Lipase-catalyzed esterification of conjugated linoleic acid with L-carnitine in solvent-free system and acetonitrile

Bioprocess and Biosystems Engineering

Volumn 30, Issue 5, 2007, Pages 331-336

  Li, Zhen ^a   Yang, Depo ^a   Jiang, Lin ^a   Ji, Junfeng ^b   Ji, Hongbin ^b   Zeng, Xiaohui ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b Zhongshan Unicare Natural Medicine Co Ltd   (China)

Author keywords

Conjugated linoleic acid; Esterification; L Carnitine; Lipase

Indexed keywords

ACETONITRILE; BIOCATALYSTS; ESTERIFICATION; ESTERS; MOLECULAR SIEVES;

CARNITINE; CONJUGATED LINOLEIC ACID; LINOLEIC ACIDS; SOLVENT FREE SYSTEMS;

LIPASES;

ACETONITRILE; CARNITINE; CONJUGATED LINOLEIC ACID; TRIACYLGLYCEROL LIPASE; WATER; ACETONITRILE DERIVATIVE; ESTER; FATTY ACID; LINOLEIC ACID; SOLVENT;

ARTICLE; BIOCATALYST; CANDIDA ANTARCTICA; CANDIDA RUGOSA; CATALYSIS; CHEMICAL REACTION; ELECTROSPRAY MASS SPECTROMETRY; ENZYME ANALYSIS; ESTERIFICATION; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; BIOTECHNOLOGY; CHEMICAL MODEL; CHEMISTRY; GAS CHROMATOGRAPHY; MASS SPECTROMETRY; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ACETONITRILES; BIOTECHNOLOGY; CARNITINE; CATALYSIS; CHROMATOGRAPHY, GAS; ESTERS; FATTY ACIDS; LINOLEIC ACID; LIPASE; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MODELS, CHEMICAL; SOLVENTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; WATER;

EID: 35748952863     PISSN: 16157591     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00449-007-0129-9     Document Type: Article

References (24)

1. Sehat N, Kramer JK, Mossoba MM, Yurawecz MP, Roach JA, Eulitz K et al (1998) Identification of conjugated linoleic acid isomers in cheese by gas chromatography silver ion high performance liquid chromatography and mass spectral reconstructed ion profiles Lipids 33:963-971
2. Clement I, Petal (1994) Conjugated linoleic acid suppresses mammary carcinogenesis and proliferative activity of the mammary gland in the rat. Cancer Res 54:1212-1215
3. Van den Berg JJ, Cook NE, Tribble DL (1995) Reinvestigation of the antioxidant properties of conjugated linoleic acid. Lipids 30:599-605
4. Hayek MG, Han SN (1999) Dietary conjugated linoleic acid influences the immune response of young and old Mice. J Nutr 129:32-38
5. Park Y, Albright KJ, Storkson JM, Liu W, Cook ME, Pariza MW (1999) Changes in body composition in mice during feeding and withdraw of conjugated linoleic acid. Lipids 34:243-248
6. Rebouche CJ, Seim H (1998) Carnitine metabolism and its regulation in microorganisms and mammals. Annu Rev Nutr 18:39-61
7. Martin JC, Gregoire S, Siess MH, Genty M, Chardigny JM, Berdeaux O et al (2000) Effects of conjugated linoleic acid isomers on lipid-metabolizing enzymes in male rats. Lipids 35:91-98
8. Retter AS (1999) Carnitine and its role in cardiovascular disease. Heart Dis 1:108-113
9. Lee KN, Kritchevsky D, Pariza MW (1994) Conjugated linoleic acid and atherosclerosis in rabbits. Atherosclerosis 108:19-25
10. Gao C, Whitcombe MJ, Vulfson EN (1999) Enzymatic synthesis of dimeric and trimeric sugar-fatty acid esters. Enzyme Microb Technol 25:264-270
11. Hossen M, Hernandez E (2005) Enzyme-catalyzed synthesis of structured phospholipids with conjugated linoleic acid. Eur J Lipid Sci Technol 107:730-736
12. Babali B, Aksoyh A,Tuter M, Ustun G (2001) Enzymatic esterification of (-)-menthol with fatty acids in solvent by a commercial lipase from Candida rugosa. J Am Oil Chem Soc 78:53-56
13. Song QX, Zhao Y, Xu WQ, Zhou WY, Wei DZ (2006) Enzymatic synthesis of l-ascorbyl linoleate in organic media. Bioprocess Biosyst Eng 28:211-215
14. Tesser R, Di Serio M, Guida M, Nastasi M, Santacesaria E (2005) Kinetics of oleic acid esterification with methanol in the presence of triglycerides. Ind Eng Chem Res 44:7978-7982
15. Cervenka J, Osmundsen H (1982) Synthesis of unsaturated carnitine esters with N-acyl imidazoles. J Lipid Res 23:1243-1246
16. Lozano P, Daz M, de Diego T, Iborra JL (2003) Ester synthesis from trimethylammonium alcohols in dry organic media catalyzed by immobilized Candida antarctica lipase B. Biotechnol Bioeng 82:352-358
17. Vu PL, Shin JA, Lim CH, Lee KT (2004) Lipase-catalyzed production of phytosteryl esters and their crystallization behavior in corn oil. Food Res Int 37:175-180
18. Ward OP, Fang J, Li Z (1997) Lipase-catalyzed synthesis of a sugar ester containing arachidonic acid. Enzyme Microb Technol 20:52-56
19. Yadav GD, Lathi PS (2004) Synthesis of citronellol laurate in organic media catalyzed by immobilized lipases: kinetic studies. J Mol Cat B Enzym 27:113-119
20. Foresti ML, Errazu A, Ferreira ML (2005) Effect of several reaction parameters in the solvent-free ethyl oleate synthesis using Candida rugosa lipase immobilised on polypropylene. Biochem Eng J 25:65-77
21. Ferńandez-Lafuente R, Armiśen P, Sabuquillo P, Ferńandez-Lorente G, Guiśan JM (1998) Immobilisation of lipases by selective adsorption on hydrophobic supports. Chem Phys Lipids 93:185-197
22. Laudani CG, Habulin M, Primožič M, Knez Ž, Della Porta G, Reverchon E (2006) Optimisation of n-octyl oleate enzymatic synthesis over Rhizomucor miehei lipase. Bioprocess Biosyst Eng 29:119-127
23. Wehtje E, Adlercreutz P (1997) Water activity and substrate concentration effects on lipase activity. Biotechnol Bioeng 55:798-806
24. Maha KC, Sylviane P, Daniel T, Didier T, Werner K (2002) Role of water activity on the synthesis of geranyl butyrate by a Mucor miehei esterase in a solvent-free system. Biotechnol Lett 24:1951-1955