Role of the structural domains in the functional properties of pancreatic lipase-related protein 2

FEBS Journal

Volumn 274, Issue 22, 2007, Pages 6011-6023

  Berton, Amélie ^a   Sebban Kreuzer, Corinne ^a   Crenon, Isabelle ^a  

^a INSERM   (France)

Author keywords

Chimera; Colipase; Domain; Pancreatic lipase; PLRP2

Indexed keywords

BILE SALT; CHIMERIC PROTEIN; COLIPASE; PANCREATIC LIPASE RELATED PROTEIN 2; SODIUM CHLORIDE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CHROMATOGRAPHY; DENATURATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME SPECIFICITY; ENZYME STABILITY; INSECT CELL; LIPOLYSIS; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; BASE SEQUENCE; DNA, VIRAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; LIPASE; LIPOLYSIS; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EQUIDAE; HEXAPODA;

EID: 35748933165     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2007.06123.x     Document Type: Article

References (47)

1. Giller T, Buchwald P, Blum-Kaelin D Hunziker W (1992) Two novel human pancreatic lipase related proteins, hPLRP1 and hPLRP2. Differences in colipase dependence and in lipase activity. J Biol Chem 267, 16509 16516.
2. Kerfelec B, LaForge KS, Puigserver A Scheele G (1986) Primary structures of canine pancreatic lipase and phospholipase A2 messenger RNAs. Pancreas 1, 430 437.
3. Hjorth A, Carriere F, Cudrey C, Woldike H, Boel E, Lawson DM, Ferrato F, Cambillau C, Dodson GG, Thim L et al. (1993) A structural domain (the lid) found in pancreatic lipases is absent in the guinea pig (phospho) lipase. Biochemistry 32, 4702 4707.
4. Payne RM, Sims HF, Jennens ML Lowe ME (1994) Rat pancreatic lipase and two related proteins: enzymatic properties and mRNA expression during development. Am J Physiol 266, G914 G921.
5. Wicker-Planquart C Puigserver A (1992) Primary structure of rat pancreatic lipase mRNA. FEBS Lett 296, 61 66.
6. Remington SG, Lima PH Nelson JD (1999) Pancreatic lipase-related protein 1 mRNA in female mouse lacrimal gland. Invest Ophthalmol Vis Sci 40, 1081 1090.
7. Wishart MJ, Andrews PC, Nichols R, Blevins GT Jr., Logsdon CD Williams JA (1993) Identification and cloning of GP-3 from rat pancreatic acinar zymogen granules as a glycosylated membrane-associated lipase. J Biol Chem 268, 10303 10311.
8. Jayne S, Kerfelec B, Foglizzo E, Chapus C Crenon I (2002) High expression in adult horse of PLRP2 displaying a low phospholipase activity. Biochim Biophys Acta 1594, 255 265.
9. Thirstrup K, Verger R Carriere F (1994) Evidence for a pancreatic lipase subfamily with new kinetic properties. Biochemistry 33, 2748 2756.
10. Grusby MJ, Nabavi N, Wong H, Dick RF, Bluestone JA, Schotz MC Glimcher LH (1990) Cloning of an interleukin-4 inducible gene from cytotoxic T lymphocytes and its identification as a lipase. Cell 60, 451 459.
11. Sias B, Ferrato F, Pellicer-Rubio MT, Forgerit Y, Guillouet P, Leboeuf B Carriere F (2005) Cloning and seasonal secretion of the pancreatic lipase-related protein 2 present in goat seminal plasma. Biochim Biophys Acta 1686, 169 180.
12. Fauvel J, Bonnefis MJ, Sarda L, Chap H, Thouvenot JP Douste-Blazy L (1981) Purification of two lipases with high phospholipase A1 activity from guinea-pig pancreas. Biochim Biophys Acta 663, 446 456.
