Antibody-mediated protection through cross-reactivity introduces a fungal heresy into immunological dogma

Infection and Immunity

Volumn 75, Issue 11, 2007, Pages 5074-5078

  Casadevall, Arturo ^a   Pirofski, Liise Anne ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; ASPARTIC PROTEINASE; BETA GLUCAN; CELL MEMBRANE PROTEIN; GLUCOSYLCERAMIDE; GLUCURONOXYLOMANNAN; GLYCOPROTEIN; HEAT SHOCK PROTEIN 90; HISTONE LIKE NUCLEOID STRUCTURING PROTEIN; IMMUNOGLOBULIN; IMMUNOGLOBULIN ANTIBODY; IMMUNOGLOBULIN M; MANNOPROTEIN; MELANIN; MONOCLONAL ANTIBODY; POLYSACCHARIDE;

ANTIBODY RESPONSE; ASCOMYCETES; ASPERGILLUS FUMIGATUS; BACTERIAL CELL WALL; CANDIDA ALBICANS; CROSS REACTION; CRYPTOCOCCUS NEOFORMANS; HISTOPLASMA CAPSULATUM; HYPOGAMMAGLOBULINEMIA; IMMUNE RESPONSE; IMMUNITY; IMMUNIZATION; MYCOSIS; NONHUMAN; NOTE; PATHOGENESIS; PNEUMOCYSTIS; PRIORITY JOURNAL;

ANTIBODIES, FUNGAL; CROSS REACTIONS; FUNGAL VACCINES; FUNGI; HUMANS; MYCOSES;

EID: 35648964704     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.01001-07     Document Type: Note

References (45)

