-
1
-
-
0025010979
-
The GTPase superfamily: A conserved switch for diverse cell functions
-
Bourne HR, Sanders DA, McCormick F. The GTPase superfamily: a conserved switch for diverse cell functions. Nature 348:125-132, 1990.
-
(1990)
Nature
, vol.348
, pp. 125-132
-
-
Bourne, H.R.1
Sanders, D.A.2
McCormick, F.3
-
2
-
-
0025078512
-
The cellular functions of small GTP-binding proteins
-
Hall A. The cellular functions of small GTP-binding proteins. Science 249:635-640, 1990.
-
(1990)
Science
, vol.249
, pp. 635-640
-
-
Hall, A.1
-
4
-
-
0027289305
-
Rab17, a novel small GTPase, is specific for epithelial cells and is induced during cell polarization
-
Lutcke A, Jansson S, Parton RG, Chavrier P, Valencia A, Huber LA, Lehtonen E, Zerial M. Rab17, a novel small GTPase, is specific for epithelial cells and is induced during cell polarization. J Cell Biol 121:553-564, 1993.
-
(1993)
J Cell Biol
, vol.121
, pp. 553-564
-
-
Lutcke, A.1
Jansson, S.2
Parton, R.G.3
Chavrier, P.4
Valencia, A.5
Huber, L.A.6
Lehtonen, E.7
Zerial, M.8
-
5
-
-
0032498797
-
Rab17 regulates membrane trafficking through apical recycling endosomes in polarized epithelial cells
-
Zacchi P, Stenmark H, Parton RG, Orioli D, Lim F, Giner A, Mellman I, Zerial M, Murphy C. Rab17 regulates membrane trafficking through apical recycling endosomes in polarized epithelial cells. J Cell Biol 140:1039-1053, 1998.
-
(1998)
J Cell Biol
, vol.140
, pp. 1039-1053
-
-
Zacchi, P.1
Stenmark, H.2
Parton, R.G.3
Orioli, D.4
Lim, F.5
Giner, A.6
Mellman, I.7
Zerial, M.8
Murphy, C.9
-
6
-
-
33845313646
-
-
Heo WD, Inoue T, Park WS, Kim ML, Park BO, Wandless TJ, Meyer T. PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane. Science 314:1458-1461, 2006.
-
Heo WD, Inoue T, Park WS, Kim ML, Park BO, Wandless TJ, Meyer T. PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane. Science 314:1458-1461, 2006.
-
-
-
-
7
-
-
33645222317
-
Direct interaction with Rab11a targets the epithelial Ca2+ channels TRPV5 and TRPV6 to the plasma membrane
-
van de Graaf SF, Chang Q, Mensenkamp AR, Hoenderop JG, Bindels RJ. Direct interaction with Rab11a targets the epithelial Ca2+ channels TRPV5 and TRPV6 to the plasma membrane. Mol Cell Biol 26:303-312, 2006.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 303-312
-
-
van de Graaf, S.F.1
Chang, Q.2
Mensenkamp, A.R.3
Hoenderop, J.G.4
Bindels, R.J.5
-
8
-
-
33747721427
-
Analysis of the complex between Ca2+ channel beta-subunit and the Rem GTPase
-
Finlin BS, Correll RN, Pang C, Crump SM, Satin J, Andres DA. Analysis of the complex between Ca2+ channel beta-subunit and the Rem GTPase. J Biol Chem 281:23557-23566, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 23557-23566
-
-
Finlin, B.S.1
Correll, R.N.2
Pang, C.3
Crump, S.M.4
Satin, J.5
Andres, D.A.6
-
9
-
-
0032511197
-
The Small GTP-binding protein RhoA regulates a delayed rectifier potassium channel
-
Cachero TG, Morielli AD, Peralta EG. The Small GTP-binding protein RhoA regulates a delayed rectifier potassium channel. Cell 93:1077-1085, 1998.
-
(1998)
Cell
, vol.93
, pp. 1077-1085
-
-
Cachero, T.G.1
Morielli, A.D.2
Peralta, E.G.3
-
10
-
-
33748746597
-
Rapid translocation and insertion of the epithelial Na+ channel in response to RhoA signaling
-
Pochynyuk O, Medina J, Gamper N, Genth H, Stockand JD, Staruschenko A. Rapid translocation and insertion of the epithelial Na+ channel in response to RhoA signaling. J Biol Chem 281:26520-26527, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 26520-26527
-
-
Pochynyuk, O.1
Medina, J.2
Gamper, N.3
Genth, H.4
Stockand, J.D.5
Staruschenko, A.6
-
11
-
-
34247343727
-
Regulation of epithelial sodium channels (ENaC) by small G-proteins
-
Pochynyuk OM, Zheleznova NN, Medina JL, Stockand JD, Staruschenko AV. Regulation of epithelial sodium channels (ENaC) by small G-proteins. Biol Membr 23:382-393, 2006.
-
(2006)
Biol Membr
, vol.23
, pp. 382-393
-
-
Pochynyuk, O.M.1
Zheleznova, N.N.2
Medina, J.L.3
Stockand, J.D.4
Staruschenko, A.V.5
-
12
-
-
4143054903
-
Rapid vesicular translocation and insertion of TRP channels
-
Bezzerides VJ, Ramsey IS, Kotecha S, Greka A, Clapham DE. Rapid vesicular translocation and insertion of TRP channels. Nat Cell Biol 6:709-720, 2004.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 709-720
-
-
Bezzerides, V.J.1
Ramsey, I.S.2
Kotecha, S.3
Greka, A.4
Clapham, D.E.5
-
13
-
-
0026679892
-
Raf functions downstream of Ras1 in the Sevenless signal transduction pathway
-
Dickson B, Sprenger F, Morrison D, Hafen E. Raf functions downstream of Ras1 in the Sevenless signal transduction pathway. Nature 360:600-603, 1992.
