Cellular distribution of the renal bumetanide-sensitive Na-K-2Cl cotransporter BSC-1 in the inner stripe of the outer medulla during the development of hypertension in the spontaneously hypertensive rat

Clinical and Experimental Pharmacology and Physiology

Volumn 34, Issue 12, 2007, Pages 1307-1312

  Sonalker, Prajakta A ^a   Tofovic, Stevan P ^a   Jackson, Edwin K ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Apical membrane; BSC 1; Intracellular vesicles; Kidney; mRNA; NKCC2; Protein trafficking; Reverse transcription polymerase chain reaction; Spontaneously hypertensive rat; Western blotting; Wistar Kyoto rat

Indexed keywords

BUMETANIDE; CHLORIDE; POTASSIUM; PROTEIN BSC 1; SODIUM; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISEASE COURSE; DRUG SENSITIVITY; HYPERTENSION; KIDNEY PARENCHYMA; MALE; MEAN ARTERIAL PRESSURE; MEDULLA OBLONGATA; NONHUMAN; PROTEIN EXPRESSION; PROTEIN TRANSPORT; RAT; STEADY STATE; WESTERN BLOTTING;

ANIMALS; BLOOD PRESSURE; CELL MEMBRANE; HYPERTENSION; KIDNEY MEDULLA; MALE; PROTEIN TRANSPORT; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RNA, MESSENGER; SODIUM-POTASSIUM-CHLORIDE SYMPORTERS;

EID: 35548987483     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2007.04747.x     Document Type: Article

References (33)

