Sublingual immunotherapy efficacy in patients with atopic dermatitis and house dust mites sensitivity: A prospective pilot study

Current Medical Research and Opinion

Volumn 23, Issue 10, 2007, Pages 2503-2506

  Cadario, Gianni ^a   Galluccio, Antonia G ^b   Pezza, Michele ^b   Appino, Antonella ^a   Milani, Massimo ^c,e   Pecora, Silvia ^c   Mastrandrea, Fulvio ^d  

^a MOLINETTE HOSPITAL   (Italy)

^b FATEBENEFRATELLI HOSPITAL   (Italy)

^c Medical Department   (Italy)

^d SS Annunziata Hospital   (Italy)

^e ALK Abellò Italy ^*  (Italy)

Author keywords

Atopic dermatitis; House dust mite sensitisation; Sublingual immunotherapy

Indexed keywords

ALLERGEN; ANTIHISTAMINIC AGENT; CALCINEURIN INHIBITOR; CORTICOSTEROID DERIVATIVE; DERMATOPHAGOIDES FARINAE EXTRACT; HOUSE DUST ALLERGEN; IMMUNOGLOBULIN E; IMMUNOSUPPRESSIVE AGENT; SLITONE; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; ASTHMA; ATOPIC DERMATITIS; CLINICAL TRIAL; CONTROLLED STUDY; DEMOGRAPHY; DISEASE SEVERITY; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; FEMALE; HOUSE DUST ALLERGY; HUMAN; IMMUNOTHERAPY; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PILOT STUDY; SCHOOL CHILD; STUDENT T TEST; UNSPECIFIED SIDE EFFECT;

ADMINISTRATION, SUBLINGUAL; ADOLESCENT; ADRENAL CORTEX HORMONES; ADULT; ANIMALS; CHILD; CHILD, PRESCHOOL; DERMATITIS, ATOPIC; FEMALE; HISTAMINE H1 ANTAGONISTS; HUMANS; IMMUNOTHERAPY; MALE; MIDDLE AGED; MITES; PILOT PROJECTS; PROSPECTIVE STUDIES;

EID: 35648968140     PISSN: 03007995     EISSN: None     Source Type: Journal    
DOI: 10.1185/030079907X226096     Document Type: Article

References (15)

1. Adkis C, Akdis M, Bieber T. Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunonology/American Academy of Allergy, Asthma and Immunology/PRACTALL consensus report. J Allergy Clin Immunol 2006;118:152-69
2. Williams HC, Strachan DP. The natural history of childhood eczema: observation from British 1958 birth cohort study. Br J Dermatol 1998;139:834-9
3. Illi S, von Mutius E. The natural course of atopic dermatitis from birth to age 7 years and the association with asthma. J Allergy Clin Immunol 2004;113:925-31
4. Schafer T, Heinrich J. Association between severity of atopic eczema and degree of sensitization to aeroallergens in schoolchildren. J Allergy Clin Immunol 1999;104:1280-4
5. Adinoff AD. Atopic dermatitis and aeroallergen contact sensitivity. J Allergy Clin Immunol 1988;81:736-42
6. Novak N, Bieber T. Allergic and non-allergic forms of atopic diseases. J Allergy Clin Immunol 2003;112:252-62
7. Mastrandrea F. The potential role of allergen-specific sublingual immunotherapy in atopic dermatitis. Am J Clin Dermatol 2004;5:281-94
8. Werfel T, Breuer K, Rueff F. Usefulness of specific immunotherapy in patients with atopic dermatitis and allergic sensitization to house dust mites: a multi-center, randomized, dose-response study. Allergy 2006;61:201-5
9. Bousquet J. Sublingual immunotherapy: validated. Allergy 2006;61:5-6
10. Hanafin J, Raijka G. Diagnostic features of atopic dermatitis. Acta Derm Venereol Suppl 1980;92:44-7
11. Anon. Severity scoring of atopic dermatitis: the SCORAD index. Consensus report of European Task Force on Atopic Dermatitis. Dermatology 1993;186:23-31
12. Anon. Worldwide variation in prevalence of symptoms of asthma allergic rhinoconjunctivitis and atopic eczema: ISAAC. Lancet 1998;351:1225-32
13. Durham S. Tradition and innovation: finding the right balance. J Allergy Clin Immunol 2007;119:792-5
14. Pajno G, Caminiti L. Sublingual immunotherapy in mite-sensitized children with atopic dermatitis: a randomized double blind, placebo-controlled study. J Allergy Clin Immunol 2007 [in press]
15. Weber M, Petry V. Evaluating the relation between pruritus, serum IgE levels and severity of clinical manifestations in atopic dermatitis patients. An Bras Dermatol 2005;80:245