-
(1992)
Nature
, vol.360
, pp. 600-603
-
-
Dickson, B.1
Sprenger, F.2
Morrison, D.3
Hafen, E.4
-
14
-
-
0036735940
-
Activation of mitogen-activated protein kinase (mitogen-activated protein kinase/extracellular signal-regulated kinase) cascade by aldosterone
-
Hendron E, Stockand JD. Activation of mitogen-activated protein kinase (mitogen-activated protein kinase/extracellular signal-regulated kinase) cascade by aldosterone. Mol Biol Cell 13:3042-3054, 2002.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 3042-3054
-
-
Hendron, E.1
Stockand, J.D.2
-
15
-
-
0027370827
-
Reconstitution of the Raf-1-MEK-ERK signal transduction pathway in vitro
-
Macdonald SG, Crews CM, Wu L, Driller J, Clark R, Erikson RL, McCormick F. Reconstitution of the Raf-1-MEK-ERK signal transduction pathway in vitro. Mol Cell Biol 13:6615-6620, 1993.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 6615-6620
-
-
Macdonald, S.G.1
Crews, C.M.2
Wu, L.3
Driller, J.4
Clark, R.5
Erikson, R.L.6
McCormick, F.7
-
16
-
-
0037230196
-
Aldosterone stimulates proliferation of cardiac fibroblasts by activating Ki-RasA and MAPK1/2 signaling
-
Stockand JD, Meszaros JG. Aldosterone stimulates proliferation of cardiac fibroblasts by activating Ki-RasA and MAPK1/2 signaling. Am J Physiol Heart Circ Physiol 284:H176-H184, 2003.
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.284
-
-
Stockand, J.D.1
Meszaros, J.G.2
-
17
-
-
33745307617
-
-
Shaw RJ, Cantley LC. Ras, PI(3)K and mTOR signalling controls tumour cell growth. Nature 441:424-430, 2006.
-
Shaw RJ, Cantley LC. Ras, PI(3)K and mTOR signalling controls tumour cell growth. Nature 441:424-430, 2006.
-
-
-
-
19
-
-
0028153277
-
Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator
-
Hofer F, Fields S, Schneider C, Martin GS. Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator. Proc Natl Acad Sci U S A 91:11089-11093, 1994.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 11089-11093
-
-
Hofer, F.1
Fields, S.2
Schneider, C.3
Martin, G.S.4
-
21
-
-
33746859372
-
Cyclic AMP-dependent and Epac-mediated activation of R-Ras by G protein-coupled receptors leads to phospholipase D stimulation
-
Lopez De JM, Stope MB, Oude Weernink PA, Mahlke Y, Borgermann C, Ananaba VN, Rimmbach C, Rosskopf D, Michel MC, Jakobs KH, Schmidt M. Cyclic AMP-dependent and Epac-mediated activation of R-Ras by G protein-coupled receptors leads to phospholipase D stimulation. J Biol Chem 281:21837-21847, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 21837-21847
-
-
Lopez, D.J.1
Stope, M.B.2
Oude Weernink, P.A.3
Mahlke, Y.4
Borgermann, C.5
Ananaba, V.N.6
Rimmbach, C.7
Rosskopf, D.8
Michel, M.C.9
Jakobs, K.H.10
Schmidt, M.11
-
22
-
-
0027432825
-
Lysophosphatidic acid stimulates mitogen-activated protein kinase activation via a G-protein-coupled pathway requiring p21ras and p74raf-1
-
Howe LR, Marshall CJ. Lysophosphatidic acid stimulates mitogen-activated protein kinase activation via a G-protein-coupled pathway requiring p21ras and p74raf-1. J Biol Chem 268:20717-20720, 1993.
-
(1993)
J Biol Chem
, vol.268
, pp. 20717-20720
-
-
Howe, L.R.1
Marshall, C.J.2
-
23
-
-
0028982948
-
Distinct pathways of Gi- and Gq-mediated mitogen-activated protein kinase activation
-
Hawes BE, van BT, Koch WJ, Luttrell LM, Lefkowitz RJ. Distinct pathways of Gi- and Gq-mediated mitogen-activated protein kinase activation. J Biol Chem 270:17148-17153, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 17148-17153
-
-
Hawes, B.V.B.1
Koch, W.J.2
Luttrell, L.M.3
Lefkowitz, R.J.4
-
24
-
-
4444264303
-
Ras activates the epithelial Na(+) channel through phosphoinositide 3-OH kinase signaling
-
Staruschenko A, Patel P, Tong Q, Medina JL, Stockand JD. Ras activates the epithelial Na(+) channel through phosphoinositide 3-OH kinase signaling. J Biol Chem 279:37771-37778, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 37771-37778
-
-
Staruschenko, A.1
Patel, P.2
Tong, Q.3
Medina, J.L.4
Stockand, J.D.5
-
25
-
-
18944373042
-
Ras couples phosphoinositide 3-OH kinase to the epithelial Na+ channel
-
Staruschenko A, Pochynyuk OM, Tong Q, Stockand JD. Ras couples phosphoinositide 3-OH kinase to the epithelial Na+ channel. Biochim Biophys Acta 1669:108-115, 2005.