13. De Caro J, Sias B, Grandval P, Ferrato F, Halimi H, Carriere F De Caro A (2004) Characterization of pancreatic lipase-related protein 2 isolated from human pancreatic juice. Biochim Biophys Acta 1701, 89 99.
14. Crenon I, Foglizzo E, Kerfelec B, Verine A, Pignol D, Hermoso J, Bonicel J Chapus C (1998) Pancreatic lipase-related protein type I: a specialized lipase or an inactive enzyme. Protein Eng 11, 135 142.
15. De Caro J, Carriere F, Barboni P, Giller T, Verger R De Caro A (1998) Pancreatic lipase-related protein 1 (PLRP1) is present in the pancreatic juice of several species. Biochim Biophys Acta 1387, 331 341.
16. Lowe ME (2002) The triglyceride lipases of the pancreas. J Lipid Res 43, 2007 2016.
17. Borgstrom B (1975) On the interactions between pancreatic lipase and colipase and the substrate, and the importance of bile salts. J Lipid Res 16, 411 417.
18. Brockman H (2000) Kinetic behavior of the pancreatic lipase-colipase- lipid system. Biochimie 82, 987 995.
19. Andersson L, Carriere F, Lowe ME, Nilsson A Verger R (1996) Pancreatic lipase-related protein 2 but not classical pancreatic lipase hydrolyzes galactolipids. Biochim Biophys Acta 1302, 236 240.
20. Sias B, Ferrato F, Grandval P, Lafont D, Boullanger P, De Caro A, Leboeuf B, Verger R Carriere F (2004) Human pancreatic lipase-related protein 2 is a galactolipase. Biochemistry 43, 10138 10148.
21. Reboul E, Berton A, Moussa M, Kreuzer C, Crenon I Borel P (2006) Pancreatic lipase and pancreatic lipase-related protein 2, but not pancreatic lipase-related protein 1, hydrolyze retinyl palmitate in physiological conditions. Biochim Biophys Acta 1761, 4 10.
22. Sebban-Kreuzer C, Deprez-Beauclair P, Berton A Crenon I (2006) High-level expression of nonglycosylated human pancreatic lipase-related protein 2 in Pichia pastoris. Protein Expr Purif 49, 284 291.
23. Jennens ML Lowe ME (1995) Rat GP-3 is a pancreatic lipase with kinetic properties that differ from colipase-dependent pancreatic lipase. J Lipid Res 36, 2374 2382.
24. Winkler FK, D'Arcy A Hunziker W (1990) Structure of human pancreatic lipase. Nature 343, 771 774.
25. Bourne Y, Martinez C, Kerfelec B, Lombardo D, Chapus C Cambillau C (1994) Horse pancreatic lipase. The crystal structure refined at 2.3 A resolution. J Mol Biol 238, 709 732.
26. van Tilbeurgh H, Egloff MP, Martinez C, Rugani N, Verger R Cambillau C (1993) Interfacial activation of the lipase-procolipase complex by mixed micelles revealed by X-ray crystallography. Nature 362, 814 820.
27. van Tilbeurgh H, Sarda L, Verger R Cambillau C (1992) Structure of the pancreatic lipase-procolipase complex. Nature 359, 159 162.
28. Hermoso J, Pignol D, Kerfelec B, Crenon I, Chapus C Fontecilla-Camps JC (1996) Lipase activation by nonionic detergents. The crystal structure of the porcine lipase-colipase-tetraethylene glycol monooctyl ether complex. J Biol Chem 271, 18007 18016.
29. Pignol D, Hermoso J, Kerfelec B, Crenon I, Chapus C Fontecilla-Camps JC (1998) The lipase/colipase complex is activated by a micelle: neutron crystallographic evidence. Chem Phys Lipids 93, 123 129.
30. Roussel A, de Caro J, Bezzine S, Gastinel L, de Caro A, Carriere F, Leydier S, Verger R Cambillau C (1998) Reactivation of the totally inactive pancreatic lipase RP1 by structure-predicted point mutations. Proteins 32, 523 531.
