The Vietnamese khin population harbors particular N-acetyltransferase 2 allele frequencies [2]

Clinical Chemistry

Volumn 53, Issue 11, 2007, Pages 1977-1979

  Cavaco, Isa ^a   Asimus, Sara ^b   Peyrard Janvid, Myriam ^c   Ferreira, Pedro E ^a,d   Veiga, M Isabel ^a,d   Hai, Trinh Ngoc ^e   Ribeiro, Vera ^a   Ashton, Michael ^b   Gil, J Pedro ^a,d  

^a UNIVERSITY OF ALGARVE   (Portugal)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

^d KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^e National Institute of Malariology Parasitology and Entomology Hanoi   (Viet Nam)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; ISONIAZID;

ACETYLATOR PHENOTYPE; ADULT; ALLELE; ETHNIC GROUP; FEMALE; GENE FREQUENCY; GENOTYPE; HUMAN; LETTER; MALE; NORMAL HUMAN; SINGLE NUCLEOTIDE POLYMORPHISM; VIET NAM;

ADOLESCENT; ADULT; ARYLAMINE N-ACETYLTRANSFERASE; ASIAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE FREQUENCY; HUMANS; MALE; MIDDLE AGED; VIETNAM;

EID: 35649010335     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2007.092684     Document Type: Letter

References (5)

1. Global tuberculosis control: surveillance, planning, financing. WHO report 2006. Geneva, World Health Organization (WHO/HTM/TB/2006.362).
2. Kukongviriyapan V, Prawan A, Tassaneyakul W, Aiemsa-Ard J, Warasiha B. Arylamine N-acetyltransferase-2 genotypes in the Thai population. Br J Clin Pharmacol 2003;55:278-81.
3. Wen X, Wang JS, Neuvonen PJ, Backman JT. Isoniazid is a mechanism-based inhibitor of cytochrome P450 1A2, 2A6, 2C19 and 3A4 isoforms in human liver microsomes. Eur J Clin Pharmacol 2002;57:799-804.
4. Donald PR, Parkin DP, Seifart HI, Schaaf HS, van Helden PD, Werely CJ, et al. The influence of dose and N-acetyltransferase-2 (NAT2) genotype and phenotype on the pharmacokinetics and pharmacodynamics of isoniazid. Eur J Clin Pharmacol 2007;63:633-9.
5. Gumbo T, Louie A, Liu W, Brown D, Ambrose PG, Bhavnani SM, et al. Isoniazid bactericidal activity and resistance emergence: integrating pharmacodynamics and pharmacogenomics to predict efficacy In different ethnic populations, Antimicrob Agents Chemother 2007;51:2329-36.