Automated detection of covalent adducts to human serum albumin by immunoaffinity chromatography, on-line solution phase digestion and liquid chromatography-mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 859, Issue 2, 2007, Pages 147-156

  Hoos, Johannes S ^a   Damsten, Micaela C ^a   de Vlieger, Jon S B ^a   Commandeur, Jan N M ^a   Vermeulen, Nico P E ^a   Niessen, Wilfried M A ^a   Lingeman, Henk ^a   Irth, Hubertus ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Affinity; Albumin; Digestion; LC MS; NAPQI; On line; Pronase; Protein; Protein adduct formation

Indexed keywords

ALKYLATION; IMMUNOLOGY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; ONLINE SYSTEMS;

AFFINITY; ALBUMIN; PRONASE; PROTEIN ADDUCT FORMATION;

PROTEINS;

1 CHLORO 2,4 DINITROBENZENE; ALBUMIN ANTIBODY; ALKYLATING AGENT; CYSTEINE; GLUTAMINE; HUMAN SERUM ALBUMIN; N ACETYL 1,4 BENZOQUINONE IMINE; PARACETAMOL; PHENYLALANINE; PROLINE; PRONASE; TETRAPEPTIDE;

ALKYLATION; ARTICLE; AUTOMATION; IMMUNOAFFINITY CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; REVERSED PHASE LIQUID CHROMATOGRAPHY;

AUTOMATION; BENZOQUINONES; CHROMATOGRAPHY, AFFINITY; CHROMATOGRAPHY, LIQUID; CYSTEINE; DINITROCHLOROBENZENE; HUMANS; IMINES; MASS SPECTROMETRY; ONLINE SYSTEMS; PRONASE; SERUM ALBUMIN;

TETRA;

EID: 35748977405     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.09.015     Document Type: Article

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