1. Roman RJ, Cowley Jr. AW. Abnormal pressure-diuresis-natriuresis response in spontaneously hypertensive rats. Am. J. Physiol. 1985 248 : F199 205.
2. Roman RJ. Altered pressure-natriuresis relationship in young spontaneously hypertensive rats. Hypertension 1987 9 (Suppl. III III 130 6.
3. Rettig R, Folberth CG, Graf C, Kopf D, Stauss H, Unger T. Post-transplantation hypertension in recipients of renal grafts from hypertensive donor rats. Clin. Invest. Med. 1991 14 : 492 8.
4. Rettig R, Folberth CG, Graf C, Kopf D, Stauss H, Unger T. Are renal mechanisms involved in primary hypertension? Evidence from kidney transplantation studies in rats. Klin. Wochenschr. 1991 69 : 597 602.
5. Sonalker PA, Tofovic SP, Jackson EK. Increased expression of the sodium transporter BSC-1 in spontaneously hypertensive rats. J. Pharmacol. Exp. Ther. 2004 311 : 1052 61.
6. Nielsen S, Maunsbach AB, Ecelbarger CA, Knepper MA. Ultrastructural localization of Na-K-2Cl cotransporter in thick ascending limb and macula densa of rat kidney. Am. J. Physiol. 1998 275 : F885 93.
7. Gimenez I, Forbush B. Short-term stimulation of the renal Na-K-Cl cotransporter (NKCC2) by vasopressin involves phosphorylation and membrane translocation of the protein. J. Biol. Chem. 2003 278 : 26 946 51.
8. Marples D, Knepper MA, Christensen EI, Nielsen S. Redistribution of aquaporin-2 water channels induced by vasopressin in rat kidney inner medullary collecting duct. Am. J. Physiol. 1995 269 : C655 64.
9. Ecelbarger CA, Terris J, Frindt G et al. Aquaporin-3 water channel localization and regulation in rat kidney. Am. J. Physiol. 1995 269 : F663 72.
10. Sonalker PA, Jackson EK. Norepineprhine, via β-adrenoceptors, regulates butmetanide-sensitive cotransporter type 1 expression in thick ascending limb cells. Hypertension 2007 49 : 1 7.
11. Rioux F, Berkowitz BA. Role of the thyroid gland in the development and maintenance of spontaneous hypertension in rats. Circ. Res. 1977 40 : 306 12.
12. + exchange activity and NHE-3 expression in renal tubules from the spontaneously hypertensive rat. Kidney Int. 2002 62 : 157 65.
13. Heckmann U, Zidek W, Schurek HJ. Sodium reabsorption in the isolated perfused kidney of normotensive and spontaneously hypertensive rats. J. Hypertens. Suppl. 1989 7 : S172 3.
14. Raine AE, Roberts AF, Ledingham JG. Resetting of pressure-natriuresis and frusemide sensitivity in spontaneously hypertensive rats. J. Hypertens. Suppl. 1984 2 : S359 61.
15. Gamba G. Molecular biology of distal nephron sodium transport mechanisms. Kidney Int. 1999 56 : 1606 22.
16. Wright FS, Schnermann J. Interference with feedback control of glomerular filtration rate by furosemide, triflocin, and cyanide. J. Clin. Invest. 1974 53 : 1695 708.
17. Calo L, Davis PA, Semplicini A. Control of vascular tone in the syndromes of Bartter and Gitelman. Crit. Rev. Clin. Lab. Sci. 2000 37 : 503 22.
18. Takahashi N, Chernavvsky DR, Gomez RA, Igarashi P, Gitelman HJ, Smithies O. Uncompensated polyuria in a mouse model of Bartter's syndrome. Proc. Natl Acad. Sci. USA 2000 97 : 5434 9.
19. Manning J, Beutler K, Knepper MA, Vehaskari VM. Upregulation of renal BSC1 and TSC in prenatally programmed hypertension. Am. J. Physiol. Renal Physiol. 2002 283 : F202 6.
20. + transporters in the early phase of genetic hypertension. Am. J. Physiol. Renal Physiol. 2005 288 : F1173 82.
21. Bianchi G, Fox U, Di Francesco GF, Giovanetti AM, Pagetti D. Blood pressure changes produced by kidney cross-transplantation between spontaneously hypertensive rats and normotensive rats. Clin. Sci. Mol. Med. 1974 47 : 435 48.
22. Bianchi G, Fox U, Imbasciati E. The development of a new strain of spontaneously hypertensive rats. Life Sci. 1974 14 : 339 47.
23. Becker RHA, Baldes L, Treudler M. Loop diuretics combined with an ACE inhibitor for treatment of hypertension: A study with furosemide, piretanide, and ramipril in spontaneously hypertensive rats. Cardiovasc. Pharmacol. 1989 13 (Suppl. 3 S35 9.
24. +-exchanger 3 activity and its gene in the spontaneously hypertensive rat kidney. J. Hypertens. 1997 15 : 43 8.
25. Sonalker PA, Zhang XC, Tofovic SP, Jackson EK. Regulation of the abundance of the renal bumetanide-sensitive Na-K-2Cl cotransporter BSC-1/NKCC2 and water channel aquaporin-2 by norepinephrine. FASEB J. 2005 19 : A112 (Abstract).
26. Stegbauer J, Vonend O, Oberhauser V, Sellin L, Rump LC. Angiotensin II receptor modulation of renal vascular resistance and neurotransmission in young and adult spontaneously hypertensive rats. Kidney Blood Pressure Res. 2005 28 : 20 6.
27. Wang T, Kobayashi Y, Nabika T, Takabatake T. Enhanced sympathetic control of renal function in rats congenic for the hypertension-related region on chromosome 1. Clin. Exp. Pharmacol. Physiol. 2005 32 : 1055 60.
28. DiBona GF, Jones SY, Sawin LL. Renal sympathetic neural mechanisms as intermediate phenotype in spontaneously hypertensive rats. Hypertension 1996 27 : 626 30.
29. DiBona GF, Jones SY. Analysis of renal sympathetic nerve responses to stress. Hypertension 1995 25 : 531 8.
30. Gattone VH 2nd, Evan AP, Overhage JM, Severs WB. Developing renal innervation in the spontaneously hypertensive rat: Evidence for a role of the sympathetic nervous system in renal damage. J. Hypertens. 1990 8 : 423 8.
31. Lundin S, Ricksten SE, Thoren P. Renal sympathetic activity in spontaneously hypertensive rats and normotensive controls, as studied by three different methods. Acta Physiol. Scand. 1984 120 : 265 72.
32. Winternitz SR, Oparil S. Importance of the renal nerves in the pathogenesis of experimental hypertension. Hypertension 1982 4 (Suppl. III III 108 14.
33. Jonassen TE, Brond L, Torp M et al. Effects of renal denervation on tubular sodium handling in rats with CBL-induced liver cirrhosis. Am. J. Physiol. Renal Physiol. 2003 284 : F555 63.