Role of the serum and glucocorticoid inducible kinase SGK1 in glucocorticoid stimulation of gastric acid secretion

Pflugers Archiv European Journal of Physiology

Volumn 455, Issue 3, 2007, Pages 493-503

  Sandu, Ciprian ^a   Artunc, Ferruh ^a   Grahammer, Florian ^a   Rotte, Anand ^a   Boini, Krishna M ^a   Friedrich, Björn ^a   Sandulache, Diana ^a   Metzger, Marco ^a   Just, Lothar ^a   MacK, Andreas ^a   Skutella, Thomas ^a   Rexhepaj, Rexhep ^a   Risler, Teut ^a   Wulff, Peer ^b   Kuhl, Dietmar ^c   Lang, Florian ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Glucocorticoids; H+ secretion; K+ channels; Stomach

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM); CARBACHOL; CYCLIC AMP; DEXAMETHASONE; FORSKOLIN; GLUCOCORTICOID; OMEPRAZOLE; POTASSIUM CHANNEL; POTASSIUM CHANNEL KCNQ1; POTASSIUM ION; PROTON PUMP INHIBITOR; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; SODIUM ION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE TARGETING; GENETIC TRANSCRIPTION; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MOUSE; NONHUMAN; PEPTIC ULCER; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; STOMACH ACID SECRETION; STOMACH GLAND;

ANIMALS; CARBACHOL; CORTICOSTERONE; DEXAMETHASONE; FORSKOLIN; GASTRIC ACID; HYDROGEN-ION CONCENTRATION; IMMEDIATE-EARLY PROTEINS; KCNQ1 POTASSIUM CHANNEL; MICE; PARIETAL CELLS, GASTRIC; PROTEIN-SERINE-THREONINE KINASES;

EID: 35448956542     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-007-0305-4     Document Type: Article

References (59)