-
(2005)
Biochim Biophys Acta
, vol.1669
, pp. 108-115
-
-
Staruschenko, A.1
Pochynyuk, O.M.2
Tong, Q.3
Stockand, J.D.4
-
26
-
-
0033544885
-
Regulation of Na+ reabsorption by the aldosterone-induced small G protein K-Ras2A
-
Stockand JD, Spier BJ, Worrell RT, Yue G, Al-Baldawi N, Eaton DC. Regulation of Na+ reabsorption by the aldosterone-induced small G protein K-Ras2A. J Biol Chem 274:35449-35454, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 35449-35454
-
-
Stockand, J.D.1
Spier, B.J.2
Worrell, R.T.3
Yue, G.4
Al-Baldawi, N.5
Eaton, D.C.6
-
27
-
-
0031741185
-
Ras pathway activates epithelial Na+ channel and decreases its surface expression in Xenopus oocytes
-
Mastroberardino L, Spindler B, Forster I, Loffing J, Assandri R, May A, Verrey F. Ras pathway activates epithelial Na+ channel and decreases its surface expression in Xenopus oocytes. Mol Biol Cell 9:3417-3427, 1998.
-
(1998)
Mol Biol Cell
, vol.9
, pp. 3417-3427
-
-
Mastroberardino, L.1
Spindler, B.2
Forster, I.3
Loffing, J.4
Assandri, R.5
May, A.6
Verrey, F.7
-
28
-
-
0030972111
-
Characterization of early aldosterone-induced RNAs identified in A6 kidney epithelia
-
Spindler B, Mastroberardino L, Custer M, Verrey F. Characterization of early aldosterone-induced RNAs identified in A6 kidney epithelia. Pflugers Arch Eur J Physiol 434:323-331, 1997.
-
(1997)
Pflugers Arch Eur J Physiol
, vol.434
, pp. 323-331
-
-
Spindler, B.1
Mastroberardino, L.2
Custer, M.3
Verrey, F.4
-
29
-
-
0033047937
-
Aldosterone action: Induction of p21ras and fra-2 and transcription-independent decrease in myc, jun, and fos
-
Spindler B, Verrey F. Aldosterone action: induction of p21ras and fra-2 and transcription-independent decrease in myc, jun, and fos. Am J Physiol Cell Physiol 276:C1154-C1161, 1999.
-
(1999)
Am J Physiol Cell Physiol
, vol.276
-
-
Spindler, B.1
Verrey, F.2
-
30
-
-
0033858350
-
Structure and regulation of amiloride-sensitive sodium channels
-
Alvarez de la Rosa D, Canessa CM, Fyfe GK, Zhang P. Structure and regulation of amiloride-sensitive sodium channels. Annu Rev Physiol 62:573-594, 2000.
-
(2000)
Annu Rev Physiol
, vol.62
, pp. 573-594
-
-
Alvarez de la Rosa, D.1
Canessa, C.M.2
Fyfe, G.K.3
Zhang, P.4
-
31
-
-
4644268448
-
The epithelial sodium channel: From molecule to disease
-
Schild L. The epithelial sodium channel: from molecule to disease. Rev Physiol Biochem Pharmacol 151:93-107, 2004.
-
(2004)
Rev Physiol Biochem Pharmacol
, vol.151
, pp. 93-107
-
-
Schild, L.1
-
32
-
-
27844476338
-
Regulation of epithelial Na+ channel trafficking
-
Snyder PM. Regulation of epithelial Na+ channel trafficking. Endocrinology 146:5079-5085, 2005.
-
(2005)
Endocrinology
, vol.146
, pp. 5079-5085
-
-
Snyder, P.M.1
-
33
-
-
0036083469
-
New ideas about aldosterone signaling in epithelia
-
Stockand JD. New ideas about aldosterone signaling in epithelia. Am J Physiol Renal Physiol 282:F559-F576, 2002.
-
(2002)
Am J Physiol Renal Physiol
, vol.282
-
-
Stockand, J.D.1
-
34
-
-
0037023729
-
Modulation of the inward rectifier potassium channel IRK1 by the Ras signaling pathway
-
Giovannardi S, Forlani G, Balestrini M, Bossi E, Tonini R, Sturani E, Peres A, Zippel R. Modulation of the inward rectifier potassium channel IRK1 by the Ras signaling pathway. J Biol Chem 277:12158-12163, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 12158-12163
-
-
Giovannardi, S.1
Forlani, G.2
Balestrini, M.3
Bossi, E.4
Tonini, R.5
Sturani, E.6
Peres, A.7
Zippel, R.8
-
35
-
-
0026562003
-
p21ras oncogene protein selectively increases low-voltage-activated Ca2+ current density in embryonic chick dorsal root ganglion neurons
-
Hahnel C, Gottmann K, Wittinghofer A, Lux HD. p21ras oncogene protein selectively increases low-voltage-activated Ca2+ current density in embryonic chick dorsal root ganglion neurons. Eur J Neurosci 4:361-368, 1992.
-
(1992)
Eur J Neurosci
, vol.4
, pp. 361-368
-
-
Hahnel, C.1
Gottmann, K.2
Wittinghofer, A.3
Lux, H.D.4
-
36
-
-
0035821585
-
Regulation of Ca2+ channel expression at the cell surface by the small G-protein kir/Gem
-
Beguin P, Nagashima K, Gonoi T, Shibasaki T, Takahashi K, Kashima Y, Ozaki N, Geering K, Iwanaga T, Seino S. Regulation of Ca2+ channel expression at the cell surface by the small G-protein kir/Gem. Nature 411:701-706, 2001.
