{A figure is presented}Adult Autoimmune Enteropathy: Mayo Clinic Rochester Experience

Clinical Gastroenterology and Hepatology

Volumn 5, Issue 11, 2007, Pages 1282-1290

  Akram, Salma ^a   Murray, Joseph A ^a   Pardi, Darrell S ^a   Alexander, Glenn L ^a   Schaffner, John A ^a   Russo, Pierre A ^c   Abraham, Susan C ^b  

^a MAYO CLINIC   (United States)

^b Mayo Clinic   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; BUDESONIDE; CYCLOSPORIN; DIPHENOXYLATE; IMMUNOGLOBULIN; INFLIXIMAB; MERCAPTOPURINE; METHYLPREDNISOLONE; METRONIDAZOLE; PREDNISONE; STEROID; TACROLIMUS; ANTIBODY; IMMUNOSUPPRESSIVE AGENT;

ADULT; AGED; ARTICLE; AUTOIMMUNE DISEASE; CELIAC DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DEMOGRAPHY; DIARRHEA; DISEASE PREDISPOSITION; DRUG MEGADOSE; ENTEROPATHY; FEMALE; FOLLOW UP; GLUTEN FREE DIET; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INTESTINE BIOPSY; MALE; MALNUTRITION; MONOTHERAPY; T LYMPHOCYTE RECEPTOR GENE; TREATMENT OUTCOME; WEIGHT REDUCTION; ATROPHY; BIOPSY; BLOOD; DIGESTIVE TRACT ENDOSCOPY; GOBLET CELL; IMMUNOLOGY; INTESTINE CELL; LYMPHOCYTE; MIDDLE AGED; PATHOLOGY; PROSPECTIVE STUDY; RETROSPECTIVE STUDY; SMALL INTESTINE;

ADULT; AGED; ANTIBODIES; ATROPHY; AUTOIMMUNE DISEASES; BIOPSY; DIARRHEA; ENDOSCOPY, DIGESTIVE SYSTEM; ENTEROCYTES; FEMALE; FOLLOW-UP STUDIES; GOBLET CELLS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTESTINAL DISEASES; INTESTINE, SMALL; LYMPHOCYTES; MALE; MALNUTRITION; MIDDLE AGED; PROSPECTIVE STUDIES; RETROSPECTIVE STUDIES; WEIGHT LOSS;

EID: 35548937748     PISSN: 15423565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cgh.2007.05.013     Document Type: Article

References (50)