1. Alugupalli, K. R., R. M. Gerstein, J. Chen, E. Szomolanyi-Tsuda, R. T. Woodland, and J. M. Leong. 2003. The resolution of relapsing fever borreliosis requires IgM and is concurrent with expansion of B1b lymphocytes. J. Immunol. 170:3819-3827.
2. Alviano, D. S., A. J. Franzen, L. R. Travassos, C. Holandino, S. Rozental, R. Ejzemberg, C. S. Alviano, and M. L. Rodrigues. 2004. Melanin from Fonsecaea pedrosoi induces production of human antifungal antibodies and enhances the antimicrobial efficacy of phagocytes. Infect. Immun. 72:229-237.
3. Boes, M., A. P. Prodeus, T. Schmidt, M. C. Carroll, and J. Chen. 1998. A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infection. J. Exp. Med. 188:2381-2386.
4. Brown, J. S., T. Hussell, S. M. Gilliland, D. W. Holden, J. C. Paton, M. R. Ehrenstein, M. J. Walport, and M. Botto. 2002. The classical pathway is the dominant complement pathway required for innate immunity to Streptococcus pneumoniae infection in mice. Proc. Natl. Acad. Sci. USA 99:16969-16974.
5. Casadevall, A. 1995. Antibody immunity and invasive fungal infections. Infect. Immun. 63:4211-4218.
6. Casadevall, A., and L. A. Pirofski. 2004. New concepts in antibody-mediated immunity. Infect. Immun. 72:6191-6196.
7. Chaturvedi, A. K., A. Kavishwar, G. B. Shiva Keshava, and P. K. Shukla. 2005. Monoclonal immunoglobulin G1 directed against Aspergillus fumigatus cell wall glycoprotein protects against experimental murine aspergillosis. Clin. Diagn. Lab Immunol. 12:1063-1068.
8. De Bernardis, F., M. Boccanera, D. Adriani, E. Spreghini, G. Santoni, and A. Cassone. 1997. Protective role of antimannan and anti-aspartyl proteinase antibodies in an experimental model of Candida albicans vaginitis in rats. Infect. Immun. 65:3399-3405.
9. De Bernardis, F., H. Liu, R. O'Mahony, R. La Valle, S. Bartollino, S. Sandini, S. Grant, N. Brewis, I. Tomlinson, R. C. Basset, J. Holten, I. M. Roitt, and A. Cassone. 2007. Human domain antibodies against virulence traits of Candida albicans inhibit fungus adherence to vaginal epithelium and protect against experimental vaginal candidiasis. J. Infect. Dis. 195:149-157.
10. Dromer, F., J. Charreire, A. Contrepois, C. Carhon, and P. Yeni. 1987. Protection of mice against experimental cryptococcosis by anti-Cryptococcus neoformans monoclonal antibody. Infect. Immun. 55:749-752.
11. Fleuridor, R., Z. Zhong, and L. Pirofski. 1998. A human IgM monoclonal antibody prolongs survival of mice with lethal cryptococcosis. J. Infect. Dis. 178:1213-1216.
12. Gigliotti, F., C. G. Haidaris, T. W. Wright, and A. G. Harmsen. 2002. Passive intranasal monoclonal antibody prophylaxis against murine Pneumocystis carinii pneumonia. Infect. Immun. 70:1069-1074.
13. Han, Y., and J. E. Cutler. 1995. Antibody response that protects against disseminated candidiasis. Infect. Immun. 63:2714-2719.
14. Han, Y., T. Kanbe, R. Cherniak, and J. E. Cutler. 1997. Biochemical characterization of Candida albicans epitopes that can elicit protective and non-protective antibodies. Infect. Immun. 65:4100-4107.
15. Han, Y., T. R. Kozel, M. X. Zhang, R. S. MacGill, M. C. Carroll, and J. E. Cutler. 2001. Complement is essential for protection by an IgM and an IgG3 monoclonal antibody against experimental, hematogenously disseminated candidiasis. J. Immunol. 167:1550-1557.
16. Han, Y., R. P. Morrison, and J. E. Cutler. 1998. A vaccine and monoclonal antibodies that enhance mouse resistance to Candida albicans vaginal infection. Infect. Immun. 66:5771-5776.
17. Ro, J. I., J. M. Lyons, T. B. Hong, D. Tamae, Y. K. Liu, S. P. Wilczynski, and M. Kalkum. 2006. Vaccinations with recombinant variants of Aspergillus fumigatus allergen Asp f 3 protect mice against invasive aspergillosis. Infect. Immun. 74:5075-5084.
18. Jayasekera, J. P., E. A. Moseman, and M. C. Carroll. 2007. Natural antibody and complement mediate neutralization of influenza virus in the absence of prior immunity. J. Virol. 81:3487-3494.
19. Kondori, N., L. Edebo, and I. Mattsby-Baltzer. 2004. Circulating beta (1-3) glucan and immunoglobulin G subclass antibodies to Candida albicans cell wall antigens in patients with systemic candidiasis. Clin. Diagn. Lab. Immunol. 11:344-350.
20. Larsen, R. A., P. G. Pappas, J. R. Perfect, J. A. Aberg, A. Casadevall, G. A. Cloud, R. James, S. Filler, and W. E. Dismukes. 2005. A phase I evaluation of the safety and pharmacodynamic activity of a murine-derived monoclonal antibody 18B7 in subjects with treated cryptococcal meningitis. Antimicrob. Agents Chemother. 49:952-958.
21. Maitta, R., K. Datta, Q. Chang, R. Luo, B. Witover, K. Subramanian, and L. Pirofski. 2004. Protective and nonprotective human immunoglobulin M monoclonal antibodies to Cryptococcus neoformans glucuronoxylomannan manifest different specificities and gene usage profiles. Infect. Immun. 72: 4810-4818.
22. Martinez, L. R., and A. Casadevall. 2005. Specific antibody can prevent fungal biofilm formation and this effect correlates with protective efficacy. Infect. Immun. 73:6350-6362.
23. Matthews, R. C., G. Rigg, S. Hodgetts, T. Carter, C. Chapman, C. Gregory, C. Illidge, and J. Burnie. 2003. Preclinical assessment of the efficacy of Mycograb, a human recombinant antibody against fungal HSP90. Antimicrob. Agents Chemother. 47:2208-2216.