-
(2001)
Nature
, vol.411
, pp. 701-706
-
-
Beguin, P.1
Nagashima, K.2
Gonoi, T.3
Shibasaki, T.4
Takahashi, K.5
Kashima, Y.6
Ozaki, N.7
Geering, K.8
Iwanaga, T.9
Seino, S.10
-
37
-
-
0345060805
-
Regulation of voltage-gated calcium channel activity by the Rem and Rad GTPases
-
Finlin BS, Crump SM, Satin J, Andres DA. Regulation of voltage-gated calcium channel activity by the Rem and Rad GTPases. Proc Natl Acad Sci U S A 100:14469-14474, 2003.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 14469-14474
-
-
Finlin, B.S.1
Crump, S.M.2
Satin, J.3
Andres, D.A.4
-
38
-
-
0346725954
-
Phosphorylation of critical serine residues in gem separates cytoskeletal reorganization from down-regulation of calcium channel activity
-
Ward Y, Spinelli B, Quon MJ, Chen H, Ikeda SR, Kelly K. Phosphorylation of critical serine residues in gem separates cytoskeletal reorganization from down-regulation of calcium channel activity. Mol Cell Biol 24:651-661, 2004.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 651-661
-
-
Ward, Y.1
Spinelli, B.2
Quon, M.J.3
Chen, H.4
Ikeda, S.R.5
Kelly, K.6
-
39
-
-
27144558611
-
Expression of Rem2, an RGK family small GTPase, reduces N-type calcium current without affecting channel surface density
-
Chen H, Puhl HL, III, Niu SL, Mitchell DC, Ikeda SR. Expression of Rem2, an RGK family small GTPase, reduces N-type calcium current without affecting channel surface density. J Neurosci 25:9762-9772, 2005.
-
(2005)
J Neurosci
, vol.25
, pp. 9762-9772
-
-
Chen, H.1
Puhl III, H.L.2
Niu, S.L.3
Mitchell, D.C.4
Ikeda, S.R.5
-
40
-
-
0025324939
-
ras p21 and GAP inhibit coupling of muscarinic receptors to atrial K+ channels
-
Yatani A, Okabe K, Polakis P, Halenbeck R, McCormick F, Brown AM. ras p21 and GAP inhibit coupling of muscarinic receptors to atrial K+ channels. Cell 61:769-776, 1990.
-
(1990)
Cell
, vol.61
, pp. 769-776
-
-
Yatani, A.1
Okabe, K.2
Polakis, P.3
Halenbeck, R.4
McCormick, F.5
Brown, A.M.6
-
41
-
-
0025721155
-
Rap1A antagonizes the ability of Ras and Ras-Gap to inhibit muscarinic K+ channels
-
Yatani A, Quilliam LA, Brown AM, Bokoch GM. Rap1A antagonizes the ability of Ras and Ras-Gap to inhibit muscarinic K+ channels. J Biol Chem 266:22222-22226, 1991.
-
(1991)
J Biol Chem
, vol.266
, pp. 22222-22226
-
-
Yatani, A.1
Quilliam, L.A.2
Brown, A.M.3
Bokoch, G.M.4
-
42
-
-
4143073671
-
Effects of ras and Rap1 on electrical excitability of differentiated NG108-15 cells
-
Imamura Y, Matsumoto N, Kondo S, Kitayama H, Noda M. Effects of ras and Rap1 on electrical excitability of differentiated NG108-15 cells. Neuroscience 127:973-981, 2004.
-
(2004)
Neuroscience
, vol.127
, pp. 973-981
-
-
Imamura, Y.1
Matsumoto, N.2
Kondo, S.3
Kitayama, H.4
Noda, M.5
-
43
-
-
0042244245
-
Possible involvement of Rap1 and Ras in glutamatergic synaptic transmission
-
Imamura Y, Matsumoto N, Kondo S, Kitayama H, Noda M. Possible involvement of Rap1 and Ras in glutamatergic synaptic transmission. Neuroreport 14:1203-1207, 2003.
-
(2003)
Neuroreport
, vol.14
, pp. 1203-1207
-
-
Imamura, Y.1
Matsumoto, N.2
Kondo, S.3
Kitayama, H.4
Noda, M.5
-
44
-
-
0037162696
-
Ras and Rap control AMPA receptor trafficking during synaptic plasticity
-
Zhu JJ, Qin Y, Zhao M, Van AL, Malinow R. Ras and Rap control AMPA receptor trafficking during synaptic plasticity. Cell 110:443-455, 2002.
-
(2002)
Cell
, vol.110
, pp. 443-455
-
-
Zhu, J.J.1
Qin, Y.2
Zhao, M.3
Van, A.L.4
Malinow, R.5
-
45
-
-
0034213327
-
Rho GTPases and their effector proteins
-
Bishop AL, Hall A. Rho GTPases and their effector proteins. Biochem J 348:241-255, 2000.
