Big ET-1 processing into vasoactive peptides in arteries and veins

Vascular Pharmacology

Volumn 47, Issue 5-6, 2007, Pages 302-312

  Watts, Stephanie W ^a   Thakali, Keshari ^a   Smark, Chuck ^a   Rondelli, Catherine ^a   Fink, Gregory D ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Artery; ET processing; Vein

Indexed keywords

CHYMASE; ENDOTHELIN 1; ENDOTHELIN CONVERTING ENZYME; ILOMASTAT; MATRIX METALLOPROTEINASE; MINOCYCLINE; PHOSPHORAMIDON;

ANIMAL CELL; ANIMAL TISSUE; AORTA; ARTERY CONSTRICTION; ARTICLE; CAVA VEIN; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MALE; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; RAT; VENOCONSTRICTION; WESTERN BLOTTING; ZYMOGRAPHY;

ANIMALS; AORTA, THORACIC; ASPARTIC ENDOPEPTIDASES; CHYMASES; DIPEPTIDES; ENDOTHELIN-1; GLYCOPEPTIDES; ISOMETRIC CONTRACTION; MALE; MATRIX METALLOPROTEINASES; METALLOENDOPEPTIDASES; MINOCYCLINE; MUSCLE, SMOOTH, VASCULAR; PEPTIDE FRAGMENTS; PHOSPHONIC ACIDS; PROTEASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; TETRAZOLES; VENA CAVA, INFERIOR;

EID: 35548999574     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vph.2007.08.006     Document Type: Article

References (38)

