Sustained abdominal compression during CPR raises coronary perfusion pressures as much as vasopressor drugs

Resuscitation

Volumn 75, Issue 3, 2007, Pages 515-524

  Lottes, Aaron E ^a   Rundell, Ann E ^a   Geddes, Leslie A ^a   Kemeny, Andre E ^b   Otlewski, Michael P ^b   Babbs, Charles F ^b,c  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cardiopulmonary resuscitation (CPR); Coronary perfusion pressure (CPP); Device; Drug therapy; Epinephrine; Vasopressin; Vasopressor therapy

Indexed keywords

ADRENALIN; GLIBENCLAMIDE; VASOPRESSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CUFF; DRUG MECHANISM; HEART VENTRICLE FIBRILLATION; LIVER INJURY; NONHUMAN; PRIORITY JOURNAL; RESUSCITATION; SWINE;

ABDOMEN; ANIMALS; CARDIOPULMONARY RESUSCITATION; CORONARY CIRCULATION; DISEASE MODELS, ANIMAL; PRESSURE; SUS SCROFA; VASCULAR RESISTANCE; VASOCONSTRICTOR AGENTS; VENTRICULAR FIBRILLATION;

EID: 35748968767     PISSN: 03009572     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.resuscitation.2007.05.012     Document Type: Article

References (63)

