Maggot debridement therapy in chronic wound care

Hong Kong Medical Journal

Volumn 13, Issue 5, 2007, Pages 382-386

  Chan, Dominic C W ^a   Fong, Daniel H F ^a   Leung, June Y Y ^a   Patil, N G ^a   Leung, Gilberto K K ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Debridement; Diptera; Larva; Wound healing; Wounds and injuries

Indexed keywords

AMMONIA; PROTEINASE;

ARTICLE; CHRONIC WOUND; COST EFFECTIVENESS ANALYSIS; DEBRIDEMENT; DECUBITUS; DIABETIC FOOT; ESCHERICHIA COLI; FLY; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; LARVA; LITERATURE; LUCILIA SERICATA; MAGGOT; MAGGOT THERAPY; MEDLINE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; WOUND CARE; WOUND HEALING;

ANIMALS; CHRONIC DISEASE; DEBRIDEMENT; DIABETIC FOOT; DIPTERA; HUMANS; LARVA; PRESSURE ULCER; VARICOSE ULCER; WOUND HEALING;

EID: 35548958300     PISSN: 10242708     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Attinger CE, Janis JE, Steinberg J, Schwartz J, Al-Attar A, Couch K. Clinical approach to wounds: debridement and wound bed preparation including the use of dressings and wound-healing adjuvants. Plast Reconstr Surg 2006;117(7 Suppl):72S-109S.
2. Collier M. The use of advanced biological and tissue-engineered wound products. Nurs Stand 2006;21:68,70,72 passim.
3. Thomas S, Jones M. Wound debridement: evaluating the costs. Nurs Stand 2001;15:59-61.
4. Wollina U, Liebold K, Schmidt WD, et al. Biosurgery supports granulation and debridement in chronic wounds - clinical data and remittance spectroscopy measurement. Int J Dermatol 2002;41:635-9.
5. Courtenay M, Church JC, Ryan TJ. Larva therapy in wound management. J R Soc Med 2000;93:72-4.
6. Wolff H, Hansson C. Larval therapy - an effective method of ulcer debridement. Clin Exp Dermatol 2003;28:134-7.
7. Richardson M. The benefits of larval therapy in wound care. Nurs Stand 2004;19:70,72,74 passim.
8. Paré A. The battell of S. Quintin (1557). In: Keynes G, editor. The Apologie and Treatise of Ambroise Paré. Chicago: The University of Chicago Press; 1952:68-70.
9. Goldstein HI. Maggots in the treatment of wound and bone infections. J Bone Joint Surg Am 1931;13:476-8.
10. Larrey D. Des vers ou larves de la mouche bleue. Clin Chir 1829;1:51.
11. Mumcuoglu KY. Clinical applications for maggots in wound care. Am J Clin Dermatol 2001;2:219-27.
12. Beasley WD, Hirst G. Making a meal of MRSA - the role of biosurgery in hospital-acquired infection. J Hosp Infect 2004;56:6-9.
13. Wollina U, Karte K, Herold C, Looks A. Biosurgery in wound healing - the renaissance of maggot therapy. J Eur Acad Dermatol Venereol 2000;14:285-9.
14. Barnard DR. Skeletal-muscular mechanisms of the larva of Lucilia sericata (Meigen) in relation to feeding habit. Pan-Pac Entomol 1977;53:223-9.
15. Chambers L, Woodrow S, Brown AP, et al. Degradation of extracellular matrix components by defined proteinases from the greenbottle larva Lucilia sericata used for the clinical debridement of non-healing wounds. Br J Dermatol 2003;148:14-23.
16. Bexfield A, Nigam Y, Thomas S, Ratcliffe NA. Detection and partial characterisation of two antibacterial factors from the excretions/secretions of the medicinal maggot Lucilia sericata and their activity against methicillinresistant Staphylococcus aureus (MRSA). Microbes Infect 2004;6:1297-304.
17. Robinson W. Ammonium bicarbonate secreted by surgical maggots stimulates healing in purulent wounds. Am J Surg 1940;(47):111-5.
18. Mumcuoglu KY, Miller J, Mumcuoglu M, Friger M, Tarshis M. Destruction of bacteria in the digestive tract of the maggot of Lucilia sericata (Diptera: Calliphoridae). J Med Entomol 2001;38:161-6.
19. Prete PE. Growth effects of Phaenicia sericata larval extracts on fibroblasts: mechanism for wound healing by maggot therapy. Life Sci 1997;60:505-10.
