Radiocurability by Targeting Tumor Necrosis Factor-α Using a Bispecific Antibody in Carcinoembryonic Antigen Transgenic Mice

International Journal of Radiation Oncology Biology Physics

Volumn 69, Issue 4, 2007, Pages 1231-1237

  Larbouret, Christel ^a   Robert, Bruno ^a   Linard, Christine ^b   Teulon, Isabelle ^a   Gourgou, Sophie ^c   Bibeau, Frederic ^c   Martineau, Pierre ^c   Santoro, Lore ^a,c   Pouget, Jean Pierre ^a   Pelegrin, Andre ^a   Azria, David ^a,c  

^a UNIV MONTPELLIER   (France)

^b INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE IRSN   (France)

^c CENTRE VAL D AURELLE   (France)

Author keywords

Bispecific antibody; CEA transgenic mice; Radiotherapy enhancement; Synergism; Tumor necrosis factor

Indexed keywords

ANTIBODIES; ANTIGENS; MEDICAL IMAGING; RADIOTHERAPY; RNA;

BISPECIFIC ANTIBODY; CEA TRANSGENIC MICE; RADIOTHERAPY ENHANCEMENT; SYNERGISM; TUMOR NECROSIS FACTOR Α;

TUMORS;

BISPECIFIC ANTIBODY; CARCINOEMBRYONIC ANTIGEN; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER RADIOTHERAPY; CANCER SURVIVAL; CLONOGENIC ASSAY; COLON CARCINOMA; CONTROL GROUP; CONTROLLED STUDY; FEMALE; GENETIC TRANSFECTION; HISTOLOGY; IMMUNOCOMPETENT CELL; IN VITRO STUDY; IN VIVO STUDY; MONOTHERAPY; MOUSE; NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; RADIATION DOSE; STATISTICAL SIGNIFICANCE; TRANSGENIC MOUSE; TREATMENT RESPONSE;

ANIMALS; ANTIBODIES, BISPECIFIC; CARCINOEMBRYONIC ANTIGEN; CELL SURVIVAL; COLONIC NEOPLASMS; COMBINED MODALITY THERAPY; DRUG EVALUATION, PRECLINICAL; HUMANS; IMMUNOCOMPROMISED HOST; MICE; MICE, TRANSGENIC; RANDOM ALLOCATION; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA; TUMOR STEM CELL ASSAY;

EID: 35448985037     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2007.07.2372     Document Type: Article

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