1. Sanders A.B., Ewy G.A., and Taft T.V. Prognostic and therapeutic importance of the aortic diastolic pressure in resuscitation from cardiac arrest. Crit Care Med 12 (1984) 871-873
2. Paradis N.A., Martin G.B., Rivers E.P., et al. Coronary perfusion pressure and the return of spontaneous circulation in human cardiopulmonary resuscitation. JAMA 263 (1990) 1106-1113
3. Kern K.B. Coronary perfusion pressure during cardiopulmonary resuscitation. Baillière's Clin Anaesthesiol 14 (2000) 591-609
4. Ralston S.H., Voorhees W.D., and Babbs C.F. Intrapulmonary epinephrine during cardiopulmonary resuscitation: improved regional blood flow and resuscitation in dogs. Ann Emerg Med 13 (1984) 79-86
5. Babbs C.F., Ralston S.H., and Geddes L.A. Theoretical advantages of abdominal counterpulsation in CPR as demonstrated in a simple electrical model of the circulation. Ann Emerg Med 13 (1984) 660-671
6. Kern K.B., Ewy G.A., Voorhees W.D., Babbs C.F., and Tacker W.A. Myocardial perfusion pressure: a predictor of 24 h survival during prolonged cardiac arrest in dogs. Resuscitation 16 (1988) 241-250
7. Pearson J.W., and Redding J.S. The role of epinephrine in cardiac resuscitation. Anesth Analg 42 (1963)
8. Pearson J.W., and Redding J.S. Influence of peripheral vascular tone on cardiac resuscitation. Anesth Analg 44 (1965) 746-752
9. Redding J.S., and Pearson J.W. Evaluation of drugs for cardiac resuscitation. Anesthesiology 24 (1963) 203-207
10. Redding J.S., Haynes R.R., and Thomas J.D. Drug therapy in resuscitation from electromechanical dissociation. Crit Care Med 11 (1983)
11. Prengel A.W., Lindner K.H., Pfenninger E.G., and Georgieff M. Effects of ventilation on hemodynamics and myocardial blood flow during active compression-decompression resuscitation in pigs. Anesthesiology 84 (1996) 135-142
12. Lindner K.H., Prengel A.W., Pfenninger E.G., et al. Vasopressin improves vital organ blood flow during closed-chest cardiopulmonary resuscitation in pigs. Circulation 91 (1995) 215-221
13. Lindner K.H., Prengel A.W., Brinkmann A., Strohmenger H.U., Lindner I.M., and Lurie K.G. Vasopressin administration in refractory cardiac arrest. Ann Intern Med 124 (1996) 1061-1064
14. Babbs C.F. Preclinical studies of abdominal counterpulsation in CPR. Ann Emerg Med 13 Part 2 (1984) 761-763
15. Babbs C.F. The evolution of abdominal compression in cardiopulmonary resuscitation. Acad Emerg Med 1 (1994) 469-477
16. Chandra N., Snyder L.D., and Weisfeldt M.L. Abdominal binding during cardiopulmonary resuscitation in man. JAMA 246 (1981) 351-353
17. Coletti R.H., Kaskel P.S., Cohen S.R., and Bregman D. Abdominal counterpulsation (AC)-a new concept in circulatory assistance. Trans Am Soc Artif Intern Organs 28 (1982) 563-566
18. Redding J.S. Abdominal compression in cardiopulmonary resuscitation. Anesth Analg 50 (1971) 668-675
19. Sack J.B., Kesselbrenner M.B., and Bregman D. Survival from in-hospital cardiac arrest with interposed abdominal counterpulsation during cardiopulmonary resuscitation. JAMA 267 (1992) 379-385
20. Woodhouse S.P., Cox S., Boyd P., Case C., and Weber M. High dose and standard dose adrenaline do not alter survival, compared with placebo, in cardiac arrest. Resuscitation 30 (1995) 243-249
21. Marwick T.H., Case C., Siskind V., and Woodhouse S.P. Adverse effect of early high-dose adrenaline on outcome of ventricular fibrillation. Lancet 2 (1988) 66-68
22. Herlitz J., Ekstrom L., Wennerblom B., Axelsson A., Bang A., and Holmberg S. Adrenaline in out-of-hospital ventricular fibrillation. Does it make any difference?. Resuscitation 29 (1995) 195-201
23. Ditchey R.V., Rubio-Perez A., and Slinker B.K. Beta-adrenergic blockade reduces myocardial injury during experimental cardiopulmonary resuscitation. J Am Coll Cardiol 24 (1994) 804-812
24. Tang W., Weil M.H., Sun S., Noc M., Yang L., and Gazmuri R.J. Epinephrine increases the severity of postresuscitation myocardial dysfunction. Circulation 92 (1995) 3089-3093
25. Huang L., Sun S., Fang X., Tang W., and Weil M.H. Simultaneous blockade of alpha1- and beta-actions of epinephrine during cardiopulmonary resuscitation. Crit Care Med 34 (2006) S483-S485
26. Huang L., Weil M.H., Cammarata G., Sun S., and Tang W. Nonselective beta-blocking agent improves the outcome of cardiopulmonary resuscitation in a rat model. Crit Care Med 32 (2004) S378-S380
27. Chang W.T., Ma M.H., Chien K.L., et al. Postresuscitation myocardial dysfunction: correlated factors and prognostic implications. Intens Care Med 33 (2007) 88-95
28. Olson D.W., Thakur R., Stueven H.A., et al. Randomized study of epinephrine versus methoxamine in prehospital ventricular fibrillation. Ann Emerg Med 18 (1989) 250-253
29. Harris Jr. L.C., Kirimli B., and Safar P. Augmentation of artificial circulation during cardiopulmonary resuscitation. Anesthesiology 28 (1967) 730-734
30. McDowell M.A., Fryar C.D., Hirsch R., and Ogden C.L. Anthropometric reference data for children and adults: U.S. population, 1999-2002. Adv Data (2005) 1-5
31. Hardman JG, Limbard LE, Molinoff PB, Ruddon RW, Gillman AG. Goodman and Gilman's the pharmacological basis of therapeutics. New York: McGraw-Hill; 1996.
32. Vanelli G., Hussain S.N., and Aguggini G. Glibenclamide, a blocker of ATP-sensitive potassium channels, reverses endotoxin-induced hypotension in pig. Exp Physiol 80 (1995) 167-170
33. Aguggini G., Dimori M., Vanelli G., and Albertini M. The effects of glibenclamide, a blocker of K+ ATP-sensitive potassium channels, on diaphragmatic fatigue during endotoxaemia in pigs. Vet Res Commun 20 (1996) 183-190
34. Maybauer D.M., Salsbury J.R., Westphal M., et al. The ATP-sensitive potassium-channel inhibitor glibenclamide improves outcome in an ovine model of hemorrhagic shock. Shock 22 (2004) 387-391