20. Horobin AJ, Shakesheff KM, Pritchard DI. Maggots and wound healing: an investigation of the effects of secretions from Lucilia sericata larvae upon the migration of human dermal fibroblasts over a fibronectin-coated surface. Wound Repair Regen 2005;13:422-33.
21. Horobin AJ, Shakesheff KM, Pritchard DI. Promotion of human dermal fibroblast migration, matrix remodelling and modification of fibroblast morphology within a novel 3D model by Lucilia sericata larval secretions. J Invest Dermatol 2006;126:1410-8.
22. Smith AG, Powis RA, Pritchard DI, Britland ST. Greenbottle (Lucilia sericata) larval secretions delivered from a prototype hydrogel wound dressing accelerate the closure of model wounds. Biotechnol Prog 2006;22:1690-6.
23. Wayman J, Nirojogi V, Walker A, Sowinski A, Walker MA. The cost effectiveness of larval therapy in venous ulcers. J Tissue Viability 2000;10:91-4. Erratum in: J Tissue Viability 2001;11:51.
24. Sherman RA. Maggot versus conservative debridement therapy for the treatment of pressure ulcers. Wound Repair Regen 2002;10:208-14.
25. Sherman RA. Maggot therapy for treating diabetic foot ulcers unresponsive to conventional therapy. Diabetes Care 2003;26:446-51.
26. Armstrong DG, Salas P, Short B, et al. Maggot therapy in "lower-extremity hospice" wound care: fewer amputations and more antibiotic-free days. J Am Podiatr Med Assoc 2005;95:254-7.
27. Tanyuksel M, Araz E, Dundar K, et al. Maggot debridement therapy in the treatment of chronic wounds in a military hospital setup in Turkey. Dermatology 2005;210:115-8.
28. Sherman RA, Shimoda KJ. Presurgical maggot debridement of soft tissue wounds is associated with decreased rates of postoperative infection. Clin Infect Dis 2004;39:1067-70.
29. Husain ZS, Fallat LM. Maggot therapy for wound debridement in a traumatic foot-degloving injury: a case report. J Foot Ankle Surg 2003;42:371-6.
30. Steenvoorde P, Oskam J. Use of larval therapy to combat infection after breast-conserving surgery. J Wound Care 2005;14:212-3.
31. Dunn C, Raghavan U, Pfleiderer AG. The use of maggots in head and neck necrotizing fasciitis. J Laryngol Otol 2002;116:70-2.
32. Preuss SF, Stenzel MJ, Esriti A. The successful use of maggots in necrotizing fasciitis of the neck: a case report. Head Neck 2004;26:747-50.
33. Rozeboom AL, Steenvoorde P, Hartgrink HH, Jukema GN. Necrotising fasciitis of the leg following a simple pelvic fracture: case report and literature review. J Wound Care 2006;15:117-20.
34. Baer WS. The treatment of chronic osteomyelitis with the maggot (larva of the blow ßy). J Bone Joint Surg Am 1931;13:438-75.
35. Wang J, Wang S, Zhao G, Wang Z, Lineaweaver WC, Zhang F. Treatment of infected wounds with maggot therapy after replantation. J Reconstr Microsurg 2006;22:277-80.
36. Wollina U, Kinscher M, Fengler H. Maggot therapy in the treatment of wounds of exposed knee prostheses. Int J Dermatol 2005;44:884-6.
37. Sealby N. The use of maggot therapy in the treatment of a malignant foot wound. Br J Community Nurs 2004;9:S16-9.
38. Namias N, Varela JE, Varas RP, Quintana O, Ward CG. Biodebridement: a case report of maggot therapy for limb salvage after fourth-degree burns. J Burn Care Rehabil 2000;21:254-7.
39. Horn KL, Cobb AH Jr, Gates GA. Maggot therapy for subacute mastoiditis. Arch Otolaryngol 1976;102:377-9.
40. Tse TW. Maggot therapy in Hong Kong: a case report. Hong Kong J Dermatol Venereol 2006;14:78-81.
41. Drisdelle R. Maggot debridement therapy: a living cure. Nursing 2003;33:17.
42. Nuesch R, Rahm G, Rudin W, et al. Clustering of bloodstream infections during maggot debridement therapy using contaminated larvae of Protophormia terraenovae. Infection 2002;30:306-9.