-
(2000)
Biochem J
, vol.348
, pp. 241-255
-
-
Bishop, A.L.1
Hall, A.2
-
46
-
-
33645508702
-
Rac GTPase signaling through the PP5 protein phosphatase
-
Gentile S, Darden T, Erxleben C, Romeo C, Russo A, Martin N, Rossie S, Armstrong DL. Rac GTPase signaling through the PP5 protein phosphatase. Proc Natl Acad Sci U S A 103:5202-5206, 2006.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 5202-5206
-
-
Gentile, S.1
Darden, T.2
Erxleben, C.3
Romeo, C.4
Russo, A.5
Martin, N.6
Rossie, S.7
Armstrong, D.L.8
-
47
-
-
9644307893
-
Rho small GTPases activate the epithelial Na(+) channel
-
Staruschenko A, Nichols A, Medina JL, Camacho P, Zheleznova NN, Stockand JD. Rho small GTPases activate the epithelial Na(+) channel. J Biol Chem 279:49989-49994, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 49989-49994
-
-
Staruschenko, A.1
Nichols, A.2
Medina, J.L.3
Camacho, P.4
Zheleznova, N.N.5
Stockand, J.D.6
-
48
-
-
0036765586
-
Inhibitory effect of fluvastatin on lysophosphatidylcholine- induced nonselective cation current in guinea pig ventricular myocytes
-
Li L, Matsuoka I, Suzuki Y, Watanabe Y, Ishibashi T, Yokoyama K, Maruyama Y, Kimura J. Inhibitory effect of fluvastatin on lysophosphatidylcholine- induced nonselective cation current in guinea pig ventricular myocytes. Mol Pharmacol 62:602-607, 2002.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 602-607
-
-
Li, L.1
Matsuoka, I.2
Suzuki, Y.3
Watanabe, Y.4
Ishibashi, T.5
Yokoyama, K.6
Maruyama, Y.7
Kimura, J.8
-
49
-
-
0037039158
-
Rac and Rho mediate opposing hormonal regulation of the ether-a-go-go-related potassium channel
-
Storey NM, O'Bryan JP, Armstrong DL. Rac and Rho mediate opposing hormonal regulation of the ether-a-go-go-related potassium channel. Curr Biol 12:27-33, 2002.
-
(2002)
Curr Biol
, vol.12
, pp. 27-33
-
-
Storey, N.M.1
O'Bryan, J.P.2
Armstrong, D.L.3
-
50
-
-
0030961897
-
The monomeric G-proteins Rac1 and/or Cdc42 are required for the inhibition of voltage-dependent calcium current by bradykinin
-
Wilk-Blaszczak MA, Singer WD, Quill T, Miller B, Frost JA, Sternweis PC, Belardetti F. The monomeric G-proteins Rac1 and/or Cdc42 are required for the inhibition of voltage-dependent calcium current by bradykinin. J Neurosci 17:4094-4100, 1997.
-
(1997)
J Neurosci
, vol.17
, pp. 4094-4100
-
-
Wilk-Blaszczak, M.A.1
Singer, W.D.2
Quill, T.3
Miller, B.4
Frost, J.A.5
Sternweis, P.C.6
Belardetti, F.7
-
51
-
-
0034253196
-
Small G-protein networks: Their crosstalk and signal cascades
-
Matozaki T, Nakanishi H, Takai Y. Small G-protein networks: their crosstalk and signal cascades. Cell Signal 12:515-524, 2000.
-
(2000)
Cell Signal
, vol.12
, pp. 515-524
-
-
Matozaki, T.1
Nakanishi, H.2
Takai, Y.3
-
52
-
-
33747184318
-
-
Santarius M, Lee CH, Anderson RA. Supervised membrane swimming: small G-protein lifeguards regulate PIPK signalling and monitor intracellular PtdIns(4,5)P2 pools. Biochem J 398:1-13, 2006.
-
Santarius M, Lee CH, Anderson RA. Supervised membrane swimming: small G-protein lifeguards regulate PIPK signalling and monitor intracellular PtdIns(4,5)P2 pools. Biochem J 398:1-13, 2006.
-
-
-
-
53
-
-
1542319943
-
Activation of type I phosphatidylinositol 4-phosphate 5-kinase isoforms by the Rho GTPases, RhoA, Rac1, and Cdc42
-
Weernink PA, Meletiadis K, Hommeltenberg S, Hinz M, Ishihara H, Schmidt M, Jakobs KH. Activation of type I phosphatidylinositol 4-phosphate 5-kinase isoforms by the Rho GTPases, RhoA, Rac1, and Cdc42. J Biol Chem 279:7840-7849, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 7840-7849
-
-
Weernink, P.A.1
Meletiadis, K.2
Hommeltenberg, S.3
Hinz, M.4
Ishihara, H.5
Schmidt, M.6
Jakobs, K.H.7
-
54
-
-
0006178818
-
Stimulation of phosphatidylinositol-4- phosphate 5-kinase by Rho-kinase
-
Weernink PAO, Schulte P, Guo Y, Wetzel J, Amano M, Kaibuchi K, Haverland S, Vo M, Schmidt M, Mayr GW, Jakobs KH. Stimulation of phosphatidylinositol-4- phosphate 5-kinase by Rho-kinase. J Biol Chem 275:10168-10174, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 10168-10174
-
-
Weernink, P.A.O.1
Schulte, P.2
Guo, Y.3
Wetzel, J.4
Amano, M.5
Kaibuchi, K.6
Haverland, S.7
Vo, M.8
Schmidt, M.9
Mayr, G.W.10
Jakobs, K.H.11
-
55
-
-
4744370340
-
Rho and Rho-kinase mediate thrombin-induced phosphatidylinositol 4-phosphate 5-kinase trafficking in platelets
-
Yang SA, Carpenter CL, Abrams CS. Rho and Rho-kinase mediate thrombin-induced phosphatidylinositol 4-phosphate 5-kinase trafficking in platelets. J Biol Chem 279:42331-42336, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 42331-42336
-
-
Yang, S.A.1
Carpenter, C.L.2
Abrams, C.S.3
-
56
-
-
0028338545
-
Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85
-
Zheng Y, Bagrodia S, Cerione RA. Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85. J Biol Chem 269:18727-18730, 1994.
-
(1994)
J Biol Chem
, vol.269
, pp. 18727-18730
-
-
Zheng, Y.1
Bagrodia, S.2
Cerione, R.A.3
-
57
-
-
0029870402
-
Rac GTPase interacts specifically with phosphatidylinositol 3-kinase
-
Bokoch GM, Vlahos CJ, Wang Y, Knaus UG, Traynor-Kaplan AE. Rac GTPase interacts specifically with phosphatidylinositol 3-kinase. Biochem J 315:775-779, 1996.
