Repair of spinal cord transection and its effects on muscle mass and myosin heavy chain isoform phenotype

Journal of Applied Physiology

Volumn 103, Issue 5, 2007, Pages 1808-1814

  Lee, Yu Shang ^a,b   Lin, Ching Yi ^a   Caiozzo, Vincent J ^a   Robertson, Richard T ^a   Yu, Jen ^a   Lin, Vernon W ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VA LONG BEACH HEALTHCARE SYSTEM   (United States)

Author keywords

Acidic fibroblast growth factor; Peripheral nerve graft; Spinal cord injury

Indexed keywords

ACIDIC FIBROBLAST GROWTH FACTOR; MYOSIN HEAVY CHAIN; SEROTONIN;

ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; FEMALE; IMMUNOHISTOCHEMISTRY; LOCOMOTION; MUSCLE CELL; MUSCLE MASS; NERVE GRAFT; NONHUMAN; PHENOTYPE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SOLEUS MUSCLE; SPINAL CORD TRANSSECTION;

ANIMALS; BODY WEIGHT; DISEASE MODELS, ANIMAL; FEMALE; FIBROBLAST GROWTH FACTOR 1; INTERCOSTAL NERVES; MOTOR ACTIVITY; MUSCLE FIBERS; MUSCLE FIBERS, SLOW-TWITCH; MUSCLE, SKELETAL; MYOSIN HEAVY CHAINS; NERVE REGENERATION; ORGAN SIZE; PHENOTYPE; PROTEIN ISOFORMS; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; SEROTONIN; SPINAL CORD INJURIES; TIME FACTORS;

EID: 35648963044     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00588.2007     Document Type: Article

References (26)

1. Barritt AW, Davies M, Marchand F, Hartley R, Grist J, Yip P, McMahon SB, Bradbury EJ. Chondroitinase ABC promotes sprouting of intact and injured spinal systems after spinal cord injury. J Neurosci 26: 10856-10867, 2006.
2. Blits B, Dijkhuizen PA, Boer GJ, Verhaagen J. Intercostal nerve implants transduced with an adenoviral vector encoding neurotrophin-3 promote regrowth of injured rat corticospinal tract fibers and improve hindlimb function. Exp Neurol 164: 25-37, 2001.
3. Bradbury EJ, Moon LD, Popat RJ, King VR, Bennett GS, Patel PN, Fawcett JW, McMahon SB. Chondroitinase ABC promotes functional recovery after spinal cord injury. Nature 416: 636-640, 2002.
4. Caiozzo VJ. Plasticity of skeletal muscle phenotype: mechanical consequences. Muscle Nerve 26: 740-768, 2002.
5. Caiozzo VJ, Baker MJ, Baldwin KM. Novel transitions in MHC isoforms: separate and combined effects of thyroid hormone and mechanical unloading. J Appl Physiol 85: 2237-2248, 1998.
6. Caiozzo VJ, Baker MJ, Huang K, Chou H, Wu YZ, Baldwin KM. Single-fiber myosin heavy chain polymorphism: how many patterns and what proportions? Am J Physiol Regul Integr Comp Physiol 285: R570-R580, 2003.
7. Cheng H, Cao Y, Olson L. Spinal cord repair in adult paraplegic rats: partial restoration of hind limb function. Science 273: 510-513, 1996.
8. Cooper RN, Feraboli-Lohnherr D, Butler-Browne G, Orsal D, Gimenez y Ribotta M, Privat A. Intraspinal injection of embryonic neurons maintains muscle phenotype in adult chronic spinal rats. J Neurosci Res 46: 324-329, 1996.
9. David S, Aguayo A. Axonal elongation into peripheral nerve system "bridges" after central nervous system injury in adult rats. Science 214: 931-933, 1981.
10. Edgerton VR, Roy RR, Allen DL, Monti RJ. Adaptations in skeletal muscle disuse or decreased-use atrophy. Am J Phys Med Rehabil 81: S127-S147, 2002.
11. Fraidakis MJ, Spenger C, Olson L. Partial recovery after treatment of chronic paraplegia in rat. Exp Neurol 188: 33-42, 2004.
12. Golding JD, MacDonald ST, Juurlink BH, Rosser BW. The effect of glutamine on locomotor performance and skeletal muscle myosins following spinal cord injury in rats. J Appl Physiol 101: 1045-1052, 2006.
13. Grandpré T, Strittmatter SM. Nogo: a molecular determinant of axonal growth and regeneration. Neuroscientist 7: 377-386, 2001.
14. Iwashita Y, Kawaguchi S, Murata M. Restoration of function by replacement of spinal cord segments in the rat. Nature 367: 167-170, 1994.
15. Khan T, Dauzvardis M, Sayers S. Carbon filament implants promote axonal growth across the transected rat spinal cord. Brain Res 541: 139-145, 1991.
16. Lee YS, Hsiao I, Lin V. Peripheral nerve graft and aFGF restore partial hindlimb function in adult paraplegic rats. J Neurotrauma 19: 1203-1216, 2002.
17. Lee YS, Lin CY, Robertson RT, Hsiao I, Lin VW. Motor recovery and anatomical evidence of axonal regrowth in spinal cord-repaired adult rats. J Neuropathol Exp Neurol 63: 233-245, 2004.
18. Lee YS, Lin CY, Robertson RT, Yu J, Deng XM, Hsiao I, Lin VW. Re-growth of catecholaminergic fibers and protection of cholinergic spinal cord neurons in spinal repaired rats. Eur J Neurosci 23: 693-702, 2006.
19. Lee YS, Sindhu RK, Lin CY, Ehdaie A, Lin VW, Vaziri ND. Effects of nerve graft on nitric oxide synthase, NAD(P)H oxidase, and antioxidant enzymes in chronic spinal cord injury. Free Radic Biol Med 36: 330-339, 2004.
20. Levi AD, Dancausse H, Li X, Duncan S, Horkey L, Oliviera M. Peripheral nerve grafts promoting central nervous system regeneration after spinal cord injury in the primate. J Neurosurg 96: 197-205, 2002.
21. Novikova LN, Novikov LN, Kellerth JO. Biopolymers and biodegrad-able smart implants for tissue regeneration after spinal cord injury. Curr Opin Neurol 16: 711-715, 2003.
22. Slawinska U, Majczynski R, Djavadian R. Recovery of hindlimb motor functions after spinal cord transection is enhanced by grafts of the embryonic raphe nuclei. Exp Brain Res 132: 27-38, 2000.
23. Talmadge RJ, Roy RR, Edgerton VR. Prominence of myosin heavy chain hybrid fibers in soleus muscle of spinal cord-transected rats. J Appl Physiol 78: 1256-1265, 1995.
24. Talmadge RJ, Roy RR, Caiozzo VJ, Edgerton VR. Mechanical properties of rat soleus after long-term spinal cord transection. J Appl Physiol 93: 1487-1497, 2002.
25. Tsai EC, Krassioukov AV, Tator CH. Corticospinal regeneration into lumbar grey matter correlates with locomotor recovery after complete spinal cord transection and repair with peripheral nerve grafts, fibroblast growth factor 1, fibrin glue, and spinal fusion. J Neuropathol Exp Neurol 64: 230-244, 2005.
26. Yiu G, He Z. Glial inhibition of CNS axon regeneration. Nat Rev Neurosci 7: 617-627, 2006.