Pancreatitis in primary hyperparathyroidism-related hypercalcaemia is not associated with mutations in the CASR gene

Experimental and Clinical Endocrinology and Diabetes

Volumn 115, Issue 8, 2007, Pages 527-529

  Felderbauer, P ^a   Karakas, E ^b   Fendrich, V ^b   Bulut, K ^a   Werner, I ^a   Dekomien, G ^c   Klein, W ^c   Bartsch, D ^d   Schmidt, W E ^a  

^a ST JOSEF HOSPITAL   (Germany)

^b UNIVERSITY HOSPITAL MARBURG   (Germany)

^c RUHR UNIVERSITY BOCHUM   (Germany)

^d OWL University   (Germany)

Author keywords

CASR; Hypercalcemia; Hyperparathyroidism; Pancreatitis

Indexed keywords

CALCIUM; CALCIUM SENSING RECEPTOR;

ADULT; ARTICLE; CALCIUM HOMEOSTASIS; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; GENE MUTATION; HETEROZYGOSITY; HUMAN; HYPERCALCEMIA; HYPERTHYROIDISM; MAJOR CLINICAL STUDY; MALE; PANCREATITIS; PARATHYROID CELL; PRIORITY JOURNAL; PROSPECTIVE STUDY; SINGLE STRAND CONFORMATION POLYMORPHISM;

FEMALE; HUMANS; HYPERCALCEMIA; HYPERPARATHYROIDISM, PRIMARY; MALE; MIDDLE AGED; MUTATION; PANCREATITIS; RECEPTORS, CALCIUM-SENSING; RETROSPECTIVE STUDIES;

EID: 35848932528     PISSN: 09477349     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-981455     Document Type: Article

References (25)

1. Agarwal A, George RK, Gupta SK, Mishra SK. Pancreatitis in patients with primary hyperparathyroidism. Indian J Gastroenterol 2003; 22: 224-225
2. Bess MA, Edis AJ, Heerden JA van. Hyperparathyroidism and pancreatitis. Chance or a causal association? Jama 1980; 243: 246-247
3. Brown EM, Gamba G, Riccardi D, Lombardi M, Butters R, Kifor O et al. Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid. Nature 1993; 366: 575-580
4. Brown EM, MacLeod RJ. Extracellular Calcium Sensing and Extracellular Calcium Signaling. Physiol. Rev. 2001; 81: 239-297
5. Carnaille B, Oudar C, Pattou F, Combemale F, Rocha J, Proye C. Pancreatitis and primary hyperparathyroidism: forty cases. Aust N Z J Surg 1998; 68: 117-119
6. Cetani F, Borsari S, Vignali E, Pardi E, Picone A, Cianferotti L et al. Calcium-sensing receptor gene polymorphisms in primary hyperparathyroidism. J Endocrinol Invest 2002; 25: 614-619
7. Cetani F, Pinchera A, Pardi E, Cianferotti L, Vignali E, Picone A et al. No evidence for mutations in the calcium-sensing receptor gene in sporadic parathyroid adenomas. J Bone Miner Res 1999; 14: 878-882
8. Chou YH, Brown EM, Levi T, Crowe G, Atkinson AB, Arnqvist HJ et al. The gene responsible for familial hypocalciuric hypercalcemia maps to chromosome 3q in four unrelated families. Nat Genet 1992; 1: 295-300
9. Cole DE, Vieth R, Trang HM, Wong BY, Hendy GN, Rubin LA. Association between total serum calcium and the A986S polymorphism of the calcium-sensing receptor gene. Mol Genet Metab 2001; 72: 168-174
10. Corbetta S, Eller-Vainicher C, Filopanti M, Saeli P, Vezzoli G, Arcidiacono T et al. R990G polymorphism of the calcium-sensing receptor and renal calcium excretion in patients with primary hyperparathyroidism. Eur J Endocrinol 2006; 155: 687-692
11. Etemad B, Whitcomb D. Chronic pancreatitis: Diagnosis, classification, and new genetic developments. Gastroenterology 2001; 120: 682-707
12. Felderbauer P, Hoffmann P, Einwachter H, Bulut K, Ansorge N, Schmitz F et al. A novel mutation of the calcium sensing receptor gene is associated with chronic pancreatitis in a family with heterozygous SPINK1 mutations. BMC Gastroenterol Vol. 3: 2003; 34
13. Felderbauer P, Hoffmann P, Klein W, Bulut K, Ansorge N, Epplen JT et al. Identification of a novel calcium-sensing receptor gene mutation causing familial hypocalciuric hypercalcemia by single-strand conformation polymorphism analysis. Exp Clin Endocrinol Diabetes 2005; 113: 31-34
14. Felderbauer P, Klein W, Bulut K, Ansorge N, Dekomien G, Werner I et al. Mutations in the calcium-sensing receptor: a new genetic risk factor for chronic pancreatitis? Scand J Gastroenterol 2006; 41: 343-348
15. Koppelberg T, Bartsch D, Printz H, Hasse C, Rothmund M. [Pancreatitis in primary hyperparathyroidism (pHPT) is a complication of advanced pHPT]. Dtsch Med Wochenschr 1994; 119: 719-724
16. Kruger B, Albrecht E, Lerch MM. The Role of Intracellular Calcium Signaling in Premature Protease Activation and the Onset of Pancreatitis. Am J Pathol 2000; 157: 43-50
17. Pearce SH, Wooding C, Davies M, Tollefsen SE, Whyte MP, Thakker RV. Calcium-sensing receptor mutations in familial hypocalciuric hypercalcaemia with recurrent pancreatitis. Clin Endocrinol (Oxf) 1996; 45: 675-680
18. Racz GZ, Kittel A, Riccardi D, Case RM, Elliott AC, Varga G. Extracellular calcium sensing receptor in human pancreatic cells. Gut 2002; 51: 705-711
19. Ronni-Sivula H. The state of health of patients previously operated on for primary hyperparathyroidism compared with randomized controls. Ann Chir Gynaecol 1985; 74: 60-65
20. Sarles H, Adler G, Dani R, Frey C, Gullo L, Harada H et al. The pancreatitis classification of Marseilles-Rome 1988. Scand J Gastroenterol 1989; 24: 641-642
21. Stuckey BG, Gutteridge DH, Kent GN, Reed WD. Familial hypocalciuric hypercalcaemia and pancreatitis: no causal link proven. Aust N Z J Med 1990; 20: 718-719 , 725.
22. Sutton R, Criddle D, Raraty MC, Tepikin A, Neoptolemos JP, Petersen OH. Signal transduction, calcium and acute pancreatitis. Pancreatology 2003; 3: 497-505
23. van Lanschot JJ, Bruining HA. Primary hyperparathyroidism and pancreatitis. Neth J Surg 1984; 36: 38-41
24. Warner J, Epstein M, Sweet A, Singh D, Burgess J, Stranks S et al. Genetic testing in familial isolated hyperparathyroidism: unexpected results and their implications. J Med Genet 2004; 41: 155-160
25. Yamauchi M, Sugimoto T, Yamaguchi T, Yano S, Kanzawa M, Kobayashi A et al. Association of polymorphic alleles of the calcium-sensing receptor gene with the clinical severity of primary hyperparathyroidism. Clin Endocrinol (Oxf) 2001; 55: 373-379