-
(1996)
Biochem J
, vol.315
, pp. 775-779
-
-
Bokoch, G.M.1
Vlahos, C.J.2
Wang, Y.3
Knaus, U.G.4
Traynor-Kaplan, A.E.5
-
58
-
-
0029023942
-
Rho family GTPases bind to phosphoinositide kinases
-
Tolias KF, Cantley LC, Carpenter CL. Rho family GTPases bind to phosphoinositide kinases. J Biol Chem 270:17656-17659, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 17656-17659
-
-
Tolias, K.F.1
Cantley, L.C.2
Carpenter, C.L.3
-
59
-
-
0035827567
-
An inhibitory role of Rho in the vasopressin-mediated translocation of aquaporin-2 into cell membranes of renal principal cells
-
Klussmann E, Tamma G, Lorenz D, Wiesner B, Maric K, Hofmann F, Aktories K, Valenti G, Rosenthal W. An inhibitory role of Rho in the vasopressin-mediated translocation of aquaporin-2 into cell membranes of renal principal cells. J Biol Chem 276:20451-20457, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 20451-20457
-
-
Klussmann, E.1
Tamma, G.2
Lorenz, D.3
Wiesner, B.4
Maric, K.5
Hofmann, F.6
Aktories, K.7
Valenti, G.8
Rosenthal, W.9
-
60
-
-
33646592231
-
Regulation of the epithelial Na+ channel (ENaC) by phosphatidylinositides
-
Pochynyuk O, Tong Q, Staruschenko A, Ma HP, Stockand JD. Regulation of the epithelial Na+ channel (ENaC) by phosphatidylinositides. Am J Physiol Renal Physiol 290:F949-F957, 2006.
-
(2006)
Am J Physiol Renal Physiol
, vol.290
-
-
Pochynyuk, O.1
Tong, Q.2
Staruschenko, A.3
Ma, H.P.4
Stockand, J.D.5
-
61
-
-
0036092076
-
The TRPM7 channel is inactivated by PIP(2) hydrolysis
-
Runnels LW, Yue L, Clapham DE. The TRPM7 channel is inactivated by PIP(2) hydrolysis. Nat Cell Biol 4:329-336, 2002.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 329-336
-
-
Runnels, L.W.1
Yue, L.2
Clapham, D.E.3
-
62
-
-
0035658684
-
Rho inhibits cAMP-induced translocation of aquaporin-2 into the apical membrane of renal cells
-
Tamma G, Klussmann E, Maric K, Aktories K, Svelto M, Rosenthal W, Valenti G. Rho inhibits cAMP-induced translocation of aquaporin-2 into the apical membrane of renal cells. Am J Physiol Renal Physiol 281:F1092-F1101, 2001.
-
(2001)
Am J Physiol Renal Physiol
, vol.281
-
-
Tamma, G.1
Klussmann, E.2
Maric, K.3
Aktories, K.4
Svelto, M.5
Rosenthal, W.6
Valenti, G.7
-
63
-
-
0037730396
-
cAMP-induced AQP2 translocation is associated with RhoA inhibition through RhoA phosphorylation and interaction with RhoGDI
-
Tamma G, Klussmann E, Procino G, Svelto M, Rosenthal W, Valenti G. cAMP-induced AQP2 translocation is associated with RhoA inhibition through RhoA phosphorylation and interaction with RhoGDI. J Cell Sci 116:1519-1525, 2003.
-
(2003)
J Cell Sci
, vol.116
, pp. 1519-1525
-
-
Tamma, G.1
Klussmann, E.2
Procino, G.3
Svelto, M.4
Rosenthal, W.5
Valenti, G.6
-
64
-
-
34347217501
-
Quantifying RhoA facilitated trafficking of the epithelial Na+ channel toward the plasma membrane with total internal reflection fluorescence-fluorescence recovery after photobleaching
-
Pochynyuk O, Staruschenko A, Bugaj V, Lagrange L, Stockand JD. Quantifying RhoA facilitated trafficking of the epithelial Na+ channel toward the plasma membrane with total internal reflection fluorescence-fluorescence recovery after photobleaching. J Biol Chem 282:14576-14585, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 14576-14585
-
-
Pochynyuk, O.1
Staruschenko, A.2
Bugaj, V.3
Lagrange, L.4
Stockand, J.D.5
-
65
-
-
0029002969
-
A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel
-
Sanguinetti MC, Jiang C, Curran ME, Keating MT. A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel. Cell 81:299-307, 1995.
-
(1995)
Cell
, vol.81
, pp. 299-307
-
-
Sanguinetti, M.C.1
Jiang, C.2
Curran, M.E.3
Keating, M.T.4
-
66
-
-
33645317063
-
hERG potassium channels and cardiac arrhythmia
-
Sanguinetti MC, Tristani-Firouzi M. hERG potassium channels and cardiac arrhythmia. Nature 440:463-469, 2006.
-
(2006)
Nature
, vol.440
, pp. 463-469
-
-
Sanguinetti, M.C.1
Tristani-Firouzi, M.2
-
67
-
-
27744520682
-
Rab proteins, connecting transport and vesicle fusion
-
Jordens I, Marsman M, Kuijl C, Neefjes J. Rab proteins, connecting transport and vesicle fusion. Traffic 6:1070-1077, 2005.