1. Battistini B., Ayach B., Molez S., Blouin A., and Jeng A.Y. Effects of benazepril, an angiotensin converting enzyme inhibitor, combined with CGS 35066, a selective endothelin converting enzyme inhibitor, on arterial blood pressure in normotensive and spontaneously hypertensive rats. Clin. Sci. 103 S48 (2002) 363S-366S
2. Battistini B., Daull P., and Jeng A.Y. CGS 3601, a triple inhibitor of angiotensin converting enzyme, neutral endopeptidase and endothelin converting enzyme. Cardiovasc. Drug Rev. 23 (2005) 317-330
3. Fecteau M.H., Honore J.C., Plante M., Labonte J., Rae G.A., and D'Orleans-Juste P. Endothelin-1 (1-31) is an intermediate in the production of endothelin-1 after big endothelin-1 administration in vivo. Hypertension 46 (2005) 87-92
4. Fernandez-Patron C., Radomski M.W., and Davidge S.T. Vascular matrix metalloproteinase-2 cleaves big endothelin-1 yielding a novel vasoconstrictor. Circ. Res. 85 (1999) 906-911
5. Fernandez-Patron C., Radomski M.W., and Davidge S.T. Role of matrix metalloproteinase-2 in thrombin-induced vasorelaxation of rat mesenteric arteries. Am. J. Physiol. 278 (2000) H1473-H1479
6. Gonzalez-Santiago L., Lopez-Ongil S., Griera M., Rodriguez-Puyol M., and Rodriguez-Puyol D. Regulation of endothelin synthesis by extracellular matrix in human endothelial cells. Kidney Int. 62 (2002) 537-543
7. Guo C., Ju H., Leung D., Massaeli H., Shi M., and Rabinovitch M. A novel vascular smooth muscle chymase is upregulated in hypertensive rats. J. Clin. Invest. 107 (2001) 703-715
8. Harrison V.J., Barnes K., and Turner A.J. Identification of endothelin 1 and big endothelin 1 in secretory vesicles isolated from bovine aortic endothelial cells. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 6344-6348
9. Hisaki K., Matsumura Y., Ikegawa R., Nishiguchi S., Hayashi K., Takaoka M., and Morimoto S. Evidence for phosphoramidon-sensitive conversion of big endothelin-1 to endothelin-1 in isolated rat mesenteric artery. Biochem. Biophys. Res. Commun. 177 (1991) 1127-1132
10. Jeyabalan A., Novak J., Danielson L.A., Kerchner L.J., Opett S.L., and Conrad K.P. Essential role for vascular gelatinase activity in relaxin-induced renal vasodilation, hyperfiltration, and reduced myogenic reactivity of small arteries. Circ. Res. 93 (2003) 1249-1257
11. Johnson R.J., Fink G.D., Watts S.W., and Galligan J.J. Endothelin receptor function in mesenteric veins from deoxycorticosterone acetate salt hypertensive rats. J. Hypertens. 20 (2002) 665-676
12. Ju H., Gros R., You X., Tsang S., Husain M., and Rabinovitch M. Conditional and targeted overexpression of vascular chymase causes hypertension in transgenic mice. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 7469-7474
13. Kido H., Nakano A., Okishima N., Wakabayashi H., Kishi F., Nakaya Y., Yoshizumi M., and Tamaki T. Human chymase, an enzyme forming novel bioactive 31-amino acid length endothelins. Biol. Chem. 379 (1998) 885-891
14. Kido T., Sawamura T., and Masaki T. The processing pathway of endothelin-1 production. J. Cardiovasc. Pharmacol. 31 S1 (1998) S13-S15
15. Kirimura K., Takai S., Jin D., Muramatsu M., Kishi K., Yoshikaw K., Nakabayashi M., Mino Y., and Miyazaki M. Role of chymase-dependent angiotensin II formation in regulating blood pressure in spontaneously hypertensive rats. Hypertens. Res. 28 (2005) 457-464
16. Li M., Liu K., Michalicek J., Angus J.A., Hunt J.E., Dell'Italia L.J., Feneley M.P., Graham R.M., and Husain A. Involvement of chymase-mediated angiotensin II generation in blood pressure regulation. J. Clin. Invest. 114 (2004) 112-120
17. Maguire J., and Davenport A.P. Alternative pathway to endothelin-converting enzyme for the synthesis of endothelin in human blood vessels. J. Cardiovasc. Pharmacol. 44 S1 (2004) S27-S29
18. Maguire J.J., Johnson C.M., Mockridge J.W., et al. Endothelin converting enzyme (ECE) activity in human vascular smooth muscle. Br. J. Pharmacol. 122 (1997) 1647-1654
19. Maguire J.J., Kuc R.E., and Davenport A.P. Vasoconstrictor activity of novel endothelin peptide, ET-1(1-31), in human mammary and coronary arteries in vitro. Br. J. Pharmacol. 134 (2001) 1360-1366
20. Matsumura Y., Ikegawa R., Tsukahara Y., Takaoka M., and Morimoto S. Conversion of big endothelin-1 to endothelin-1 by two types of metalloproteinases of cultured porcine vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 178 (1991) 899-905
21. A receptor selective agonist, stimulates proliferation of cultured rat zona glomerulosa cells. FEBS Lett. 487 (2000) 194-198
22. McMahon E.G., Palomo M.A., Brown MA., Bertenshaw S.R., and Carter J.S. Effect of phosphoramidon (endothelin converting enzyme inhibitor) and BQ-123 (endothelin receptor subtype A antagonist) on blood pressure in hypertensive rats. Am. J. Hypertens. 6 (1993) 667-673
23. Merchant S.J., and Davidge S.T. The role of matrix metalloproteinases in vascular function: implications for normal pregnancy and preeclampsia. BJOG 111 (2004) 931-939
24. Nagase H., Visse R., and Murphy G. Structure and function of matrix metalloproteinases and TIMPS. Cardiovasc. Res. 69 (2006) 562-573
25. Nagata N., Niwa Y., and Nakaya T. A novel 31-amino acid length endothelin, ET-1(1-31), can act as a biologically active peptide for vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 275 (2000) 595-600
26. Pinney S.P., Chen H.J., Liang D., Wang X., Schwartz A., and Rabbani L.E. Minocycline inhibits smooth muscle cell proliferation, migration and neointima formation after arterial injury. J. Cardiovasc. Pharmacol. 42 (2003) 469-476
27. Quaschning T. Vasopeptidase inhibition for blood pressure control: emerging experience. Curr. Pharm. Des. 11 (2005) 3293-3299
28. Roques B.P. Cell surface metallopeptidases involved in blood pressure regulation: structure, inhibition and clinical perspectives. Pathol. Biol. 46 (1998) 191-200
29. Schiffrin E.L. Role of endothelin-1 in hypertension and vascular disease. Am. J. Hypertens. 14 (2001) 83S-89S
30. Schweizer A., Valdenaire O., Nelbock P., Deuschle U., Dumas Milne Edwarrds J.B., Stumpf J.G., and Loffler B.M. Human endothelin-converting enzyme (ECE-1): three isoforms with distinct subcellular localizations. Biochem. J. 328 (1997) 871-877
31. Struck J., Morgenthaler N.G., and Bergmann A. Proteolytic processing patterns of the endothelin-1 precursor in vivo. Peptides 26 (2005) 2482-2486
32. Thakali K., Fink G.D., and Watts S.W. Arteries and veins desensitize differently to endothelin-1. J. Cardiovasc. Pharmacol. 43 (2004) 387-393
33. Trapani A.J., De Lombaert S., Kuzmich S., and Jeng A.Y. Inhibition of big ET-1-induced pressor response by an orally active dual inhibitor of endothelin-converting enzyme and neutral endopeptidase 24.11. J. Cardiovasc. Pharmacol. 26 S3 (1995) S69-S71
34. Vemulapalli S., Watkins R.W., Brown A., Cook J., Bernardino V., and Chiu P.J. Disparate effects of phosphoramidon on blood pressure in SHR and DOCA-salt hypertensive rats. Life Sci. 53 (1993) 783-793
35. Wang H., Chen A.F., Watts S.W., Galligan J.J., and Fink G.D. Endothelin in the splanchnic vascular bed of DOCA-salt hypertensive rats. Am. J. Physiol, Heart Circ. Physiol. 288 (2005) H729-H736
36. Watts S.W., Fink G.D., Northcott C.A., and Galligan J.J. Endothelin-1-induced venous contraction is maintained in DOCA-salt hypertension; studies with receptor agonists. Br. J. Pharmacol. 137 (2002) 69-79
37. Wypij D.M., Nichols J.S., Novak P.J., Stacy D.L., Berman J., and Wiseman J.S. Role of mast cell chymase in the extracellular processing of big endothelin-1 to endothelin-1 in the perfused rat lung. Biochem. Pharmacol. 43 (1992) 845-853
38. Yanagisawa M., Kurihara H., Kimura S., Tomobe Y., Kobayashi M., Mitsui Y., Yazaki Y., Goto K., and Masaki T. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332 (1988) 411-415