-
1
-
-
33745042439
-
Oral 5-aminosalicylic acid for induction of remission in ulcerative colitis
-
2): CD000543.
-
Sutherland L, Macdonald JK. Oral 5-aminosalicylic acid for induction of remission in ulcerative colitis. Cochrane Database Syst Rev 2006 (2): CD000543.
-
(2006)
Cochrane Database Syst Rev
-
-
Sutherland, L.1
MacDonald, J.K.2
-
2
-
-
33745042439
-
Oral 5-aminosalicylic acid for maintenance of remission in ulcerative colitis
-
2): CD000544.
-
Sutherland L, Macdonald JK. Oral 5-aminosalicylic acid for maintenance of remission in ulcerative colitis. Cochrane Database Syst Rev 2006 (2): CD000544.
-
(2006)
Cochrane Database Syst Rev
-
-
Sutherland, L.1
MacDonald, J.K.2
-
3
-
-
0023100439
-
Metabolism and urinary excretion of 5-amino salicylic acid in healthy volunteers when given intravenously or released for absorption at different sites in the gastrointestinal tract
-
Myers B, Evans DNW, Rhodes J, et al. Metabolism and urinary excretion of 5-amino salicylic acid in healthy volunteers when given intravenously or released for absorption at different sites in the gastrointestinal tract. Gut 1987 28 : 196 200.
-
(1987)
Gut
, vol.28
, pp. 196-200
-
-
Myers, B.1
Evans, D.N.W.2
Rhodes, J.3
-
4
-
-
6844237647
-
And the Abacus Investigator Group. Balsalazide is more effective and better tolerated than mesalamine in the treatment of acute ulcerative colitis
-
Green JRB, Lobo AJ, Holdsworth CD, et al. and the Abacus Investigator Group. Balsalazide is more effective and better tolerated than mesalamine in the treatment of acute ulcerative colitis. Gastroenterology 1998 114 : 15 22.
-
(1998)
Gastroenterology
, vol.114
, pp. 15-22
-
-
Green, J.R.B.1
Lobo, A.J.2
Holdsworth, C.D.3
-
5
-
-
0036082021
-
A randomized, double blind, dose-response comparison of balsalazide (6.75 g), balsalazide (2.25 g), and mesalamine (2.4 g) in the treatment of active, mild-to-moderate ulcerative colitis
-
Levine DS, Riff DS, Pruitt R, et al. A randomized, double blind, dose-response comparison of balsalazide (6.75 g), balsalazide (2.25 g), and mesalamine (2.4 g) in the treatment of active, mild-to-moderate ulcerative colitis. Am J Gastroenterol 2002 97 : 1398 407.
-
(2002)
Am J Gastroenterol
, vol.97
, pp. 1398-407
-
-
Levine, D.S.1
Riff, D.S.2
Pruitt, R.3
-
6
-
-
0036897005
-
Balsalazide is superior to mesalamine in the time to improvement of signs and symptoms of acute mild-to-moderate ulcerative colitis
-
Pruitt R, Hanson J, Safdi M, et al. Balsalazide is superior to mesalamine in the time to improvement of signs and symptoms of acute mild-to-moderate ulcerative colitis. Am J Gastroenterol 2002 97 : 3078 86.
-
(2002)
Am J Gastroenterol
, vol.97
, pp. 3078-86
-
-
Pruitt, R.1
Hanson, J.2
Safdi, M.3
-
7
-
-
35448965620
-
-
Pentasa® [package insert]. PA: Shire US Inc
-
Pentasa® [package insert]. Wayne, PA : Shire US Inc 2007.
-
(2007)
Wayne
-
-
-
8
-
-
35448970198
-
-
Asacol® [package insert]. OH: Procter & Gamble Pharmaceuticals, Inc
-
Asacol® [package insert]. Cincinnati, OH : Procter & Gamble Pharmaceuticals, Inc 2006.
-
(2006)
Cincinnati
-
-
-
9
-
-
35448999692
-
-
LialdaTM [package insert]. PA: Shire US Inc
-
LialdaTM [package insert]. Wayne, PA : Shire US Inc 2007.
-
(2007)
Wayne
-
-
-
10
-
-
35448964742
-
-
Colazal® [package insert]. NC: Salix Pharmaceuticals, Inc
-
Colazal® [package insert]. Morrisville, NC : Salix Pharmaceuticals, Inc 2007.
-
(2007)
Morrisville
-
-
-
11
-
-
3843109109
-
Ulcerative colitis practice guidelines in adults (update): American College of Gastroenterology, Practice Parameters Committee
-
Kornbluth A, Sachar DB. Ulcerative colitis practice guidelines in adults (update): American College of Gastroenterology, Practice Parameters Committee. Am J Gastroenterol 2004 99 : 1371 85.
