Human Stem Cells for Heart Failure Treatment. Ready for Prime Time?**Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology.

Journal of the American College of Cardiology

Volumn 50, Issue 19, 2007, Pages 1894-1895

  Condorelli, Gianluigi ^a,b   Catalucci, Daniele ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b IRCCS MULTIMEDICA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MARROW CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL TRANSPLANTATION; EDITORIAL; EMBRYONIC STEM CELL; EXCITATION CONTRACTION COUPLING; GAP JUNCTION; HEART FAILURE; HEART FUNCTION; HEART MUSCLE CELL; HEMATOPOIETIC STEM CELL; HUMAN; MESENCHYME CELL; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION;

ANIMALS; CELL DIFFERENTIATION; CELL DIVISION; CELL SURVIVAL; EMBRYONIC STEM CELLS; HEART FAILURE; HEMODYNAMICS; HUMANS; MALE; MYOCARDIAL CONTRACTION; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; RATS; RATS, SPRAGUE-DAWLEY;

EID: 35548949334     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2007.07.057     Document Type: Editorial

References (19)

1. Orlic D., Kajstura J., Chimenti S., et al. Bone marrow cells regenerate infarcted myocardium. Nature 410 (2001) 701-705
2. Jiang Y., Jahagirdar B.N., Reinhardt R.L., et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 418 (2002) 41-49
3. Chien K.R. Stem cells: lost in translation. Nature 428 (2004) 607-608
4. Rosenzweig A. Cardiac cell therapy-mixed results from mixed cells. N Engl J Med 355 (2006) 1274-1277
5. Harada M., Qin Y., Takano H., et al. G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes. Nat Med 11 (2005) 305-311
6. Fazel S., Cimini M., Chen L., et al. Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines. J Clin Invest 116 (2006) 1865-1877
7. Gallo P., Peschle C., and Condorelli G. Sources of cardiomyocytes for stem cell therapy: an update. Pediatr Res 59 (2006) 79R-83R
8. Guan K., Nayernia K., Maier L.S., et al. Pluripotency of spermatogonial stem cells from adult mouse testis. Nature 440 (2006) 1199-1203
9. Magnuson T., Epstein C.J., Silver L.M., and Martin G.R. Pluripotent embryonic stem cell lines can be derived from tw5/tw5 blastocysts. Nature 298 (1982) 750-753
10. Jaenisch R. Human cloning-the science and ethics of nuclear transplantation. N Engl J Med 351 (2004) 2787-2791
11. Wobus A.M., Wallukat G., and Hescheler J. Pluripotent mouse embryonic stem cells are able to differentiate into cardiomyocytes expressing chronotropic responses to adrenergic and cholinergic agents and Ca2+ channel blockers. Differentiation 48 (1991) 173-182
12. Soonpaa M.H., Koh G.Y., Klug M.G., and Field L.J. Formation of nascent intercalated disks between grafted fetal cardiomyocytes and host myocardium. Science 264 (1994) 98-101
13. Menard C., Hagege A.A., Agbulut O., et al. Transplantation of cardiac-committed mouse embryonic stem cells to infarcted sheep myocardium: a preclinical study. Lancet 366 (2005) 1005-1012
14. Thomson J.A., Itskovitz-Eldor J., Shapiro S.S., et al. Embryonic stem cell lines derived from human blastocysts. Science 282 (1998) 1145-1147
15. Kehat I., Kenyagin-Karsenti D., Snir M., et al. Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. J Clin Invest 108 (2001) 407-414
16. Kehat I., Khimovich L., Caspi O., et al. Electromechanical integration of cardiomyocytes derived from human embryonic stem cells. Nat Biotechnol 22 (2004) 1282-1289
17. Caspi O., Huber I., Kehat I., et al. Transplantation of human embryonic stem cell-derived cardiomyocytes improves myocardial performance in infarcted rat hearts. J Am Coll Cardiol 50 (2007) 1884-1893
18. Minami E., Reinecke H., and Murry C.E. Skeletal muscle meets cardiac muscle. Friends or foes?. J Am Coll Cardiol 41 (2003) 1084-1086
19. Drukker M., Katchman H., Katz G., et al. Human embryonic stem cells and their differentiated derivatives are less susceptible to immune rejection than adult cells. Stem Cells 24 (2006) 221-229