1. Abriel H, Kamynina E, Horisberger JD, Staub O (2000) Regulation of the cardiac voltage-gated Na+ channel (H1) by the ubiquitin-protein ligase Nedd4. FEBS Lett 466:377-380
2. Ahamed RN, Mummigatti UG, Samuel CS (1983) Effect of adrenalectomy and administration of prednisolone on gastric ulcer formation in forestomachectomized Shay albino rats. Indian J Physiol Pharmacol 27:298-304
3. Alessi DR, Andjelkovic M, Caudwell B, Cron P, Morrice N, Cohen P, Hemmings BA (1996) Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J 15:6541-6551
4. Alessi DR, Cohen P (1998) Mechanism of activation and function of protein kinase B. Curr Opin Genet Dev 8:55-62
5. Alliston TN, Gonzalez-Robayna IJ, Buse P, Firestone GL, Richards JS (2000) Expression and localization of serum/glucocorticoid-induced kinase in the rat ovary: relation to follicular growth and differentiation. Endocrinology 141:385-395
6. Alliston TN, Maiyar AC, Buse P, Firestone GL, Richards JS (1997) Follicle stimulating hormone-regulated expression of serum/glucocorticoid-inducible kinase in rat ovarian granulosa cells: a functional role for the Sp1 family in promoter activity. Mol Endocrinol 11:1934-1949
7. Alvarez de la Rosa D, Zhang P, Naray-Fejes-Toth A, Fejes-Toth G, Canessa CM (1999) The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytes. J Biol Chem 274:37834-37839
8. Bandyopadhyay U, Biswas K, Bandyopadhyay D, Ganguly CK, Banerjee RK (1999) Dexamethasone makes the gastric mucosa susceptible to ulceration by inhibiting prostaglandin synthetase and peroxidase-two important gastroprotective enzymes. Mol Cell Biochem 202:31-36
9. Barriga C, Martin MI, Tabla R, Ortega E, Rodriguez AB (2001) Circadian rhythm of melatonin, corticosterone and phagocytosis: effect of stress. J Pineal Res 30:180-187
10. Böhmer C, Wagner CA, Beck S, Moschen I, Melzig J, Werner A, Lin JT, Lang F, Wehner F (2000) The shrinkage-activated Na(+) conductance of rat hepatocytes and its possible correlation to rENaC. Cell Physiol Biochem 10:187-194
11. -. Am J Physiol 255:C844-C856
12. Busjahn A, Seebohm G, Maier G, Toliat MR, Nurnberg P, Aydin A, Luft FC, Lang F (2004) Association of the serum and glucocorticoid regulated kinase (sgk1) gene with QT interval. Cell Physiol Biochem 14:135-142
13. Chen SY, Bhargava A, Mastroberardino L, Meijer OC, Wang J, Buse P, Firestone GL, Verrey F, Pearce D (1999) Epithelial sodium channel regulated by aldosterone-induced protein sgk. Proc Natl Acad Sci USA 96:2514-2519
14. Cooke AR, Preshaw RM, Grossman ML (1966) Effect of adrenalectomy and glucocorticoids on the secretion and absorption of hydrogen ion. Gastroenterology 50:761-767
15. Debonneville C, Flores SY, Kamynina E, Plant PJ, Tauxe C, Thomas MA, Munster C, Chraibi A, Pratt JH, Horisberger JD, Pearce D, Loffing J, Staub O (2001) Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression. EMBO J 20:7052-7059
16. Dieter M, Palmada M, Rajamanickam J, Aydin A, Busjahn A, Boehmer C, Luft FC, Lang F (2004) Regulation of glucose transporter SGLT1 by ubiquitin ligase Nedd4-2 and kinases SGK1, SGK3, and PKB. Obes Res 12:862-870
17. Divecha N, Banfic H, Irvine RF (1991) The polyphosphoinositide cycle exists in the nuclei of Swiss 3T3 cells under the control of a receptor (for IGF-I) in the plasma membrane, and stimulation of the cycle increases nuclear diacylglycerol and apparently induces translocation of protein kinase C to the nucleus. EMBO J 10:3207-3214
18. Embark HM, Bohmer C, Vallon V, Luft F, Lang F (2003) Regulation of KCNE1-dependent K(+) current by the serum and glucocorticoid-inducible kinase (SGK) isoforms. Pflugers Arch 445:601-606
19. Firestone GL, Giampaolo JR, O'Keeffe BA (2003) Stimulus-dependent regulation of serum and glucocorticoid inducible protein kinase (SGK) transcription, subcellular localization and enzymatic activity. Cell Physiol Biochem 13:1-12
20. Gamper N, Fillon S, Feng Y, Friedrich B, Lang PA, Henke G, Huber SM, Kobayashi T, Cohen P, Lang F (2002) K(+) channel activation by all three isoforms of serum- and glucocorticoid-dependent protein kinase SGK. Pflugers Arch 445:60-66
