Early age at onset of bipolar disorder is associated with more severe clinical features but delayed treatment seeking

Bipolar Disorders

Volumn 9, Issue 7, 2007, Pages 698-705

  Suominen, Kirsi ^a,b   Mantere, Outi ^a,b   Valtonen, Hanna ^a,b   Arvilommi, Petri ^a,b   Leppämäki, Sami ^a,b,c   Paunio, Tiina ^b,c   Isometsä, Erkki ^a,c  

^a NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^b JORVI HOSPITAL   (Finland)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

Age at onset; Bipolar I disorder; Bipolar II disorder; Diagnosis; Recognition

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; BIPOLAR I DISORDER; BIPOLAR II DISORDER; CHILD; CLINICAL FEATURE; COHORT ANALYSIS; COMORBIDITY; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DISEASE DURATION; DISEASE SEVERITY; FEMALE; FUNCTIONAL STATUS; GENDER; HELP SEEKING BEHAVIOR; HOSPITAL PATIENT; HUMAN; INTERVIEW; MAJOR CLINICAL STUDY; MALE; ONSET AGE; OUTPATIENT; PATIENT CODING; PATIENT INFORMATION; PRIORITY JOURNAL; QUESTIONNAIRE; SYMPTOM;

ADOLESCENT; ADULT; AGE FACTORS; AGE OF ONSET; BIPOLAR DISORDER; COHORT STUDIES; COMORBIDITY; DIAGNOSIS, DIFFERENTIAL; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; FEMALE; HOSPITALIZATION; HUMANS; MALE; MENTAL DISORDERS; MIDDLE AGED; OUTCOME ASSESSMENT (HEALTH CARE); PATIENT ACCEPTANCE OF HEALTH CARE; PSYCHIATRIC STATUS RATING SCALES; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX;

EID: 35748968804     PISSN: 13985647     EISSN: 13995618     Source Type: Journal    
DOI: 10.1111/j.1399-5618.2007.00388.x     Document Type: Article

References (42)

