Development and validation of a cell-based bioassay for the detection of neutralizing antibodies against recombinant human erythropoietin in clinical studies

Journal of Immunological Methods

Volumn 293, Issue 1-2, 2004, Pages 115-126

  Wei, Xin ^a   Swanson, Steven J ^a   Gupta, Shalini ^a  

^a AMGEN INC   (United States)

Author keywords

32D cell line; Murine interleukin 3; Proliferation; Pure red cell aplasia; Serum based bioassay

Indexed keywords

CELL DNA; ERYTHROPOIETIN RECEPTOR; INTERLEUKIN 3; NEUTRALIZING ANTIBODY; RECOMBINANT ERYTHROPOIETIN; THYMIDINE; TRITIUM;

ACCURACY; ANIMAL CELL; ANIMAL CELL CULTURE; ANTIBODY DETECTION; ARTICLE; BIOASSAY; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; FREEZING; MOUSE; NONHUMAN; PRIORITY JOURNAL; SERUM; THAWING; VALIDATION PROCESS;

ANTIBODIES; BIOLOGICAL ASSAY; CELL DIVISION; CELL LINE; ERYTHROPOIETIN; HUMANS; INTERLEUKIN-3;

MURINAE;

EID: 7944234691     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2004.07.007     Document Type: Article

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