21. - by stimulating three acid-base transport systems. Nature 337:648-651
22. Gonzalez-Robayna IJ, Falender AE, Ochsner S, Firestone GL, Richards JS (2000) Follicle-Stimulating hormone (FSH) stimulates phosphorylation and activation of protein kinase B (PKB/Akt) and serum and glucocorticoid-induced kinase (Sgk): evidence for A kinase-independent signaling by FSH in granulosa cells. Mol Endocrinol 14:1283-1300
23. Grahammer F, Henke G, Sandu C, Rexhepaj R, Hussain A, Friedrich B, Risler T, Metzger M, Just L, Skutella T, Wulff P, Kuhl D, Lang F (2006) Intestinal function of gene-targeted mice lacking serum- and glucocorticoid-inducible kinase 1. Am J Physiol Gastrointest Liver Physiol 290:G1114-G1123
24. Grahammer F, Herling AW, Lang HJ, Schmitt-Graff A, Wittekindt OH, Nitschke R, Bleich M, Barhanin J, Warth R (2001) The cardiac K+ channel KCNQ1 is essential for gastric acid secretion. Gastroenterology 120:1363-1371
25. Henke G, Setiawan I, Bohmer C, Lang F (2002) Activation of Na(+)/K(+)-ATPase by the Serum and Glucocorticoid-Dependent Kinase Isoforms. Kidney Blood Press Res 25:370-374
26. Hills CE, Bland R, Bennett J, Ronco PM, Squires PE (2006) High glucose up-regulates ENaC and SGK1 expression in HCD-cells. Cell Physiol Biochem 18:337-346
27. Huang DY, Wulff P, Volkl H, Loffing J, Richter K, Kuhl D, Lang F, Vallon V (2004) Impaired regulation of renal K+ elimination in the sgk1-knockout mouse. J Am Soc Nephrol 15:885-891
28. Kobayashi T, Cohen P (1999) Activation of serum- and glucocorticoid- regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2. Biochem J 339:319-328
29. Kobayashi T, Deak M, Morrice N, Cohen P (1999) Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase. Biochem J 344:189-197
30. Kotani K, Yonezawa K, Hara K, Ueda H, Kitamura Y, Sakaue H, Ando A, Chavanieu A, Calas B, Grigorescu F (1994) Involvement of phosphoinositide 3-kinase in insulin- or IGF-1-induced membrane ruffling. EMBO J 13:2313-2321
31. Lang F, Bohmer C, Palmada M, Seebohm G, Strutz-Seebohm N, Vallon V (2006) (Patho)physiological significance of the serum- and glucocorticoid-inducible kinase isoforms. Physiol Rev 86:1151-1178
32. Lang F, Cohen P (2001) Regulation and physiological roles of serum- and glucocorticoid-induced protein kinase isoforms. Sci STKE 2001:RE17
33. Lang F, Henke G, Embark HM, Waldegger S, Palmada M, Bohmer C, Vallon V (2003) Regulation of channels by the serum and glucocorticoid-inducible kinase-implications for transport, excitability and cell proliferation. Cell Physiol Biochem 13:41-50
34. Lang F, Klingel K, Wagner CA, Stegen C, Warntges S, Friedrich B, Lanzendorfer M, Melzig J, Moschen I, Steuer S, Waldegger S, Sauter M, Paulmichl M, Gerke V, Risler T, Gamba G, Capasso G, Kandolf R, Hebert SC, Massry SG, Broer S (2000) Deranged transcriptional regulation of cell-volume-sensitive kinase hSGK in diabetic nephropathy. Proc Natl Acad Sci USA 97:8157-8162
35. Lee MP, Ravenel JD, Hu RJ, Lustig LR, Tomaselli G, Berger RD, Brandenburg SA, Litzi TJ, Bunton TE, Limb C, Francis H, Gorelikow M, Gu H, Washington K, Argani P, Goldenring JR, Coffey RJ, Feinberg AP (2000) Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice. J Clin Invest 106:1447-1455
36. Loffing J, Zecevic M, Feraille E, Kaissling B, Asher C, Rossier BC, Firestone GL, Pearce D, Verrey F (2001) Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: possible role of SGK. Am J Physiol Renal Physiol 280:F675-F682
37. Maier G, Palmada M, Rajamanickam J, Shumilina E, Bohmer C, Lang F (2006) Upregulation of HERG channels by the serum and glucocorticoid inducible kinase isoform SGK3. Cell Physiol Biochem 18:177-186
38. Naray-Fejes-Toth A, Canessa C, Cleaveland ES, Aldrich G, Fejes-Toth G (1999) Sgk is an aldosterone-induced kinase in the renal collecting duct. Effects on epithelial Na+ channels. J Biol Chem 274:16973-16978
39. Nobuhara Y, Ueki S, Takeuchi K (1985) Influence of prednisolone on gastric alkaline response in rat stomach. A possible explanation for steroid-induced gastric lesion. Dig Dis Sci 30:1166-1173
