To cut or not to cut: A modeling approach for assessing the role of male circumcision in HIV control

Bulletin of Mathematical Biology

Volumn 69, Issue 8, 2007, Pages 2447-2466

  Podder, C N ^a   Sharomi, O ^a   Gumel, A B ^a   Moses, S ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

ARVs; Backward bifurcation; Condoms; HIV AIDS; Male circumcision; Reproduction number

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

ARTICLE; BIOLOGICAL MODEL; CIRCUMCISION; CONDOM; DISEASE TRANSMISSION; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MALE; MATHEMATICS; SOUTH AFRICA; UTILIZATION REVIEW;

ANTI-HIV AGENTS; CIRCUMCISION, MALE; CONDOMS; FEMALE; HIV INFECTIONS; HUMANS; MALE; MATHEMATICS; MODELS, BIOLOGICAL; SOUTH AFRICA;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 35648941691     PISSN: 00928240     EISSN: 15229602     Source Type: Journal    
DOI: 10.1007/s11538-007-9226-9     Document Type: Article

References (20)

1. Aubert, B., Taljaard, D., Lagrade, E., Sobngwi-Tambekou, J., Sitta, R. et al., 2005. Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: the ANRS 1265 trial. PLoS Med. 2, e298.
2. Bailey, R., Neema, S., Otheno, R., 1999. Sexual behaviors and other HIV risk factors in circumcised and uncircumcised men in Uganda. J. Acquir Immune Defic. Syndr. 22, 294-301.
3. Blower, S., Koelle, K., Mills, J., 2002. Health policy modeling: epidemic control, HIV vaccines, and risky behavior. In: Kaplan, Brookmeyer (Eds.) Qualitative Evaluation of HIV Prevention Programs, pp. 260-289. Yale University Press.
4. Brian, G. Williams, Lioyd-Smith, J.O., Gouws, E., Hankins, C., Getz, W.M., Hargrove, J., de Zoysa, I., Dye, C., Auvert, B., 2006. The potential impact of male circumcision on HIV in sub-Saharan Africa. PLoS Med. 3(7), e262.
5. David, K.R., Weller, S.C., 1999. The effectiveness of condoms in reducing heterosexual transmision of HIV. Fam. Plann. Perspect 31(6), 272-279.
6. Elbasha, E.H., Gumel, A.B., 2006. Theoretical assessment of public health impact of imperfect prophylactic HIV-1 vaccines with therapeutic benefits. Bull. Math. Biol. 68, 577-614.
7. Fink, A., 1986. A possible explanation for heterosexual male infection with AIDS. N. Engl. J. Med. 314, 1167.
8. Gumel, A.B., McCluskey, C.C. et al., 2006. Mathematical study of a staged-progression HIV model with imperfect vaccine. Bull. Math. Biol. 68(8), 2105-2128.
9. Hutchinson, J., 1885. On the influence of circumcision in preventing syphilis. Med. Times Gazette 1, 542-543.
10. Lansky, A., Nakashima, A., Jones, J., 2000. Risk behaviors related to heterosexual transmission from HIV-infected persons. Sex. Transm. Dis. 27, 483-489.
11. Moses, S., Bailey, R.C., Ronald, A.R., 1998. Male circumcision: assessment of health benefits and risks. Sex. Transm. Infect. 74, 368-373.
12. Perelson, A.S., Nelson, P.W., 1999. Mathematical analysis of HIV-1 dynamics in vivo. SIAM Rev. 41(1), 3-44.
13. Robert, C.B., Francis, A.P., Stephen, M., 2001. Male circumcision and HIV prevention: current knowledge and future research directions. Lancet Infect. Dis. 1, 223-231.
14. Report on the global AIDS epidemic: Executive summary, 2006. A UNAIDS 10th anniversary special edition.
15. Siegfried, N., Muller, M., Deeks, J., Volmink, J., Egger, M. et al., 2005. HIV and male circumcision-a systematic review with assessment of the quality of studies. Lancer Infect. Dis. 5, 165-173.
16. USAID 2004. The President's emergency plan for AIDS relief: US five-year Global HIV/AIDS strategy. Available: http://www.usaid.gov/our_work/ global_health/aids/pepfar.html, accessed 25 May 2006.
17. van den Driessche, P., Watmough, J., 2002. Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission. Math. Biosci. 180, 29-48.
18. Weiss, H.A., Quigley, M.A., Hayes, R.J., 2000. Male circumcision and risk of HIV infection in sub-Saharan Africa: a systematic review and meta-analysis. AIDS 14, 2361-2370.
19. WHO, UNAIDS, 2005. Progress on access to anti-retroviral therapy: an update on "3 by 5", p. 34 World Health Organization, Geneva.
20. Wilson, P.A., Binagwaho, A., Ruxin, J., 2005. Combating AIDS in the developing world, p. 276 Earthscan, London.