31. Roussel A, Yang Y, Ferrato F, Verger R, Cambillau C Lowe M (1998) Structure and activity of rat pancreatic lipase-related protein J Biol Chem 273, 32121 32128.
32. Jayne S, Kerfelec B, Foglizzo E, Granon S, Hermoso J, Chapus C Crenon I (2002) Activation of horse PLRP2 by bile salts does not require colipase. Biochemistry 41, 8422 8428.
33. Crenon I, Jayne S, Kerfelec B, Hermoso J, Pignol D Chapus C (1998) Pancreatic lipase-related protein type 1: a double mutation restores a significant lipase activity. Biochem Biophys Res Commun 246, 513 517.
34. Bezzine S, Roussel A, de Caro J, Gastinel L, de Caro A, Carriere F, Leydier S, Verger R Cambillau C (1998) An inactive pancreatic lipase-related protein is activated into a triglyceride-lipase by mutagenesis based on the 3-D structure. Chem Phys Lipids 93, 103 114.
35. Carriere F, Thirstrup K, Hjorth S, Ferrato F, Nielsen PF, Withers-Martinez C, Cambillau C, Boel E, Thim L Verger R (1997) Pancreatic lipase structure-function relationships by domain exchange. Biochemistry 36, 239 248.
36. Yang Y Lowe ME (2000) The open lid mediates pancreatic lipase function. J Lipid Res 41, 48 57.
37. Gargouri Y, Bensalah A, Douchet I Verger R (1995) Kinetic behaviour of pancreatic lipase in five species using emulsions and monomolecular films of synthetic glycerides. Biochim Biophys Acta 1257, 223 229.
38. Wong H, Davis RC, Nikazy J, Seebart KE Schotz MC (1991) Domain exchange: characterization of a chimeric lipase of hepatic lipase and lipoprotein lipase. Proc Natl Acad Sci USA 88, 11290 11294.
39. Rietsch J, Pattus F, Desnuelle P Verger R (1977) Further studies of mode of action of lipolytic enzymes. J Biol Chem 252, 4313 4318.
40. Chahinian H, Bezzine S, Ferrato F, Ivanova MG, Perez B, Lowe ME Carriere F (2002) The beta 5′ loop of the pancreatic lipase C2-like domain plays a critical role in the lipase-lipid interactions. Biochemistry 41, 13725 13735.
41. Miled N, Berti-Dupuis L, Riviere M, Carriere F Verger R (2003) In vitro lipolysis by human pancreatic lipase is specifically abolished by its inactive forms. Biochim Biophys Acta 1645, 241 246.
42. Ayvazian L, Kerfelec B, Granon S, Foglizzo E, Crenon I, Dubois C Chapus C (2001) The lipase C-terminal domain. A novel unusual inhibitor of pancreatic lipase activity. J Biol Chem 276, 14014 14018.
43. Rouard M, Sari H, Nurit S, Entressangles B Desnuelle P (1978) Inhibition of pancreatic lipase by mixed micelles of diethyl p-nitrophenyl phosphate and bile salts. Biochim Biophys Acta 530, 227 235.
44. Mancheno JM, Jayne S, Kerfelec B, Chapus C, Crenon I Hermoso JA (2004) Crystallization of a proteolyzed form of the horse pancreatic lipase-related protein 2: structural basis for the specific detergent requirement. Acta Crystallogr D Biol Crystallogr 60, 2107 2109.
45. Freie AB, Ferrato F, Carriere F Lowe ME (2006) Val-407 and Ile-408 in the beta5′-loop of pancreatic lipase mediate lipase-colipase interactions in the presence of bile salt micelles. J Biol Chem 281, 7793 7800.
46. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680 685.
47. Burnette WN (1981) 'Western blotting': electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal Biochem 112, 195 203.