Synthesis, QSAR and calcium channel antagonist activity of new 1,4-dihydropyridine derivatives containing 1-methy 1-4,5-dichloroimidazolyl substituents

Archiv der Pharmazie

Volumn 340, Issue 10, 2007, Pages 549-556

  Hosseini, Maryam ^a   Miri, Ramin ^b,c,f   Amini, Mohsen ^b   Mirkhani, Hossein ^c   Hemmateenejad, Bahram ^c,d   Ghodsi, Shahram ^e   Alipour, Eskandar ^a   Shafiee, Abbas ^b  

^a ISLAMIC AZAD UNIVERSITY   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d SHIRAZ UNIVERSITY   (Iran)

^e ISLAMIC AZAD UNIVERSITY   (Iran)

^f TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Calcium antagonist; Dichloroimidazole; Dihydropyridine; QSAR analysis

Indexed keywords

1 METHYL 4,5 DICHLOROIMIDAZOLYL DERIVATIVE; 1,4 DIHYDROPYRIDINE DERIVATIVE; CALCIUM CHANNEL BLOCKING AGENT; DIARYL 1,4 DIHYDRO 2,6 DIMETHYL 4 (1 METHYL 4,5 DICHLOROIMIDAZOLE 2 YL) 3,5 PYRIDINEDICARBOXYLATE; DIBENZYL 1,4 DIHYDRO 2,6 DIMETHYL 4 (1 METHYL 4,5 DICHLOROIMIDAZOLE 2 YL) 3,5 PYRIDINE DICARBOXYLATE; DIETHYL 1,4 DIHYDRO 2,6 DIMETHYL 4 (1 METHYL 4,5 DICHLOROIMIDAZOLE 2 YL) 3,5 PYRIDINE DICARBOXYLATE; IMIDAZOLINE DERIVATIVE; NIFEDIPINE; UNCLASSIFIED DRUG;

ARTICLE; DOSE RESPONSE; DRUG MECHANISM; DRUG SYNTHESIS; HUMAN; IC 50; INFRARED SPECTROMETRY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ANIMALS; CALCIUM CHANNEL BLOCKERS; DIHYDROPYRIDINES; GUINEA PIGS; ILEUM; IMIDAZOLES; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MASS SPECTROMETRY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SPECTROPHOTOMETRY, INFRARED;

EID: 35549010699     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200600211     Document Type: Article

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