orlando, FL, July 10-13).
-
(2005)
The 9th World Multi-Conference on Systemics, Cybernetics and Informatics (Orlando
-
-
Ropella, G.E.1
Hunt, C.A.2
Sheikh-Bahaei, S.3
-
20
-
-
46149095713
-
-
Sheikh-Bahaei, S., G. E. P. Ropella, and C. A. Hunt. 2005. Agent-based simulation of in vitro hepatic drug metabolism: in silico hepatic intrinsic clearance. In Proceedings of the 2005 Agent-Directed Simulation Symposium (San Diego, CA, Apr 2-8), Simulation Series 37(2), ed. L. Yilmaz, SCS Press, San Diego, CA, 171-6.
-
Sheikh-Bahaei, S., G. E. P. Ropella, and C. A. Hunt. 2005. Agent-based simulation of in vitro hepatic drug metabolism: in silico hepatic intrinsic clearance. In Proceedings of the 2005 Agent-Directed Simulation Symposium (San Diego, CA, Apr 2-8), Simulation Series vol. 37(2), ed. L. Yilmaz, SCS Press, San Diego, CA, 171-6.
-
-
-
-
21
-
-
46149112736
-
-
Sheikh-Bahaei, S., G. E. P. Ropella, and C. A. Hunt. 2006. In silico hepatocyte: agent-based modeling of the biliary excretion of drugs in vitro. In Proceedings of the 2006 Agent-Directed Simulation Symposium (Huntsville, AL, Apr 3-9), Simulation Series, ed. L. Yilmaz, et al., SCS Press, San Diego, CA (ISBN 1-56555-303-9), 157-163.
-
Sheikh-Bahaei, S., G. E. P. Ropella, and C. A. Hunt. 2006. In silico hepatocyte: agent-based modeling of the biliary excretion of drugs in vitro. In Proceedings of the 2006 Agent-Directed Simulation Symposium (Huntsville, AL, Apr 3-9), Simulation Series, ed. L. Yilmaz, et al., SCS Press, San Diego, CA (ISBN 1-56555-303-9), 157-163.
-
-
-
-
22
-
-
1542400036
-
A multi-algorithm, multi-timescale method for cell simulation
-
Takahashi, K., K. Kaizu, B. Hu, and M. Tomita. 2004. A multi-algorithm, multi-timescale method for cell simulation. Bioinformatics 20(4):538-546.
-
(2004)
Bioinformatics
, vol.20
, Issue.4
, pp. 538-546
-
-
Takahashi, K.1
Kaizu, K.2
Hu, B.3
Tomita, M.4
-
23
-
-
0037249266
-
Estimating parameters of a microsimulation model for breast cancer screening using the score function method
-
Tan, S. Y. G. L., G. J. Oortmarssen, and N. Piersma. 2003. Estimating parameters of a microsimulation model for breast cancer screening using the score function method. Annals of Operations Research 119(1-4): 43-61.
-
(2003)
Annals of Operations Research
, vol.119
, Issue.1-4
, pp. 43-61
-
-
Tan, S.Y.G.L.1
Oortmarssen, G.J.2
Piersma, N.3
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