-
(2004)
Am J Gastroenterol
, vol.99
, pp. 1371-85
-
-
Kornbluth, A.1
Sachar, D.B.2
-
12
-
-
35448949553
-
-
Poster presented at: Digestive Disease Week; May 19-22, San Francisco, CA.
-
Pruitt R, Levine DS, Safdi M, et al. Balsalazide as alternative therapy to mesalamine dose-escalation for acute, mild to moderate ulcerative colitis. Poster presented at: Digestive Disease Week; May 19-22, 2002 San Francisco, CA.
-
(2002)
Balsalazide As Alternative Therapy to Mesalamine Dose-escalation for Acute, Mild to Moderate Ulcerative Colitis.
-
-
Pruitt, R.1
Levine, D.S.2
Safdi, M.3
-
13
-
-
27644504588
-
Design issues and outcomes in IBD clinical trials
-
Sands BE, Abreu MT, Ferry GD, et al. Design issues and outcomes in IBD clinical trials. Inflamm Bowel Dis 2005 11 (Suppl. 1 S22 8.
-
(2005)
Inflamm Bowel Dis
, vol.11
, Issue.1
-
-
Sands, B.E.1
Abreu, M.T.2
Ferry, G.D.3
-
14
-
-
0027292761
-
® Study Group. Mesalamine capsules for treatment of active ulcerative colitis: Results of a controlled trial
-
® Study Group. Mesalamine capsules for treatment of active ulcerative colitis: results of a controlled trial. Am J Gastroenterol 1993 88 : 1188 97.
-
(1993)
Am J Gastroenterol
, vol.88
, pp. 1188-97
-
-
Hanauer, S.1
Schwartz, J.2
Robinson, M.3
-
15
-
-
0023521441
-
Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis
-
Schroeder KW, Tremaine WJ, Ilstrup DM. Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. N Engl J Med 1987 317 : 1625 9.
-
(1987)
N Engl J Med
, vol.317
, pp. 1625-9
-
-
Schroeder, K.W.1
Tremaine, W.J.2
Ilstrup, D.M.3
-
16
-
-
0025779674
-
Oral mesalamine (Asacol) for mildly to moderately active ulcerative colitis: A multicenter study
-
Sninsky CA, Cort DH, Shanahan F, et al. Oral mesalamine (Asacol) for mildly to moderately active ulcerative colitis: a multicenter study. Ann Intern Med 1991 115 : 350 5.
-
(1991)
Ann Intern Med
, vol.115
, pp. 350-5
-
-
Sninsky, C.A.1
Cort, D.H.2
Shanahan, F.3
-
17
-
-
33644653559
-
Delayed-release oral mesalamine at 4.8 g/day (800 mg tablet) for the treatment of moderately active ulcerative colitis: The ASCEND II trial
-
Hanauer SB, Sandborn WJ, Kornbluth A, et al. Delayed-release oral mesalamine at 4.8 g/day (800 mg tablet) for the treatment of moderately active ulcerative colitis: the ASCEND II trial. Am J Gastroenterol 2005 100 : 2478 85.
-
(2005)
Am J Gastroenterol
, vol.100
, pp. 2478-85
-
-
Hanauer, S.B.1
Sandborn, W.J.2
Kornbluth, A.3
-
18
-
-
33748648599
-
Once daily MMX mesalazine for the treatment of mild-to-moderate ulcerative colitis: A phase II, dose-ranging study
-
D'Haens G, Hommes D, Engels L, et al. Once daily MMX mesalazine for the treatment of mild-to-moderate ulcerative colitis: a phase II, dose-ranging study. Aliment Pharmacol Ther 2006 24 : 1087 97.
-
(2006)
Aliment Pharmacol Ther
, vol.24
, pp. 1087-97
-
-
D'Haens, G.1
Hommes, D.2
Engels, L.3
-
19
-
-
33846213645
-
Once-daily, high-concentration MMX mesalamine in active ulcerative colitis
-
Kamm MA, Sandborn WJ, Gassull M, et al. Once-daily, high-concentration MMX mesalamine in active ulcerative colitis. Gastroenterology 2007 132 : 66 75.
-
(2007)
Gastroenterology
, vol.132
, pp. 66-75
-
-
Kamm, M.A.1
Sandborn, W.J.2
Gassull, M.3
-
20
-
-
33846242590
-
Effect of once- or twice-daily MMX mesalamine (SPD476) for the induction of remission of mild to moderately active ulcerative colitis
-
Lichtenstein GR, Kamm MA, Boddu P, et al. Effect of once- or twice-daily MMX mesalamine (SPD476) for the induction of remission of mild to moderately active ulcerative colitis. Clin Gastroenterol Hepatol 2007 5 : 95 102.