-
(2005)
Traffic
, vol.6
, pp. 1070-1077
-
-
Jordens, I.1
Marsman, M.2
Kuijl, C.3
Neefjes, J.4
-
68
-
-
33747066132
-
Rabs and their effectors: Achieving specificity in membrane traffic
-
Grosshans BL, Ortiz D, Novick P. Rabs and their effectors: achieving specificity in membrane traffic. Proc Natl Acad Sci U S A 103:11821-11827, 2006.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 11821-11827
-
-
Grosshans, B.L.1
Ortiz, D.2
Novick, P.3
-
69
-
-
33750720020
-
Regulation of epithelial ion channels by Rab GTPases
-
Saxena SK, Kaur S. Regulation of epithelial ion channels by Rab GTPases. Biochem Biophys Res Commun 351:582-587, 2006.
-
(2006)
Biochem Biophys Res Commun
, vol.351
, pp. 582-587
-
-
Saxena, S.K.1
Kaur, S.2
-
71
-
-
29644432113
-
Rab4 GTP/GDP modulates amiloride-sensitive sodium channel (ENaC) function in colonic epithelia
-
Saxena SK, Singh M, Shibata H, Kaur S, George C. Rab4 GTP/GDP modulates amiloride-sensitive sodium channel (ENaC) function in colonic epithelia. Biochem Biophys Res Commun 340:726-733, 2006.
-
(2006)
Biochem Biophys Res Commun
, vol.340
, pp. 726-733
-
-
Saxena, S.K.1
Singh, M.2
Shibata, H.3
Kaur, S.4
George, C.5
-
72
-
-
27144473630
-
Rab proteins regulate epithelial sodium channel activity in colonic epithelial HT-29 cells
-
Saxena S, Singh M, Engisch K, Fukuda M, Kaur S. Rab proteins regulate epithelial sodium channel activity in colonic epithelial HT-29 cells. Biochem Biophys Res Commun 337:1219-1223, 2005.
-
(2005)
Biochem Biophys Res Commun
, vol.337
, pp. 1219-1223
-
-
Saxena, S.1
Singh, M.2
Engisch, K.3
Fukuda, M.4
Kaur, S.5
-
73
-
-
33646087205
-
Rab27a regulates epithelial sodium channel (ENaC) activity through synaptotagmin-like protein (SLP-5) and Munc13-4 effector mechanism
-
Saxena SK, Horiuchi H, Fukuda M. Rab27a regulates epithelial sodium channel (ENaC) activity through synaptotagmin-like protein (SLP-5) and Munc13-4 effector mechanism. Biochem Biophys Res Commun 344:651-657, 2006.
-
(2006)
Biochem Biophys Res Commun
, vol.344
, pp. 651-657
-
-
Saxena, S.K.1
Horiuchi, H.2
Fukuda, M.3
-
74
-
-
33744970699
-
Rab27a negatively regulates CFTR chloride channel function in colonic epithelia: Involvement of the effector proteins in the regulatory mechanism
-
Saxena SK, Kaur S. Rab27a negatively regulates CFTR chloride channel function in colonic epithelia: involvement of the effector proteins in the regulatory mechanism. Biochem Biophys Res Commun 346:259-267, 2006.
-
(2006)
Biochem Biophys Res Commun
, vol.346
, pp. 259-267
-
-
Saxena, S.K.1
Kaur, S.2
-
75
-
-
30944450771
-
Rab4GTPase modulates CFTR function by impairing channel expression at plasma membrane
-
Saxena SK, Kaur S, George C. Rab4GTPase modulates CFTR function by impairing channel expression at plasma membrane. Biochem Biophys Res Commun 341:184-191, 2006.
-
(2006)
Biochem Biophys Res Commun
, vol.341
, pp. 184-191
-
-
Saxena, S.K.1
Kaur, S.2
George, C.3
-
77
-
-
2542480784
-
Endocytic trafficking routes of wild type and DeltaF508 cystic fibrosis transmembrane conductance regulator
-
Gentzsch M, Chang XB, Cui L, Wu Y, Ozols VV, Choudhury A, Pagano RE, Riordan JR. Endocytic trafficking routes of wild type and DeltaF508 cystic fibrosis transmembrane conductance regulator. Mol Biol Cell 15:2684-2696, 2004.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 2684-2696
-
-
Gentzsch, M.1
Chang, X.B.2
Cui, L.3
Wu, Y.4
Ozols, V.V.5
Choudhury, A.6
Pagano, R.E.7
Riordan, J.R.8
-
78
-
-
27744482654
-
The short apical membrane half-life of rescued {Delta}F508-cystic fibrosis transmembrane conductance regulator (CFTR) results from accelerated endocytosis of {Delta}F508-CFTR in polarized human airway epithelial cells
-
Swiatecka-Urban A, Brown A, Moreau-Marquis S, Renuka J, Coutermarsh B, Barnaby R, Karlson KH, Flotte TR, Fukuda M, Langford GM, Stanton BA. The short apical membrane half-life of rescued {Delta}F508-cystic fibrosis transmembrane conductance regulator (CFTR) results from accelerated endocytosis of {Delta}F508-CFTR in polarized human airway epithelial cells. J Biol Chem 280:36762-36772, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 36762-36772
-
-
Swiatecka-Urban, A.1
Brown, A.2
Moreau-Marquis, S.3
Renuka, J.4
Coutermarsh, B.5
Barnaby, R.6
Karlson, K.H.7
Flotte, T.R.8
Fukuda, M.9
Langford, G.M.10
Stanton, B.A.11
-
79
-
-
12344325458
-
RhoA GTPase regulates L-type Ca2+ currents in cardiac myocytes
-
Yatani A, Irie K, Otani T, Abdellatif M, Wei L. RhoA GTPase regulates L-type Ca2+ currents in cardiac myocytes. Am J Physiol Heart Circ Physiol 288:H650-H659, 2005.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.288
-
-
Yatani, A.1
Irie, K.2
Otani, T.3
Abdellatif, M.4
Wei, L.5
-
80
-
-
0141794172
-
Role of the small GTPase Rho in modulation of the inwardly rectifying potassium channel Kir2.1
-
Jones SV. Role of the small GTPase Rho in modulation of the inwardly rectifying potassium channel Kir2.1. Mol Pharmacol 64:987-993, 2003.
