Concurrent gain of 17q and the MYC oncogene in a medullomyoblastoma

Neuropathology

Volumn 27, Issue 6, 2007, Pages 556-560

  Lindberg, Eva ^a   Persson, Annette ^a   Øra, Ingrid ^a   Mertens, Fredrik ^a   Englund, Elisabet ^a   Gisselsson, David ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Cerebellar tumors; Cytogenetics; Isochromosome; Medullomyoblastoma; MYC; Pediatric tumors; TP53

Indexed keywords

CARBOPLATIN; CYCLOPHOSPHAMIDE; ETOPOSIDE; METHOTREXATE; VINCRISTINE;

ARTICLE; CANCER SURGERY; CASE REPORT; CHROMOSOME 17Q; CHROMOSOME 8; CHROMOSOME ANALYSIS; CHROMOSOME BANDING PATTERN; CLONING; DIPLOIDY; GENE TRANSLOCATION; GENETIC ANALYSIS; GRANULAR CELL TUMOR; HUMAN; HUMAN TISSUE; ISOCHROMOSOME; KARYOTYPING; MALE; MEDULLOMYOBLASTOMA; MONOSOMY; MONOSOMY 9; MYOBLAST; NEUROECTODERM; NEUROPATHOLOGY; ONCOGENE MYC; PATHOGENESIS; PRESCHOOL CHILD; PRIORITY JOURNAL; TRISOMY; TRISOMY 13; TRISOMY 5;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CEREBELLAR NEOPLASMS; CHILD, PRESCHOOL; CHROMOSOME ABERRATIONS; CHROMOSOME BANDING; CHROMOSOMES, HUMAN, PAIR 17; GENES, MYC; HUMANS; IMMUNOHISTOCHEMISTRY; MAGNETIC RESONANCE IMAGING; MALE; MEDULLOBLASTOMA; NEUROSURGICAL PROCEDURES; SPECTRAL KARYOTYPING;

EID: 35748937317     PISSN: 09196544     EISSN: 14401789     Source Type: Journal    
DOI: 10.1111/j.1440-1789.2007.00810.x     Document Type: Article

References (23)

1. Marinesco G, Goldstein M. On an anatomical form of medulloblastoma not yet described, medullomyoblastoma. Ann Anat Pathol (Paris) 1933 10 : 513 525.
2. Helton KJ, Fouladi M, Boop FA et al. Medullomyoblastoma: a radiographic and clinicopathologic analysis of six cases and review of the literature. Cancer 2004 101 : 1445 1454.
3. Lata M, Mahapatra AK, Sarkar C, Roy S. Medullomyoblastoma. A case report. Indian J Cancer 1989 26 : 240 246.
4. Mahapatra AK, Sinha AK, Sharma MC. Medullomyoblastoma. A rare cerebellar tumour in children. Childs Nerv Syst 1998 14 : 312 316.
5. Pazanin L, Jadro-Santel D, Poljakovic Z, Zarkovic K, Hlavka V. Medullomyoblastoma. Neurologija 1990 39 : 199 208.
6. Jaiswal AK, Jaiswal S, Mahapatra AK, Sharma MC. Unusually long survival in a case of medullomyoblastoma. J Clin Neurosci 2005 12 : 961 963.
7. Giordana M, Wiestler OD. Medullomyoblastoma. In : Kleihues P, Cavanee K, eds. World Health Organization Classification of Tumours, Pathology and Genetics of Tumours of the Nervous System. Lyon : IARC Press, 2000 138 139.
8. Leonard JR, Cai DX, Rivet DJ et al. Large cell/anaplastic medulloblastomas and medullomyoblastomas: clinicopathological and genetic features. J Neurosurg 2001 95 : 82 88.
9. Nagashima K, Yasui K, Kimura J, Washizu M, Yamaguchi K, Mori W. Induction of brain tumors by a newly isolated JC virus (Tokyo-1 strain). Am J Pathol 1984 116 : 455 463.
10. Kuwamura M, Shirota A, Takada A, Yamate J, Kotani T, Sakuma S. Spontaneous and ethyl-nitrosourea-induced medullomyoblastomas in cerebellar vermis defect (CVD) mutant rats. Acta Neuropathol (Berl) 2000 99 : 285 288.
11. Marino S. Medulloblastoma: developmental mechanisms out of control. Trends Mol Med 2005 11 : 17 22.
12. Ingraham F, Bailey O. Cystic teratomas and teratoid tumors of the central nervous system in infancy and childhood. J Neurosurg 1946 3 : 511 532.
13. Walter GF, Brucher JM. Ultrastructural study of medullomyoblastoma. Acta Neuropathol (Berl) 1979 48 : 211 214.
14. Stahlberger R, Friede RL. Fine structure of myomedulloblastoma. Acta Neuropathol (Berl) 1977 37 : 43 48.
15. Smith TW, Davidson RI. Medullomyoblastoma. A histologic, immunohistochemical, and ultrastructural study. Cancer 1984 54 : 323 332.
16. Gisselsson D, Höglund M, Mertens F, Mitelman F, Mandahl N. Chromosomal organization of amplified chromosome 12 sequences in mesenchymal tumors detected by fluorescence in situ hybridization. Genes Chromosomes Cancer 1998 23 : 203 212.
17. Tanke HJ, Wiegant J, van Gijlswijk RP et al. New strategy for multi-colour fluorescence in situ hybridisation: COBRA: COmbined Binary RAtio labelling. Eur J Hum Genet 1999 7 : 2 11.
18. Gisselsson D, Hibbard MK, Dal Cin P et al. PLAG1 alterations in lipoblastoma: involvement in varied mesenchymal cell types and evidence for alternative oncogenic mechanisms. Am J Pathol 2001 159 : 955 962.
19. Bergmann M, Pietsch T, Herms J, Janus J, Spaar HJ, Terwey B. Medullomyoblastoma: a histological, immunohistochemical, ultrastructural and molecular genetic study. Acta Neuropathol (Berl) 1998 95 : 205 212.
20. Mitelman F, Johansson B, Mertens F, eds. Mitelman Database of Chromosome Aberration in Cancer. 2006. [Accessed 24 September 2007.] Available from URL: http://cgap.nci.nih.gov/Chromosomes/Mitelman
21. Stearns D, Chaudhry A, Abel TW, Burger PC, Dang CV, Eberhart CG. c-myc overexpression causes anaplasia in medulloblastoma. Cancer Res 2006 66 : 673 681.
22. Shakhova O, Leung C, van Montfort E, Berns A, Marino S. Lack of Rb and p53 delays cerebellar development and predisposes to large cell anaplastic medulloblastoma through amplification of N-Myc and Ptch2. Cancer Res 2006 66 : 5190 5200.
23. Mendrzyk F, Radlwimmer B, Joos S et al. Genomic and protein expression profiling identifies CDK6 as novel independent prognostic marker in medulloblastoma. J Clin Oncol 2005 23 : 8853 8862.