Can Critically Short Telomeres Cause Functional Exhaustion of Progenitor Cells in Postinfarction Heart Failure?

Journal of the American College of Cardiology

Volumn 50, Issue 19, 2007, Pages 1911-1912

  Oeseburg, Hisko ^a   Westenbrink, B Daan ^a   de Boer, Rudolf A ^a   van Gilst, Wiek H ^a   van Veldhuisen, Dirk J ^a   van der Harst, Pim ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELL STRESS; CONGESTIVE CARDIOMYOPATHY; HEART FAILURE; HEART INFARCTION; HUMAN; ISCHEMIC HEART DISEASE; LETTER; PRIORITY JOURNAL; STEM CELL; TELOMERE;

CARDIOMYOPATHY, DILATED; CELL AGING; HEART FAILURE; HUMANS; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; MYOCYTES, CARDIAC; RISK FACTORS; STEM CELLS; TELOMERE;

EID: 35548972941     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2007.07.055     Document Type: Letter

References (5)

1. Kissel C.K., Lehmann R., Assmus B., et al. Selective functional exhaustion of hematopoietic progenitor cells in the bone marrow of patients with postinfarction heart failure. J Am Coll Cardiol 49 (2007) 2341-2349
2. Blackburn E.H. Switching and signaling at the telomere. Cell 106 (2001) 661-673
3. Wong J.M., and Collins K. Telomere maintenance and disease. Lancet 362 (2003) 983-988
4. van der Harst P., van der Steege G., de Boer R.A., et al. Telomere length of circulating leukocytes is decreased in patients with chronic heart failure. J Am Coll Cardiol 49 (2007) 1459-1464
5. Spyridopoulos I., Haendeler J., Urbich C., et al. Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells. Circulation 110 (2004) 3136-3142