The UDP-glucuronosyltransferase 2B7 isozyme is responsible for gemfibrozil glucuronidation in the human liver

Drug Metabolism and Disposition

Volumn 35, Issue 11, 2007, Pages 2040-2044

  Mano, Yuji ^a   Usui, Takashi ^a   Kamimura, Hidetaka ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; FLURBIPROFEN; GEMFIBROZIL; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A3; GLUCURONOSYLTRANSFERASE 1A9; GLUCURONOSYLTRANSFERASE 2B7; MEFENAMIC ACID; PROTEIN UGT2B17; PROTEIN UGT2B4; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CATALYSIS; DRUG BINDING; DRUG METABOLISM; DRUG STRUCTURE; ENZYME ACTIVITY; GLUCURONIDATION; HUMAN; LIVER MICROSOME; PRIORITY JOURNAL;

ANTILIPEMIC AGENTS; CATALYSIS; ENZYME INHIBITORS; ESTRADIOL; FLURBIPROFEN; GEMFIBROZIL; GLUCURONOSYLTRANSFERASE; GLYCOSYLATION; HUMANS; ISOENZYMES; KINETICS; MEFENAMIC ACID; MICROSOMES, LIVER; MOLECULAR STRUCTURE; MORPHINE; PROPOFOL; RECOMBINANT PROTEINS;

EID: 35548965586     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.107.017269     Document Type: Article

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