Molecular Basis of the Antimutagenic Activity of the House-Cleaning Inosine Triphosphate Pyrophosphatase RdgB from Escherichia coli

Journal of Molecular Biology

Volumn 374, Issue 4, 2007, Pages 1091-1103

  Savchenko, Alexei ^a   Proudfoot, Michael ^a   Skarina, Tatiana ^a   Singer, Alexander ^a   Litvinova, Olga ^a   Sanishvili, Ruslan ^b   Brown, Greg ^a   Chirgadze, Nickolay ^c   Yakunin, Alexander F ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b ARGONNE NATIONAL LABORATORY   (United States)

^c UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

crystal structure; house cleaning enzyme; inosine triphosphate pyrophosphatase; noncanonical nucleotides; site directed mutagenesis

Indexed keywords

CALCIUM ION; DNA; HYPOXANTHINE; INORGANIC PYROPHOSPHATASE; INOSINE PHOSPHATE; INOSINE TRIPHOSPHATE; INOSINE TRISPHOSPHATE PYROPHOSPHATASE RDGB; NUCLEIC ACID; RNA; UNCLASSIFIED DRUG; XANTHINE; XANTHOSINE TRIPHOSPHATE;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

ESCHERICHIA COLI;

EID: 35748964414     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2007.10.012     Document Type: Article

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