1. Walker-Smith J.A., Unsworth D.J., Hutchins P., et al. Autoantibodies against gut epithelium in child with small-intestinal enteropathy. Lancet 1 (1982) 566-567
2. Unsworth D.J., and Walker-Smith J.A. Autoimmunity in diarrhoeal disease. J Pediatr Gastroenterol Nutr 4 (1985) 375-380
3. Ruemmele F.M., Brousse N., and Goulet O. Autoimmune enteropathy: molecular concepts. Curr Opin Gastroenterol 20 (2004) 587-591
4. Biagi F., and Corazza G.R. Defining gluten refractory enteropathy. Eur J Gastroenterol Hepatol 13 (2001) 561-565
5. Bousvaros A., Leichtner A.M., Book L., et al. Treatment of pediatric autoimmune enteropathy with tacrolimus (FK506). Gastroenterology 111 (1996) 237-243
6. Daum S., Sahin E., Jansen A., et al. Adult autoimmune enteropathy treated successfully with tacrolimus. Digestion 68 (2003) 86-90
7. Oliva-Hemker M.M., Loeb D.M., Abraham S.C., et al. Remission of severe autoimmune enteropathy after treatment with high-dose cyclophosphamide. J Pediatr Gastroenterol Nutr 36 (2003) 639-643
8. Sanderson I.R., Phillips A.D., Spencer J., et al. Response to autoimmune enteropathy to cyclosporin A therapy. Gut 32 (1991) 1421-1425
9. Vanderhoof J.A., and Young R.J. Autoimmune enteropathy in a child: response to infliximab therapy. J Pediatr Gastroenterol Nutr 34 (2002) 312-316
10. Sykora J., Varvarovska J., Stozicky F., et al. [Autoimmune enteropathy with onset in early infancy: clinico-morphologic and immunologic manifestations]. Cas Lek Cesk 141 (2002) 646-650
11. Savage M.O., Mirakian R., Wozniak E.R., et al. Specific autoantibodies to gut epithelium in two infants with severe protracted diarrhoea. J Pediatr Gastroenterol Nutr 4 (1985) 187-195
12. Mirakian R., Richardson A., Milla P.J., et al. Protracted diarrhoea of infancy: evidence in support of an autoimmune variant. Br Med J (Clin Res Ed) 293 (1986) 1132-1136
13. Hill S.M., Milla P.J., Bottazzo G.F., et al. Autoimmune enteropathy and colitis: is there a generalised autoimmune gut disorder?. Gut 32 (1991) 36-42
14. Leon F., Olivencia P., Rodriguez-Pena R., et al. Clinical and immunological features of adult-onset generalized autoimmune gut disorder. Am J Gastroenterol 99 (2004) 1563-1571
15. Corazza G.R., Biagi F., Volta U., et al. Autoimmune enteropathy and villous atrophy in adults. Lancet 350 (1997) 106-109
16. McCune C.A., Hughes S., and Unsworth D.J. Thymoma, autoimmunity and fatal immunodeficiency. Q J M 93 (2000) 559-560
17. Casis B., Fernandez-Vazquez I., Barnardos E., et al. Autoimmune enteropathy in an adult with autoimmune multisystemic involvement. Scand J Gastroenterol 37 (2002) 1012-1016
18. Carroccio A., Volta U., Di Prima L., et al. Autoimmune enteropathy and colitis in an adult patient. Dig Dis Sci 48 (2003) 1600-1606
19. Mais D.D., Mulhall B.P., Adolphson K.R., et al. Thymoma-associated autoimmune enteropathy: a report of two cases. Am J Clin Pathol 112 (1999) 810-815
20. Mitomi H., Tanabe S., Igarashi M., et al. Autoimmune enteropathy with severe atrophic gastritis and colitis in an adult: proposal of a generalized autoimmune disorder of the alimentary tract. Scand J Gastroenterol 33 (1998) 716-720
21. Al Khalidi H., Kandel G., and Streutker C.J. Enteropathy with loss of enteroendocrine and paneth cells in a patient with immune dysregulation: a case of adult autoimmune enteropathy. Hum Pathol 37 (2006) 373-376
22. Russo P.A., and Alvarez F. Autoimmune enteropathy: a review. Clinical and Applied Immunology Reviews 2 (2002) 203-216
23. Sakaguchi S. Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat Immunol 6 (2005) 345-352
24. Yagi H., Nomura T., Nakamura K., et al. Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells. Int Immunol 16 (2004) 1643-1656
25. Sakaguchi S. The origin of FOXP3-expressing CD4+ regulatory T cells: thymus or periphery. J Clin Invest 112 (2003) 1310-1312
26. Schubert L.A., Jeffery E., Zhang Y., et al. Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation. J Biol Chem 276 (2001) 37672-37679
27. Brunkow M.E., Jeffery E.W., Hjerrild K.A., et al. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat Genet 27 (2001) 68-73
28. De Benedetti F., Insalaco A., Diamanti A., et al. Mechanistic associations of a mild phenotype of immunodysregulation, polyendocrinopathy, enteropathy, X-linked syndrome. Clin Gastroenterol Hepatol 4 (2006) 653-659
29. Wildin R.S., and Freitas A. IPEX and FOXP3: clinical and research perspectives. J Autoimmunity 25 Suppl (2005) 56-62
30. Lachaux A. Autoimmune enteropathy. Arch Pediatr 3 (1996) 261-266
31. Russo P.A., Brochu P., Seidman E.G., et al. Autoimmune enteropathy. Pediatr Dev Pathol 2 (1999) 65-71
32. Martin-Villa J.M., Camblor S., Costa R., et al. Gut epithelial cell autoantibodies in AIDS pathogenesis. Lancet 342 (1993) 380
33. Hibi T., Ohara M., Kobayashi K., et al. Enzyme linked immunosorbent assay (ELISA) and immunoprecipitation studies on anti-goblet cell antibody using a mucin producing cell line in patients with inflammatory bowel disease. Gut 35 (1994) 224-230
34. Folwaczny C., Noehl N., Tschop K., et al. Goblet cell autoantibodies in patients with inflammatory bowel disease and their first-degree relatives. Gastroenterology 113 (1997) 101-106
35. Rogahn D., Smith C.P., and Thomas A. Autoimmune enteropathy with goblet-cell antibodies. J R Soc Med 92 (1999) 311-312
36. Moore L., Xu X., Davidson G., et al. Autoimmune enteropathy with anti-goblet cell antibodies. Hum Pathol 26 (1995) 1162-1168
37. Unsworth J., Hutchins P., Mitchell J., et al. Flat small intestinal mucosa and autoantibodies against the gut epithelium. J Pediatr Gastroenterol Nutr 1 (1982) 503-513
38. Kalha I., and Sellin J.H. Common variable immunodeficiency and the gastrointestinal tract. Curr Gastroenterol Rep 6 (2004) 377-383
39. Ciccocioppo R., D'Alo S., Di Sabatino A., et al. Mechanisms of villous atrophy in autoimmune enteropathy and coeliac disease. Clin Exp Immunol 128 (2002) 88-93
40. Washington K., Stenzel T.T., Buckley R.H., et al. Gastrointestinal pathology in patients with common variable immunodeficiency and X-linked agammaglobulinemia. Am J Surg Pathol 20 (1996) 1240-1252
41. Veress B., Franzen L., Bodin L., et al. Duodenal intraepithelial lymphocyte-count revisited. Scand J Gastroenterol 39 (2004) 138-144
42. Cuenod B., Brousse N., Goulet O., et al. Classification of intractable diarrhea in infancy using clinical and immunohistological criteria. Gastroenterology 99 (1990) 1037-1043
43. Culliford A.N., and Green P.H. Refractory sprue. Curr Gastroenterol Rep 5 (2003) 373-378
44. Green P.H., and Jabri B. Coeliac disease. Lancet 362 (2003) 383-391
45. Cellier C., Delabesse E., Helmer C., et al. Refractory sprue, coeliac disease, and enteropathy-associated T-cell lymphoma: French Coeliac Disease Study Group. Lancet 356 (2000) 203-208
46. Patey-Mariaud De Serre N., Cellier C., Jabri B., et al. Distinction between coeliac disease and refractory sprue: a simple immunohistochemical method. Histopathology 37 (2000) 70-77
47. Wright D.H. The major complications of coeliac disease. Baillieres Clin Gastroenterol 9 (1995) 351-369
48. Brousse N., and Meijer J.W. Malignant complications of coeliac disease. Best Pract Res Clin Gastroenterol 19 (2005) 401-412
49. Elwing J.E., and Clouse R.E. Adult-onset autoimmune enteropathy in the setting of thymoma successfully treated with infliximab. Dig Dis Sci 50 (2005) 928-932
50. Rolny P., Sigurjonsdottir H.A., Remotti H., et al. Role of immunosuppressive therapy in refractory sprue-like disease. Am J Gastroenterol 94 (1999) 219-225