메뉴 건너뛰기




Volumn 51, Issue 3, 2007, Pages 213-218

Localization of MTT formazan in lipid droplets. An alternative hypothesis about the nature of formazan granules and aggregates

Author keywords

Amyloid; Cholesterol; Formazan; Lipid droplets; MTT; NBD cholesterol; Nile Red; Peptides

Indexed keywords

3 (4 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; AMYLOID; BROMINE DERIVATIVE; FAT DROPLET; FORMAZAN; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (12 28); AMYLOID BETA PROTEIN (25 35); AMYLOID BETA-PROTEIN (12-28); AMYLOID BETA-PROTEIN (25-35); ASCORBIC ACID; CHOLESTEROL; COLORING AGENT; FIXATIVE; FORMALDEHYDE; LIPID; MTT FORMAZAN; NILE RED; OXAZINE DERIVATIVE; PEPTIDE FRAGMENT; TETRAZOLIUM;

EID: 35748959360     PISSN: 1121760X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (22)

References (17)
  • 1
    • 0031668862 scopus 로고    scopus 로고
    • Amyloid beta protein inhibits cellular MTT reduction not by suppression of mitochondrial succinate dehydrogenase but by acceleration of MTT formazan exocytosis in cultured rat cortical astrocytes
    • Abe K, Saito H. Amyloid beta protein inhibits cellular MTT reduction not by suppression of mitochondrial succinate dehydrogenase but by acceleration of MTT formazan exocytosis in cultured rat cortical astrocytes. Neurosci Res 1998;31:295-305.
    • (1998) Neurosci Res , vol.31 , pp. 295-305
    • Abe, K.1    Saito, H.2
  • 2
    • 0032759230 scopus 로고    scopus 로고
    • Cholesterol does not affect the toxicity of amyloid beta fragment but mimics its effect on MTT formazan exocytosis in cultured rat hippocampal neurons
    • Abe K, Saito H. Cholesterol does not affect the toxicity of amyloid beta fragment but mimics its effect on MTT formazan exocytosis in cultured rat hippocampal neurons. Neurosci Res 1999;35:165-74.
    • (1999) Neurosci Res , vol.35 , pp. 165-174
    • Abe, K.1    Saito, H.2
  • 3
    • 0017114371 scopus 로고
    • Tetrazolium salts: A consumer's guide
    • Altman FP. Tetrazolium salts: a consumer's guide. Histochem J 1976;8:471-85.
    • (1976) Histochem J , vol.8 , pp. 471-485
    • Altman, F.P.1
  • 4
    • 0034951668 scopus 로고    scopus 로고
    • Intra-and intercellular distribution of mitochondrial probes and changes after treatment with MDR modulators
    • Diaz G, Diana A, Falchi AM, Gremo F, Pani A, Batetta B, et al. Intra-and intercellular distribution of mitochondrial probes and changes after treatment with MDR modulators. IUBMB Life 2001;51:121-6.
    • (2001) IUBMB Life , vol.51 , pp. 121-126
    • Diaz, G.1    Diana, A.2    Falchi, A.M.3    Gremo, F.4    Pani, A.5    Batetta, B.6
  • 5
    • 0034724682 scopus 로고    scopus 로고
    • High density lipoprotein-mediated cholesterol uptake and targeting to lipid droplets in intact L-cell fibroblasts. A single- and multiphoton fluorescence approach
    • Frolov A, Petrescu A, Atshaves BP, So PT, Gratton E, Serrero G, et al. High density lipoprotein-mediated cholesterol uptake and targeting to lipid droplets in intact L-cell fibroblasts. A single- and multiphoton fluorescence approach. J Biol Chem 2000;275:12769-80.
    • (2000) J Biol Chem , vol.275 , pp. 12769-12780
    • Frolov, A.1    Petrescu, A.2    Atshaves, B.P.3    So, P.T.4    Gratton, E.5    Serrero, G.6
  • 6
    • 0033532236 scopus 로고    scopus 로고
    • Enhancement of MTT, a tetrazolium salt, exocytosis by amyloid beta-protein and chloroquine in cultured rat astrocytes
    • Isobe I, Michikawa M, Yanagisawa K. Enhancement of MTT, a tetrazolium salt, exocytosis by amyloid beta-protein and chloroquine in cultured rat astrocytes. Neurosci Lett 1999;266:129-32.
    • (1999) Neurosci Lett , vol.266 , pp. 129-132
    • Isobe, I.1    Michikawa, M.2    Yanagisawa, K.3
  • 7
    • 0000223689 scopus 로고
    • Spectral absorption and fluorescence of dyes in the molecular state
    • Jelley E. Spectral absorption and fluorescence of dyes in the molecular state. Nature 1936;138:1009-10.
    • (1936) Nature , vol.138 , pp. 1009-1010
    • Jelley, E.1