40. Palmada M, Poppendieck S, Embark HM, van de Graaf SF, Boehmer C, Bindels RJ, Lang F (2005) Requirement of PDZ domains for the stimulation of the epithelial Ca2+ channel TRPV5 by the NHE regulating factor NHERF2 and the serum and glucocorticoid inducible kinase SGK1. Cell Physiol Biochem 15:175-182
41. Park J, Leong ML, Buse P, Maiyar AC, Firestone GL, Hemmings BA (1999) Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway. EMBO J 18:3024-3033
42. Raptis S, von Berger L, Dollinger HC, Fazekas AA, Pfeiffer EF (1976) Hypergastrinemia induced by glucocorticoid and corticotropin treatment in man. Am J Dig Dis 21:376-380
43. Richards JS, Fitzpatrick SL, Clemens JW, Morris JK, Alliston T, Sirois J (1995) Ovarian cell differentiation: a cascade of multiple hormones, cellular signals, and regulated genes. Recent Prog Horm Res 50:223-254
44. Roos A, Boron WF (1981) Intracellular pH. Physiol Rev 61:296-434
45. Seebohm G, Strutz-Seebohm N, Baltaev R, Korniychuk G, Knirsch M, Engel J, Lang F (2005) Regulation of KCNQ4 potassium channel prepulse dependence and current amplitude by SGK1 in Xenopus oocytes. Cell Physiol Biochem 16:255-262
46. Seebohm G, Strutz-Seebohm N, Birkin R, Dell G, Bucci C, Spinosa MR, Baltaev R, Mack AF, Korniychuk G, Choudhury A, Marks D, Pagano RE, Attali B, Pfeufer A, Kass RS, Sanguinetti MC, Tavare JM, Lang F (2007) Regulation of endocytic recycling of KCNQ1/KCNE1 potassium channels. Circ Res 100:686-692
47. Setiawan I, Henke G, Feng Y, Bohmer C, Vasilets LA, Schwarz W, Lang F (2002) Stimulation of Xenopus oocyte Na(+),K(+)ATPase by the serum and glucocorticoid-dependent kinase sgk1. Pflugers Arch 444:426-431
48. Shigaev A, Asher C, Latter H, Garty H, Reuveny E (2000) Regulation of sgk by aldosterone and its effects on the epithelial Na(+) channel. Am J Physiol Renal Physiol 278:F613-F619
49. Snyder PM, Olson DR, Thomas BC (2002) Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel. J Biol Chem 277:5-8
50. Vallon V, Grahammer F, Volkl H, Sandu CD, Richter K, Rexhepaj R, Gerlach U, Rong Q, Pfeifer K, Lang F (2005) KCNQ1-dependent transport in renal and gastrointestinal epithelia. Proc Natl Acad Sci USA 102:17864-17869
51. Verrey F, Loffing J, Zecevic M, Heitzmann D, Staub O (2003) SGK1: aldosterone-induced relay of Na+ transport regulation in distal kidney nephron cells. Cell Physiol Biochem 13:021-028
52. Wagner CA, Ott M, Klingel K, Beck S, Melzig J, Friedrich B, Wild KN, Broer S, Moschen I, Albers A, Waldegger S, Tummler B, Egan ME, Geibel JP, Kandolf R, Lang F (2001) Effects of the serine/threonine kinase SGK1 on the epithelial Na(+) channel (ENaC) and CFTR: implications for cystic fibrosis. Cell Physiol Biochem 11:209-218
53. Waldegger S, Barth P, Raber G, Lang F (1997) Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume. Proc Natl Acad Sci USA 94:4440-4445
54. Waldegger S, Klingel K, Barth P, Sauter M, Rfer ML, Kandolf R, Lang F (1999) h-sgk serine-threonine protein kinase gene as transcriptional target of transforming growth factor beta in human intestine. Gastroenterology 116:1081-1088
55. Wulff P, Vallon V, Huang DY, Volkl H, Yu F, Richter K, Jansen M, Schlunz M, Klingel K, Loffing J, Kauselmann G, Bosl MR, Lang F, Kuhl D (2002) Impaired renal Na(+) retention in the sgk1-knockout mouse. J Clin Invest 110:1263-1268
56. Yun CC, Chen Y, Lang F (2002) Glucocorticoid activation of Na(+)/H(+) exchanger isoform 3 revisited. The roles of SGK1 and NHERF2. J Biol Chem 277:7676-7683
57. Yun CC, Palmada M, Embark HM, Fedorenko O, Feng Y, Henke G, Setiawan I, Boehmer C, Weinman EJ, Sandrasagra S, Korbmacher C, Cohen P, Pearce D, Lang F (2002) The serum and glucocorticoid-inducible kinase SGK1 and the Na(+)/H(+) exchange regulating factor NHERF2 synergize to stimulate the renal outer medullary K(+) channel ROMK1. J Am Soc Nephrol 13:2823-2830
58. Zamora CS, Kowalczyk T, Hoekstra WG, Grummer RH, Will JA (1975) Effects of prednisone on gastric secretion and development of stomach lesions in swine. Am J Vet Res 36:33-39
59. Zecevic M, Heitzmann D, Camargo SM, Verrey F (2004) SGK1 increases Na,K-ATP cell-surface expression and function in Xenopus laevis oocytes. Pflugers Arch 448:29-35