24. Moragues, M. D., M. J. Omaetxebarria, N. Elguezabal, M. J. Sevilla, S. Conti, L. Polonelli, and J. Ponton. 2003. A monoclonal antibody directed against a Candida albicans cell wall mannoprotein exerts three anti-C. albicans activities. Infect. Immun. 71:5273-5279.
25. Mukherjee, J., G. Nussbaum, M. D. Scharff, and A. Casadevall. 1995. Protective and non-protective monoclonal antibodies to Cryptococcus neoformans originating from one B-cell. J. Exp. Med. 181:405-409.
26. Mukherjee, J., M. D. Scharff, and A. Casadevall. 1992. Protective murine monoclonal antibodies to Cryptococcus neoformans. Infect. Immun. 60:4534-4541.
27. Nimrichter, L., M. L. Rodrigues, E. G. Rodrigues, and L. R. Travassos. 2005. The multitude of targets for the immune system and drug therapy in the fungal cell wall. Microbes Infect. 7:789-798.
28. Nosanchuk, J. D., J. N. Steenbergen, L. Shi, G. S. Deepe, Jr., and A. Casadevall. 2003. Antibodies to a cell surface histone-like protein protect against Histoplasma capsulatum. J. Clin. Investig. 112:1164-1175.
29. Pachl, J., P. Svoboda, F. Jacobs, B. van der Hoven, P. Spronk, G. Masterson, M. Malbrain, M. Aoun, J. Garbino, J. Takala, L. Drgona, J. Burnie, and R. Matthews. 2006. A randomized, blinded, multicenter trial of lipid-associated amphotericin B alone versus in combination with an antibody-based inhibitor of heat shock protein 90 in patients with invasive candidiasis. Clin. Infect. Dis. 42:1404-1413.
30. Pappagianis, D. 2001. Serologic studies in coccidioidomycosis. Semin. Respir. Infect. 16:242-250.
31. Parra, C., J. M. Gonzalez, E. Castaneda, and S. Fiorentino. 2005. Antiglucuronoxylomannan IgG1 specific antibodies production in Cryptococcus neoformans resistant mice. Biomedica 25:110-119.
32. Polonelli, L., F. De Bernardis, S. Conti, M. Boccanera, W. Magliani, M. Gerloni, C. Cantelli, and A. Cassone. 1996. Human natural yeast killer toxin-like candidacidal antibodies. J. Immunol. 156:1880-1885.
33. Polonelli, L., N. Seguy, S. Conti, M. Gerloni, D. Bertolotti, C. Cantelli, W. Magliani, and J. C. Cailliez. 1997. Monoclonal yeast killer toxin-like candidacidal anti-idiotypic antibodies. Clin. Diagn. Lab Immunol. 4:142-146.
34. Rachini, A., D. Pietrella, P. Lupo, A. Torosantucci, P. Chiani, C. Bromuro, C. Proietti, F. Bistoni, A. Cassone, and A. Vecchiarelli. 2007. An anti-β-glucan monoclonal antibody inhibits growth and capsule formation of Cryptococcus neoformans in vitro and exerts therapeutic, anticryptococcal activity in vivo. Infect. Immun. 75:5085-5094.
35. Rajan, B., T. Ramalingam, and T. V. Rajan. 2005. Critical role for IgM in host protection in experimental filarial infection. J. Immunol. 175:1827-1833.
36. Rodrigues, M. L., L. R. Travassos, K. R. Miranda, A. J. Franzen, S. Rozental, W. De Souza, C. S. Alviano, and E. Barreto-Bergter. 2000. Human antibodies against a purified glucosylceramide from Cryptococcus neoformans inhibit cell budding and fungal growth. Infect. Immun. 68:7049-7060.
37. Rosas, A. L., J. D. Nosanchuk, and A. Casadevall. 2001. Passive immunization with melanin-binding monoclonal antibodies prolongs survival in mice with lethal Cryptococcus neoformans infection. Infect. Immun. 69:3410-3412.
38. Sanford, J. E., D. M. Lupan, A. M. Schlagetter, and T. R. Kozel. 1990. Passive immunization against Cryptococcus neoformans with an isotype-switch family of monoclonal antibodies reactive with cryptococcal polysaccharide. Infect. Immun. 58:1919-1923.
39. Seguy, N., J. C. Cailliez, P. Delcourt, S. Conti, D. Camus, E. Dei-Cas, and L. Polonelli. 1997. Inhibitory effect of human natural yeast killer toxin-like candidacidal antibodies on Pneumocystis carinii. Mol. Med. 3:544-552.
40. Sevilla, M. J., B. Robledo, A. Rementeria, M. D. Moragues, and J. Ponton. 2006. A fungicidal monoclonal antibody protects against murine invasive candidiasis. Infect. Immun. 74:3042-3045.
41. Shapiro, S., D. O. Beenhouwer, M. Feldmesser, C. Taborda, M. C. Carroll, A. Casadevall, and M. D. Scharff. 2002. Immunoglobulin G monoclonal antibodies to Cryptococcus neoformans protect mice deficient in complement component C3. Infect. Immun. 70:2598-2604.
42. Torosantucci, A., C. Bromuro, P. Chiani, F. De Bernardis, F. Berti, C. Galli, F. Norelli, C. Bellucci, L. Polonelli, P. Costantino, R. Rappuoli, and A. Cassone. 2005. A novel glyco-conjugate vaccine against fungal pathogens. J. Exp. Med. 202:597-606.
43. Wells, J., C. G. Haidaris, T. W. Wright, and F. Gigliotti. 2006. Active immunization against Pneumocystis carinii with a recombinant P. carinii antigen. Infect. Immun. 74:2446-2448.
44. Wells, J., C. G. Haidaris, T. W. Wright, and F. Gigliotti. 2006. Complement and Fc function are required for optimal antibody prophylaxis against Pneumocystis carinii pneumonia. Infect. Immun. 74:390-393.
45. Young, S. H., G. R. Ostroff, P. C. Zeidler-Erdely, J. R. Roberts, J. M. Antonini, and V. Castranova. 2007. A comparison of the pulmonary inflammatory potential of different components of yeast cell wall. J. Toxicol. Environ. Health Part A 70:1116-1124.