  • 8
    • 7244225197 scopus 로고    scopus 로고
    • Detecting bioactive amyloid beta peptide species in Alzheimer's disease
    • Liu Y, Dargusch R, Banh C, Miller CA, Schubert D. Detecting bioactive amyloid beta peptide species in Alzheimer's disease. J Neurochem 2004;91:648-56.
    • (2004) J Neurochem , vol.91 , pp. 648-656
    • Liu, Y.1    Dargusch, R.2    Banh, C.3    Miller, C.A.4    Schubert, D.5
  • 9
    • 0030852948 scopus 로고    scopus 로고
    • Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction
    • Liu Y, Peterson DA, Kimura H, Schubert D. Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction. J Neurochem 1997;69:581-93.
    • (1997) J Neurochem , vol.69 , pp. 581-593
    • Liu, Y.1    Peterson, D.A.2    Kimura, H.3    Schubert, D.4
  • 10
    • 0032573097 scopus 로고    scopus 로고
    • Amyloid beta peptide alters intracellular vesicle trafficking and cholesterol homeostasis
    • Liu Y, Peterson DA, Schubert D. Amyloid beta peptide alters intracellular vesicle trafficking and cholesterol homeostasis. Proc Natl Acad Sci USA 1998;95:13266-71.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13266-13271
    • Liu, Y.1    Peterson, D.A.2    Schubert, D.3
  • 11
    • 0030695856 scopus 로고    scopus 로고
    • Cytotoxic amyloid peptides inhibit cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction by enhancing MTT formazan exocytosis
    • Liu Y, Schubert D. Cytotoxic amyloid peptides inhibit cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction by enhancing MTT formazan exocytosis. J Neurochem 1997;69:2285-93.
    • (1997) J Neurochem , vol.69 , pp. 2285-2293
    • Liu, Y.1    Schubert, D.2
  • 12
    • 0035865244 scopus 로고    scopus 로고
    • A cell-based method for the detection of nanomolar concentrations of bioactive amyloid
    • Liu Y, Piasecki D. A cell-based method for the detection of nanomolar concentrations of bioactive amyloid. Anal Biochem 2001;289:130-6.
    • (2001) Anal Biochem , vol.289 , pp. 130-136
    • Liu, Y.1    Piasecki, D.2
  • 13
    • 33646168160 scopus 로고    scopus 로고
    • Martin S, Parton R. G. Lipid droplets: a unified view of a dynamic organelle. Nat Rev Mol Cell Biol 2006;7:373-8.
    • Martin S, Parton R. G. Lipid droplets: a unified view of a dynamic organelle. Nat Rev Mol Cell Biol 2006;7:373-8.
  • 14
    • 11144317785 scopus 로고    scopus 로고
    • Kinetics of MTT-formazan exocytosis in phagocytic and non-phagocytic cells
    • Molinari BL, Tasat DR, Palmieri MA, Cabrini RL. Kinetics of MTT-formazan exocytosis in phagocytic and non-phagocytic cells. Micron 2005;36:177-83.
    • (2005) Micron , vol.36 , pp. 177-183
    • Molinari, B.L.1    Tasat, D.R.2    Palmieri, M.A.3    Cabrini, R.L.4
  • 15
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983;65:55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 16
    • 0026514791 scopus 로고
    • The MTT assay for chemosensitivity testing of human tumors of the central nervous system. Part I: Evaluation of test-specific variables
    • Nikkhah G, Tonn JC, Hoffmann O, Kraemer HP, Darling JL, Schonmayr R, Schachenmayr W. The MTT assay for chemosensitivity testing of human tumors of the central nervous system. Part I: Evaluation of test-specific variables. J Neurooncol 1992;13:1-11.
    • (1992) J Neurooncol , vol.13 , pp. 1-11
    • Nikkhah, G.1    Tonn, J.C.2    Hoffmann, O.3    Kraemer, H.P.4    Darling, J.L.5    Schonmayr, R.6    Schachenmayr, W.7
  • 17
    • 0029040824 scopus 로고
    • The intracellular component of cellular 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) reduction is specifically inhibited by beta-amyloid peptides
    • Shearman MS, Hawtin SR, Tailor VJ. The intracellular component of cellular 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) reduction is specifically inhibited by beta-amyloid peptides. J Neurochem 1995;65:218-27.
    • (1995) J Neurochem , vol.65 , pp. 218-227
    • Shearman, M.S.1    Hawtin, S.R.2    Tailor, V.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.