-
(2007)
Clin Gastroenterol Hepatol
, vol.5
, pp. 95-102
-
-
Lichtenstein, G.R.1
Kamm, M.A.2
Boddu, P.3
-
21
-
-
0015916139
-
Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype
-
Das KM, Eastwood MA, McManus JPA, Sircus W. Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype. N Engl J Med 1973 289 : 491 5.
-
(1973)
N Engl J Med
, vol.289
, pp. 491-5
-
-
Das, K.M.1
Eastwood, M.A.2
McManus, J.P.A.3
Sircus, W.4
-
22
-
-
0036116464
-
Review article: Monitoring for drug side-effects in inflammatory bowel disease
-
Cunliffe RN, Scott BB. Review article: monitoring for drug side-effects in inflammatory bowel disease. Aliment Pharmacol Ther 2002 16 : 647 62.
-
(2002)
Aliment Pharmacol Ther
, vol.16
, pp. 647-62
-
-
Cunliffe, R.N.1
Scott, B.B.2
-
23
-
-
0023618491
-
Olsalazine sodium in the treatment of ulcerative colitis among patients intolerant of sulfasalazine: A prospective, randomized, placebo-controlled, double-blind, dose-ranging clinical trial
-
Meyers S, Sachar DB, Present DH, Janowitz HD. Olsalazine sodium in the treatment of ulcerative colitis among patients intolerant of sulfasalazine: a prospective, randomized, placebo-controlled, double-blind, dose-ranging clinical trial. Gastroenterology 1987 93 : 1255 62.
-
(1987)
Gastroenterology
, vol.93
, pp. 1255-62
-
-
Meyers, S.1
Sachar, D.B.2
Present, D.H.3
Janowitz, H.D.4
-
24
-
-
35448967881
-
-
Presented at: World Congress of Gastroenterology; September 10-14, Montreal, Canada.
-
Sandborn WJ, Stone CD, Papadakis KA, Ajayi FO, Nesbitt JD, Regalli G. Assessment of systemic exposure following oral administration of mesalamine as an 800 mg tablet (4.8 g/day) or a 400 mg tablet (2.4 g/day): analysis of combined data from two randomized clinical trials in patients with ulcerative colitis (abstract R.0472). Presented at: World Congress of Gastroenterology; September 10-14, 2005 Montreal, Canada.
-
(2005)
Assessment of Systemic Exposure Following Oral Administration of Mesalamine As An 800 Mg Tablet (4.8 G/day) or a 400 Mg Tablet (2.4 G/day): Analysis of Combined Data from Two Randomized Clinical Trials in Patients with Ulcerative Colitis (Abstract R.0472).
-
-
Sandborn, W.J.1
Stone, C.D.2
Papadakis, K.A.3
Ajayi, F.O.4
Nesbitt, J.D.5
Regalli, G.6
-
25
-
-
0034074650
-
Dose loading with delayed-release mesalazine: A study of tissue drug concentrations and standard pharmacokinetic parameters
-
Hussain FN, Ajjan RA, Riley SA. Dose loading with delayed-release mesalazine: a study of tissue drug concentrations and standard pharmacokinetic parameters. J Clin Pharmacol 2000 49 : 323 30.
-
(2000)
J Clin Pharmacol
, vol.49
, pp. 323-30
-
-
Hussain, F.N.1
Ajjan, R.A.2
Riley, S.A.3
-
26
-
-
0033371888
-
Systemic levels of free 5-aminosalicyclic acid depend on the nature of the 5-aminosalicyclic acid derivative and not on disease activity or extent in patients with inflammatory bowel disease
-
Mahmud N, Weir DG, Kelleher D. Systemic levels of free 5-aminosalicyclic acid depend on the nature of the 5-aminosalicyclic acid derivative and not on disease activity or extent in patients with inflammatory bowel disease. Ir J Med Sci 1999 168 : 228 32.
-
(1999)
Ir J Med Sci
, vol.168
, pp. 228-32
-
-
Mahmud, N.1
Weir, D.G.2
Kelleher, D.3
-
27
-
-
0030847141
-
Renal tubular dysfunction in patients with inflammatory bowel disease treated with aminosalicylate
-
Schreiber S, Hämling J, Zehnter E, et al. Renal tubular dysfunction in patients with inflammatory bowel disease treated with aminosalicylate. Gut 1997 40 : 761 6.
-
(1997)
Gut
, vol.40
, pp. 761-6
-
-
Schreiber, S.1
Hämling, J.2
Zehnter, E.3
-
28
-
-
0034890464
-
Measurement of colonic mucosal concentrations of 5-aminosalicylic acid is useful for estimating its therapeutic efficacy in distal ulcerative colitis: Comparison of orally administered mesalamine and sulfasalazine
-
Naganuma M, Iwao Y, Ogata H, et al. Measurement of colonic mucosal concentrations of 5-aminosalicylic acid is useful for estimating its therapeutic efficacy in distal ulcerative colitis: comparison of orally administered mesalamine and sulfasalazine. Inflamm Bowel Dis 2001 7 : 221 5.
