Determination of rifalazil, a potent antibacterial agent, in human plasma by liquid-liquid extraction and LC-MS/MS

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 859, Issue 1, 2007, Pages 103-110

  Larsson, Marita ^a   Michaelis, Arthur F ^a   Zhu, Yongdong ^b   Ramu, Kumar ^b  

^a ActivBiotics Inc   (United States)

^b Quest Pharmaceutical Services   (United States)

Author keywords

ABI 1648; Electrospray; Human plasma; Isotope labeled internal standard; KRM 1648; Quantification; Rifalazil

Indexed keywords

BIOASSAY; ETHERS; EXTRACTION; PLASMA (HUMAN);

ISOTOPE LABELED INTERNAL STANDARD; RIFALAZIL;

BACTERIA;

ANTIINFECTIVE AGENT; RIFALAZIL;

ARTICLE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; PRIORITY JOURNAL; QUALITY CONTROL; QUANTITATIVE ANALYSIS; TANDEM MASS SPECTROMETRY;

ANTI-BACTERIAL AGENTS; CALIBRATION; CHROMATOGRAPHY, LIQUID; HUMANS; REFERENCE STANDARDS; RIFAMYCINS; TANDEM MASS SPECTROMETRY;

EID: 35548946175     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.09.013     Document Type: Article

References (10)

1. Rothstein D.M., Hartman A.D., Cynamon M.H., and Eisenstein B.I. Exp. Opin. Invest. Drugs 12 (2003) 255
2. Stamm W.E., Batteiger B.E., McCormack W.M., Totten P.A., Sternlicht A., and Kivel N.M. Sex. Transm. Dis. 34 (2007) 545
3. Mae T., Hosoe E., Yamamoto T., and Hidaka T. Xenobiotica 28 (1998) 759
4. Rothstein D.M., Shalish C., Murphy C.K., Sternlicht A., and Campbell L.A. Exp. Opin. Invest. Drugs 15 (2006) 603
5. Chen Y.-X., Cabana B., Robertson L., Johnson C., and Kivel N. J. Clin. Pharmacol. 47 (2007) 841
6. Hosoe K., Konishi E., Hidaka T., Yamane T., Yamashita K., and Ohashi T. J. Chromatogr. B 653 (1994) 177
7. Hosoe K., Mae T., Konishi E., Fujii K., Yamashita K., Yamane T., Hidaka T., and Ohashi T. Antimicrob. Agents Chemother. 40 (1996) 2749
8. C.T. Vishwanathan, S. Bansal, B. Booth, A.J. DeStefano, M.J. Rose, J. Sailstad, V.P. Shah, J.P. Skelly, P.G. Swann, R. Weiner, Workshop/Conference Report, Quantitative Bioanalytical Methods Validation and Implementation: Best Practices for Chromatographic and Ligand Binding Assays, AAPS J. 9 (1) (2007) (article 4, http://www.aapsj.org).
9. M. Larsson, F. Han, J. Pharm. Biomed. Anal. (2007) doi:10.1016/j.jpba.2007.09.006.
10. Matuszewski B.K. J. Chromatogr. B 830 (2006) 293