A non-radioactive method for detecting neutralizing antibodies against therapeutic proteins in serum

Journal of Pharmaceutical and Biomedical Analysis

Volumn 45, Issue 4, 2007, Pages 583-589

  Wala, Iwona ^a   Swanson, Steven J ^a   Jing, Shuqian ^a  

^a AMGEN INC   (United States)

Author keywords

Cell based bioassay; Metabolic activity; Neutralizing antibodies; Non radioactive method

Indexed keywords

ERYTHROPOIETIN; NEUTRALIZING ANTIBODY; RECOMBINANT ERYTHROPOIETIN; RECOMBINANT GAMMA INTERFERON;

ANTIBODY DETECTION; ANTIBODY PRODUCTION; APOPTOSIS; ARTICLE; BIOASSAY; CELL CULTURE; CELL LINE; CELL METABOLISM; CELL PROLIFERATION; CONTROLLED STUDY; CULTURE MEDIUM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SERUM;

ANTIBODIES; APOPTOSIS; BIOLOGICAL ASSAY; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; EPOETIN ALFA; GRANULOCYTE MACROPHAGE COLONY-STIMULATING FACTORS, RECOMBINANT; HUMANS; INTERFERON-GAMMA, RECOMBINANT; NEUTRALIZATION TESTS; RECOMBINANT PROTEINS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 35548945343     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2007.08.005     Document Type: Article

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