-
(2001)
Inflamm Bowel Dis
, vol.7
, pp. 221-5
-
-
Naganuma, M.1
Iwao, Y.2
Ogata, H.3
-
29
-
-
35448939644
-
A prospective, blinded assessment of distal colonic mucosal concentrations of 5-ASA and NAC-5ASA in UC patients treated with either balsalazide (Colazal) or a pH-dependent mesalamine (Asacol)
-
DDW abstract S1358).
-
Kornbluth A, Cuffari C, George J, et al. A prospective, blinded assessment of distal colonic mucosal concentrations of 5-ASA and NAC-5ASA in UC patients treated with either balsalazide (Colazal) or a pH-dependent mesalamine (Asacol). Gastroenterology 2006 130 (Suppl. 2 A-209 (DDW abstract S1358).
-
(2006)
Gastroenterology
, vol.130
, Issue.2
-
-
Kornbluth, A.1
Cuffari, C.2
George, J.3
-
30
-
-
35448961207
-
-
Presented at: 11th Annual FDA Science Forum; April 27-28, Washington, DC.
-
Kwon H, Lionberger R, Yu LX, et al. Simulation of absorption of mesalamine from delayed release tablets (abstract C-17). Presented at: 11th Annual FDA Science Forum; April 27-28, 2005 Washington, DC.
-
(2005)
Simulation of Absorption of Mesalamine from Delayed Release Tablets (Abstract C-17).
-
-
Kwon, H.1
Lionberger, R.2
Yu, L.X.3
-
31
-
-
35448952185
-
-
Presented at: 11th Annual FDA Science Forum; April 27-28, Washington, DC.
-
Moore T, Gao Z, Westenberger BJ, et al. Dissolution testing of mesalamine delayed release tablets (abstract I-29). Presented at: 11th Annual FDA Science Forum; April 27-28, 2005 Washington, DC.
-
(2005)
Dissolution Testing of Mesalamine Delayed Release Tablets (Abstract I-29).
-
-
Moore, T.1
Gao, Z.2
Westenberger, B.J.3
-
32
-
-
0032801475
-
Inflammation does not decrease intraluminal pH in chronic inflammatory bowel disease
-
Ewe K, Schwartz S, Petersen S, Press AG. Inflammation does not decrease intraluminal pH in chronic inflammatory bowel disease. Dig Dis Sci 1999 44 : 1434 9.
-
(1999)
Dig Dis Sci
, vol.44
, pp. 1434-9
-
-
Ewe, K.1
Schwartz, S.2
Petersen, S.3
Press, A.G.4
-
34
-
-
35448958078
-
Gut pH and transit time in ulcerative colitis appear sufficient for complete dissolution of pH-dependent 5-ASA-containing capsules (abstract T34)
-
Nugent SG, Kumar D, Rampton DS, Yazaki E, Evans DF. Gut pH and transit time in ulcerative colitis appear sufficient for complete dissolution of pH-dependent 5-ASA-containing capsules (abstract T34). Gut 2000 46 (Suppl. 2 A9.
-
(2000)
Gut
, vol.46
, Issue.2
-
-
Nugent, S.G.1
Kumar, D.2
Rampton, D.S.3
Yazaki, E.4
Evans, D.F.5
-
35
-
-
0031817515
-
Gastrointestinal pH profiles in patients with inflammatory bowel disease
-
Press AG, Hauptmann IA, Hauptmann L, et al. Gastrointestinal pH profiles in patients with inflammatory bowel disease. Aliment Pharmacol Ther 1998 12 : 673 8.
-
(1998)
Aliment Pharmacol Ther
, vol.12
, pp. 673-8
-
-
Press, A.G.1
Hauptmann, I.A.2
Hauptmann, L.3
-
37
-
-
0024949034
-
PH-Profile and regional transit times of the normal gut measured by a radiotelemetry device
-
Fallingborg J, Christensen LA, Ingeman-Nielsen M, Jacobsen BA, Abildgaard K, Rasmussen HH. pH-Profile and regional transit times of the normal gut measured by a radiotelemetry device. Aliment Pharmacol Ther 1989 3 : 605 13.
-
(1989)
Aliment Pharmacol Ther
, vol.3
, pp. 605-13
-
-
Fallingborg, J.1
Christensen, L.A.2
Ingeman-Nielsen, M.3
Jacobsen, B.A.4
Abildgaard, K.5
Rasmussen, H.H.6
|