1. Carlson GA, Bromet EJ, Driessens C, Mojtabai R, Schwartz JE. Age at onset, childhood psychopathology, and 2-year outcome in psychotic bipolar disorder. Am J Psychiatry 2002; 159: 307-309.
2. Schürhoff F, Bellivier F, Jouvent R et al. Early and late onset of bipolar disorders: Two different forms of manic-depressive illness? J Affect Disord 2000; 58: 215-221.
3. Schulze TG, Müller DJ, Krauss H et al. Further evidence for age of onset being an indicator for severity in bipolar disorder. J Affect Disord 2002; 68: 343-345.
4. Carter TD, Mundo E, Parikh SV, Kennedy JL. Early age at onset as a risk factor for poor outcome of bipolar disorder. J Psychiatr Res 2003; 37: 297-303.
5. Ernst CL, Goldberg JF. Clinical features related to age at onset in bipolar disorder. J Affect Disord 2004; 82: 21-27.
6. Perlis RH, Miyahara LB, Wisniewski SR et al. Long-term implications of early onset in bipolar disorder: Data from the first 1000 participants in the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD). Biol Psychiatry 2004; 55: 875-881.
7. Geller B, Luby J. Child and adolescent bipolar disorder: A review of the past 10 years. J Am Acad Child Adolesc Psychiatry 1997; 36: 1168-1176.
8. Kowatch RA, Youngstrom EA, Danielyan A, Findling RL. Review and meta-analysis of the phenomenology and clinical characteristics of mania in children and adolescents. Bipolar Disord 2005; 7: 483-496.
9. Strober M, Schmidt-Lackner S, Freeman R, Bower S, Lampert C, DeAntonio M. Recovery and relapse in adolescents with bipolar affective illness: A 5-year naturalistic, prospective follow-up. J Am Acad Child Adolesc Psychiatry 1995; 34: 724-731.
10. Biederman J, Mick E, Bostic JQ et al. The naturalistic course of pharmacologic treatment of children with manic-like symptoms: A systematic chart review. J Clin Psychiatry 1998; 59: 628-637.
11. Geller B, Craney JL, Bolhofner K, DelBello MP, Williams M, Zimerman B. One-year recovery and relapse rates of children with a prepubertal and early adolescent bipolar disorder phenotype. Am J Psychiatry 2001; 158: 303-305.
12. Geller B, Craney JL, Bolhofner K, Nickelsburg MJ, Williams M, Zimerman B. Two-year prospective follow-up of children with a prepubertal and early adolescent bipolar disorder phenotype. Am J Psychiatry 2002; 159: 927-933.
13. Geller B, Tillman R, Craney JL, Bolhofner K. Four-year prospective outcome and natural history of mania in children with a prepubertal and early adolescent bipolar disorder phenotype. Arch Gen Psychiatry 2004; 61: 459-467.
14. Geller B, Tillman R. Prepubertal and early adolescent bipolar I disorder: Review of diagnostic validation by Robins and Guze criteria. J Clin Psychiatry 2005; 66(Suppl. 7): 21-28.
15. National Institute of Mental Health. Roundtable on prepubertal bipolar disorder. J Am Acad Child Adolesc Psychiatry 2001; 40: 871-878.
16. Rajeev J, Srinath S, Reddy YC et al. The index manic episode in juvenile onset bipolar disorder: The pattern of recovery. Can J Psychiatry 2003; 48: 52-55.
17. Jairam R, Srinath S, Girimaji SC, Seshadri SP. A prospective 4-5-year follow-up of juvenile onset bipolar disorder. Bipolar Disord 2004; 6: 386-394.
18. McGlashan TH. Adolescent versus adult onset of mania. Am J Psychiatry 1988; 145: 221-223.
19. Carlson GA, Bromet EJ, Sievers S. Phenomenology and outcome of subjects with early and adult onset psychotic mania. Am J Psychiatry 2000; 157: 213-219.
20. McElroy SL, Altshuler LA, Suppes T et al. Axis I comorbidity and its relationship to historical illness variables in 288 patients with bipolar disorder. Am J Psychiatry 2001; 158: 420-426.
21. Carlson GA, Davenport YB, Jamison K. A comparison of outcome in adolescent and later onset bipolar manic-depressive illness. Am J Psychiatry 1977; 134: 919-922.
22. Tsai SYM, Chen CC, Kuo CJ, Lee JC, Lee HC, Strakowski SM. 15-year outcome of treated bipolar disorder. J Affect Disord 2001; 63: 215-220.
23. McElroy SL, Strakowski SM, West SA, Keck PE, McConville BJ. Phenomenology of adolescent and adult mania in hospitalized patients with bipolar disorder. Am J Psychiatry 1997; 154: 44-49.
24. McMahon FJ, Stine OC, Chase GA et al. Influence of clinical subtype, sex, and lineality on age at onset of major affective disorder in a family sample. Am J Psychiatry 1994; 151: 210-215.
25. Somanath CP, Jain S, Reddy YCJ. A family study of early onset bipolar I disorder. J Affect Disord 2002; 70: 91-94.
26. Rosen LN, Rosenthal NE, Van Dusen PH, Dunner DL, Fieve RR. Age at onset and number of psychotic symptoms in bipolar I and schizoaffective disorder. Am J Psychiatry 1983; 140: 1523-1524.
27. Chengpappa KNR, Kupfer DJ, Frank E et al. Relationship of birth cohort and early age at onset of illness in a bipolar disorder case registry. Am J Psychiatry 2003; 160: 1636-1642.
28. Bellivier F, Golmard J-L, Henry C, Leboyer M, Schürhoff F. Admixture of age at onset in bipolar I affective disorder. Arch Gen Psychiatry 2001; 58: 510-512.
29. Bellivier F, Golmard J-L, Rietschel M et al. Age at onset in bipolar I affective disorder: Further evidence for three subgroups. Am J Psychiatry 2003; 160: 999-1001.
30. Kennedy N, Boydell J, Kalidindi S et al. Gender differences in incidence and age at onset of mania and bipolar disorder over a 35-year period in Camberwell, England. Am J Psychiatry 2005; 162: 257-262.
31. Mantere O, Suominen K, Leppämäki S, Valtonen H, Arvilommi P, IsometsäE. The clinical characteristics of DSM-IV bipolar I and II disorders: Baseline findings from the Jorvi Bipolar Study (JoBS). Bipolar Disord 2004; 6: 395-405.
32. Hirschfeld RMA, Williams JBW, Spitzer RL et al. Development and validation of a screening instrument for bipolar spectrum disorder: The Mood Disorder Questionnaire. Am J Psychiatry 2000: 157; 1873-1875.
33. Egeland JA, Blumenthal RL, Nee J, Sharpe L, Endicott J. Reliability and relationship of various ages of onset criteria for major affective disorder. J Affect Disord 1987; 12: 159-165.
34. Leboyer M, Henry C, Paillere-Martinot ML, Bellivier F. Age at onset in bipolar affective disorders: A review. Bipolar Disord 2005; 7: 111-118.
35. Benazzi F. Age at onset of bipolar II depressive mixed state. Psychiatry Research 2001; 103: 229-235.
36. Kessler RC, Olfson M, Berglund PA. Patterns and predictors of treatment contact after first onset of psychiatric disorders. Am J Psychiatry 1998; 155: 62-69.
37. Mojtabai R, Olfson M, Mechanic D. Perceived need and help-seeking in adults with mood, anxiety, or substance use disorders. Arch Gen Psychiatry 2002; 59: 77-84.
38. Wang PS, Berglud P, Olfson M, Pincus HA, Wells KB, Kessler RC. Failure and delay in initial treatment contact after first onset of mental disorders in the National Comorbidity Survey replication. Arch Gen Psychiatry 2005; 62: 603-613.
39. Baethge C, Smolka MN, Gruschka P et al. Does prophylaxis-delay in bipolar disorder influence outcome? Results from a long-term study of 147 patients. Acta Psychiatr Scand 2003; 107: 260-267.
40. Manji HK, Moore GJ, Rajkowska G, Chen G. Neuroplasticity and cellular resilience in mood disorders. Mol Psychiatry 2000; 5: 578-593.
41. Baldessarini RJ, Tondo L, Hennen J. Treatment-latency and previous episodes: Relationships to pretreatment morbidity and response to maintenance treatment in bipolar I and II disorders. Bipolar Disord 2003; 5: 169-179.
42. Benazzi F. Age at onset of bipolar II disorder with Axis I comorbidity. Can J Psychiatry 2000; 45: 490-491.