-
(2003)
Mol Pharmacol
, vol.64
, pp. 987-993
-
-
Jones, S.V.1
-
81
-
-
33745806229
-
Regulation of a family of inwardly rectifying potassium channels (Kir2) by the m1 muscarinic receptor and the small GTPase Rho
-
Rossignol TM, Jones SV. Regulation of a family of inwardly rectifying potassium channels (Kir2) by the m1 muscarinic receptor and the small GTPase Rho. Pflugers Arch Eur J Physiol 452:164-174, 2006.
-
(2006)
Pflugers Arch Eur J Physiol
, vol.452
, pp. 164-174
-
-
Rossignol, T.M.1
Jones, S.V.2
-
82
-
-
33749355316
-
Cholesterol modulates the volume-regulated anion current in Ehrlich-Lettre ascites cells via effects on Rho and F-actin
-
Klausen TK, Hougaard C, Hoffmann EK, Pedersen SF. Cholesterol modulates the volume-regulated anion current in Ehrlich-Lettre ascites cells via effects on Rho and F-actin. Am J Physiol Cell Physiol 291:C757-C771, 2006.
-
(2006)
Am J Physiol Cell Physiol
, vol.291
-
-
Klausen, T.K.1
Hougaard, C.2
Hoffmann, E.K.3
Pedersen, S.F.4
-
83
-
-
0034817372
-
Regulation of I(Cl,swell) in neuroblastoma cells by G protein signaling pathways
-
Estevez AY, Bond T, Strange K. Regulation of I(Cl,swell) in neuroblastoma cells by G protein signaling pathways. Am J Physiol Cell Physiol 281:C89-C98, 2001.
-
(2001)
Am J Physiol Cell Physiol
, vol.281
-
-
Estevez, A.Y.1
Bond, T.2
Strange, K.3
-
84
-
-
17444451283
-
RhoA exerts a permissive effect on volume-regulated anion channels in vascular endothelial cells
-
Carton I, Trouet D, Hermans D, Barth H, Aktories K, Droogmans G, Jorgensen NK, Hoffmann EK, Nilius B, Eggermont J. RhoA exerts a permissive effect on volume-regulated anion channels in vascular endothelial cells. Am J Physiol Cell Physiol 283:C115-C125, 2002.
-
(2002)
Am J Physiol Cell Physiol
, vol.283
-
-
Carton, I.1
Trouet, D.2
Hermans, D.3
Barth, H.4
Aktories, K.5
Droogmans, G.6
Jorgensen, N.K.7
Hoffmann, E.K.8
Nilius, B.9
Eggermont, J.10
-
85
-
-
0032518971
-
Regulation of a swelling-activated chloride current in bovine endothelium by protein tyrosine phosphorylation and G proteins
-
Voets T, Manolopoulos V, Eggermont J, Ellory C, Droogmans G, Nilius B. Regulation of a swelling-activated chloride current in bovine endothelium by protein tyrosine phosphorylation and G proteins. J Physiol 506:341-352, 1998.
-
(1998)
J Physiol
, vol.506
, pp. 341-352
-
-
Voets, T.1
Manolopoulos, V.2
Eggermont, J.3
Ellory, C.4
Droogmans, G.5
Nilius, B.6
-
86
-
-
0033118584
-
Role of Rho and Rho kinase in the activation of volume-regulated anion channels in bovine endothelial cells
-
Nilius B, Voets T, Prenen J, Barth H, Aktories K, Kaibuchi K, Droogmans G, Eggermont J. Role of Rho and Rho kinase in the activation of volume-regulated anion channels in bovine endothelial cells. J Physiol 516:67-74, 1999.
-
(1999)
J Physiol
, vol.516
, pp. 67-74
-
-
Nilius, B.1
Voets, T.2
Prenen, J.3
Barth, H.4
Aktories, K.5
Kaibuchi, K.6
Droogmans, G.7
Eggermont, J.8
-
87
-
-
0029833712
-
Activation of the osmo-sensitive chloride conductance involves P21rho and is accompanied by a transient reorganization of the F-actin cytoskeleton
-
Tilly BC, Edixhoven MJ, Tertoolen LG, Morii N, Saitoh Y, Narumiya S, de Jonge HR. Activation of the osmo-sensitive chloride conductance involves P21rho and is accompanied by a transient reorganization of the F-actin cytoskeleton. Mol Biol Cell 7:1419-1427, 1996.
-
(1996)
Mol Biol Cell
, vol.7
, pp. 1419-1427
-
-
Tilly, B.C.1
Edixhoven, M.J.2
Tertoolen, L.G.3
Morii, N.4
Saitoh, Y.5
Narumiya, S.6
de Jonge, H.R.7
-
88
-
-
13544273548
-
Regulation of cystic fibrosis transmembrane regulator trafficking and protein expression by a Rho family small GTPase TC10
-
Cheng J, Wang H, Guggino WB. Regulation of cystic fibrosis transmembrane regulator trafficking and protein expression by a Rho family small GTPase TC10. J Biol Chem 280:3731-3739, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 3731-3739
-
-
Cheng, J.1
Wang, H.2
Guggino, W.B.3
|