35. Redding J.S., and Pearson J.W. Resuscitation from asphyxia. JAMA 182 (1962) 283-286
36. Pearson J.W., and Redding J.S. Peripheral vascular tone on cardiac resuscitation. Anesth Analg 44 (1965) 746-752
37. Redding J.S., and Pearson J.W. Resuscitation from ventricular fibrillation. Drug therapy. JAMA 203 (1968) 255-260
38. Yakaitis R.W., Otto C.W., and Blitt C.D. Relative importance of alpha and beta adrenergic receptors during resuscitation. Crit Care Med 7 (1979) 293-296
39. Stiell I.G., Hebert P.C., Weitzman B.N., et al. High-dose epinephrine in adult cardiac arrest. N Engl J Med 327 (1992) 1045-1050
40. Brown C.G., Martin D.R., Pepe P.E., et al. A comparison of standard-dose and high-dose epinephrine in cardiac arrest outside the hospital. The Multicenter High-Dose Epinephrine Study Group. N Engl J Med 327 (1992) 1051-1055
41. Callaham M., Madsen C.D., Barton C.W., Saunders C.E., and Pointer J. A randomized clinical trial of high-dose epinephrine and norepinephrine vs. standard-dose epinephrine in prehospital cardiac arrest. JAMA 268 (1992) 2667-2672
42. Choux C., Gueugniaud P.Y., Barbieux A., et al. Standard doses versus repeated high doses of epinephrine in cardiac arrest outside the hospital. Resuscitation 29 (1995) 3-9
43. Gueugniaud P.Y., Mols P., Goldstein P., et al. A comparison of repeated high doses and repeated standard doses of epinephrine for cardiac arrest outside the hospital. European Epinephrine Study Group. N Engl J Med 339 (1998) 1595-1601
44. Rivers E.P., Wortsman J., Rady M.Y., Blake H.C., McGeorge F.T., and Buderer N.M. The effect of the total cumulative epinephrine dose administered during human CPR on hemodynamic, oxygen transport, and utilization variables in the postresuscitation period. Chest 106 (1994) 1499-1507
45. Behringer W., Kittler H., Sterz F., et al. Cumulative epinephrine dose during cardiopulmonary resuscitation and neurologic outcome. Ann Intern Med 129 (1998) 450-456
46. Lindner K.H., Brinkmann A., Pfenninger E.G., Lurie K.G., Goertz A., and Lindner I.M. Effect of vasopressin on hemodynamic variables, organ blood flow, and acid-base status in a pig model of cardiopulmonary resuscitation. Anesth Analg 77 (1993) 427-435
47. Prengel A.W., Lindner K.H., Keller A., and Lurie K.G. Cardiovascular function during the postresuscitation phase after cardiac arrest in pigs: a comparison of epinephrine versus vasopressin. Crit Care Med 24 (1996) 2014-2019
48. Wenzel V., Linder K.H., Augenstein S., Prengel A.W., and Strohmenger H.U. Vasopressin combined with epinephrine decreases cerebral perfusion compared with vasopressin alone during cardiopulmonary resuscitation in pigs. Stroke 29 (1998) p. 1462-7; discussion, p. 1467-8
49. Wenzel V., Lindner K.H., Prengel A.W., et al. Vasopressin improves vital organ blood flow after prolonged cardiac arrest with postcountershock pulseless electrical activity in pigs. Crit Care Med 27 (1999) 486-492
50. Wenzel V., Lindner K.H., Krismer A.C., Miller E.A., Voelckel W.G., and Lingnau W. Repeated administration of vasopressin but not epinephrine maintains coronary perfusion pressure after early and late administration during prolonged cardiopulmonary resuscitation in pigs. Circulation 99 (1999) 1379-1384
51. Babar S.I., Berg R.A., Hilwig R.W., Kern K.B., and Ewy G.A. Vasopressin versus epinephrine during cardiopulmonary resuscitation: a randomized swine outcome study. Resuscitation 41 (1999) 185-192
52. Wenzel V., Krismer A.C., Arntz H.R., Sitter H., Stadlbauer K.H., and Lindner K.H. A comparison of vasopressin and epinephrine for out-of-hospital cardiopulmonary resuscitation. N Engl J Med 350 (2004) 105-113
53. Ditchey R.V. High-dose epinephrine does not improve the balance between myocardial oxygen supply and demand during cardiopulmonary resuscitation in dogs. JACC 3 (1984)
54. Krismer A.C., Paradis N.A., Wenzel V., and Southall J. Use of vasopressor drugs in cardiac arrest. In: Ornato J.P., and Peberdy M.A. (Eds). Cardiopulmonary resuscitation (2005), Humana Press, Totowa, NJ
55. Wik L., Naess P.A., Ilebekk A., and Steen P.A. Simultaneous active compression-decompression and abdominal binding increase carotid blood flow additively during cardiopulmonary resuscitation (CPR) in pigs. Resuscitation 28 (1994) 55-64
56. Niemann J.T., Rosborough J.P., Ung S., and Criley J.M. Hemodynamic effects of continuous abdominal binding during cardiac arrest and resuscitation. Am J Cardiol 53 (1984) 269-274
57. Rudikoff M.T., Maughan W.L., Effron M., Freund P., and Weisfeldt M.L. Mechanisms of blood flow during cardiopulmonary resuscitation. Circulation 61 (1980) 345-352
58. Niemann J.T., Rosborough J.P., and Criley J.M. Continuous external counterpressure during closed-chest resuscitation: a critical appraisal of the military antishock trouser garment and abdominal binder. Circulation 74 (1986) IV102-IV107
59. Niemann J.T., Rosborough J.P., Ung S., and Criley J.M. Coronary perfusion pressure during experimental cardiopulmonary resuscitation. Ann Emerg Med 11 (1982) 127-131
60. Lottes A.E. Investigation of an abdominal compression device for improving CPR (2006), School of Biomedical Engineering, Purdue University, West Lafayette, IN
61. Babbs C.F., and Kern K.B. Optimum compression to ventilation ratios in CPR under realistic, practical conditions: a physiological and mathematical analysis. Resuscitation 54 (2002) 147-157
62. Kern K.B., Hilwig R.W., Berg R.A., and Ewy G.A. Efficacy of chest compression-only BLS CPR in the presence of an occluded airway. Resuscitation 39 (1998) 179-188
63. Berg R.A., Kern K.B., Hilwig R.W., et al. Assisted ventilation does not improve outcome in a porcine model of single-rescuer bystander cardiopulmonary resuscitation. Circulation 95 (1997) 1635-1641