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Volumn 66, Issue SUPPL. 3, 2007, Pages

New therapies for sepsis: Focus on the interleukin (IL)12 family member IL27

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 27; PROTEIN P28;

EID: 35648965333     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.2007.078337     Document Type: Conference Paper
Times cited : (12)

References (12)
  • 1
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    • IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells
    • Pflanz S, Timans JC, Cheung J, Rosales R, Kanzler H, Gilbert J, et al. IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells. Immunity 2002;16:779-90.
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    • Pflanz, S.1    Timans, J.C.2    Cheung, J.3    Rosales, R.4    Kanzler, H.5    Gilbert, J.6
  • 2
    • 0030067819 scopus 로고    scopus 로고
    • A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes
    • Devergne O, Hummel M, Koeppen H, Le Beau MM, Nathanson EC, Kieff E, et al. A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes. J Virol 1996;70:1143-53.
    • (1996) J Virol , vol.70 , pp. 1143-1153
    • Devergne, O.1    Hummel, M.2    Koeppen, H.3    Le Beau, M.M.4    Nathanson, E.C.5    Kieff, E.6
  • 3
    • 10744222574 scopus 로고    scopus 로고
    • WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27
    • Pflanz S, Hibbert L, Mattson J, Rosales R, Vaisberg E, Bazan JF, et al. WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27. J Immunol 2004;172:2225-31.
    • (2004) J Immunol , vol.172 , pp. 2225-2231
    • Pflanz, S.1    Hibbert, L.2    Mattson, J.3    Rosales, R.4    Vaisberg, E.5    Bazan, J.F.6
  • 4
    • 4644225089 scopus 로고    scopus 로고
    • An indispensable role for STAT1 in IL-27-induced T-bet expression but not proliferation of naive CD4+ T cells
    • Kamiya S, Owaki T, Morishima N, Fukai F, Mizuguchi J, Yoshimoto T. An indispensable role for STAT1 in IL-27-induced T-bet expression but not proliferation of naive CD4+ T cells. J Immunol 2004;173:3871-7.
    • (2004) J Immunol , vol.173 , pp. 3871-3877
    • Kamiya, S.1    Owaki, T.2    Morishima, N.3    Fukai, F.4    Mizuguchi, J.5    Yoshimoto, T.6
  • 5
    • 20044378485 scopus 로고    scopus 로고
    • EBV-induced gene 3 transcription is induced by TLR signaling in primary dendritic cells via NF-kappa B activation
    • Wirtz S, Becker C, Fantini MC, Nieuwenhuis EE, Tubbe I, Galle PR, et al. EBV-induced gene 3 transcription is induced by TLR signaling in primary dendritic cells via NF-kappa B activation. J Immunol 2005;174:2814-24.
    • (2005) J Immunol , vol.174 , pp. 2814-2824
    • Wirtz, S.1    Becker, C.2    Fantini, M.C.3    Nieuwenhuis, E.E.4    Tubbe, I.5    Galle, P.R.6
  • 6
    • 6344274850 scopus 로고    scopus 로고
    • The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity
    • Artis D, Villarino A, Silverman M, He W, Thornton EM, Mu S, et al. The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity. J Immunol 2004;173:5626-34.
    • (2004) J Immunol , vol.173 , pp. 5626-5634
    • Artis, D.1    Villarino, A.2    Silverman, M.3    He, W.4    Thornton, E.M.5    Mu, S.6
  • 7
    • 0345570521 scopus 로고    scopus 로고
    • The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection
    • Villarino A, Hibbert L, Lieberman L, Wilson E, Mak T, Yoshida H, et al. The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection. Immunity 2003;19:645-55.
    • (2003) Immunity , vol.19 , pp. 645-655
    • Villarino, A.1    Hibbert, L.2    Lieberman, L.3    Wilson, E.4    Mak, T.5    Yoshida, H.6
  • 10
    • 33746931178 scopus 로고    scopus 로고
    • Protection from lethal septic peritonitis by neutralizing the biological function of interleukin 27
    • Wirtz S, Tubbe I, Galle PR, Schild HJ, Birkenbach M, Blumberg RS, et al. Protection from lethal septic peritonitis by neutralizing the biological function of interleukin 27. J Exp Med 2006;203:1875-81.
    • (2006) J Exp Med , vol.203 , pp. 1875-1881
    • Wirtz, S.1    Tubbe, I.2    Galle, P.R.3    Schild, H.J.4    Birkenbach, M.5    Blumberg, R.S.6
  • 11
    • 34247574160 scopus 로고    scopus 로고
    • Pathogenesis and sepsis caused by organisms potentially utilized as biologic weapons: Opportunities for targeted intervention
    • in press
    • Hepburn MJ, Purcell BK, Paragas J. Pathogenesis and sepsis caused by organisms potentially utilized as biologic weapons: opportunities for targeted intervention. Curr Drug Targets, 2007, in press.
    • (2007) Curr Drug Targets
    • Hepburn, M.J.1    Purcell, B.K.2    Paragas, J.3
  • 12
    • 34247403460 scopus 로고    scopus 로고
    • Sepsis since the discovery of Toll-like receptors: Disease concepts and therapeutic opportunities
    • in press
    • Leaver SK, Finney SJ, Burke-Gaffney A, Evans TW. Sepsis since the discovery of Toll-like receptors: disease concepts and therapeutic opportunities. Crit Care Med, 2007, in press.
    • (2007) Crit Care Med
    • Leaver, S.K.1    Finney, S.J.2    Burke-Gaffney, A.3    Evans, T.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.