Regulated expression of microRNAs in normal and polycythemia vera erythropoiesis

Experimental Hematology

Volumn 35, Issue 11, 2007, Pages 1657-1667

  Bruchova, Hana ^a,b   Yoon, Donghoon ^a   Agarwal, Archana M ^a   Mendell, Joshua ^c   Prchal, Josef T ^a,b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b INSTITUTE OF HEMATOLOGY AND BLOOD TRANSFUSION   (Czech Republic)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA;

ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ERYTHROPOIESIS; GENE EXPRESSION; HEMATOPOIESIS; HUMAN; HUMAN CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; POLYCYTHEMIA VERA; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; UPREGULATION;

CASE-CONTROL STUDIES; CELL DIFFERENTIATION; CELLS, CULTURED; ERYTHROID PROGENITOR CELLS; ERYTHROPOIESIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LEUKOCYTES, MONONUCLEAR; MICRORNAS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYCYTHEMIA VERA; TIME FACTORS;

EID: 35448950792     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2007.08.021     Document Type: Article

References (31)

1. Bellucci S., and Michiels J.J. The role of JAK2 V617F mutation, spontaneous erythropoiesis and megakaryocytopoiesis, hypersensitive platelets, activated leukocytes, and endothelial cells in the etiology of thrombotic manifestations in polycythemia vera and essential thrombocythemia. Semin Thromb Hemost 32 (2006) 381-398
2. Levine R.L., and Gilliland D.G. JAK-2 mutations and their relevance to myeloproliferative disease. Curr Opin Hematol 14 (2007) 43-47
3. Rumi E., Passamonti F., Pietra D., et al. JAK2 (V617F) as an acquired somatic mutation and a secondary genetic event associated with disease progression in familial myeloproliferative disorders. Cancer 107 (2006) 2206-2211
4. Lippert E., Boissinot M., Kralovics R., et al. The JAK2-V617F mutation is frequently present at diagnosis in patients with essential thrombocythemia and polycythemia vera. Blood 108 (2006) 1865-1867
5. Nussenzveig R.H., Swierczek S.I., Jelinek J., et al. Polycythemia vera is not initiated by JAK2V617F mutation. Exp Hematol 35 (2007) 32-38
6. Zhao Y., and Srivastava D. A developmental view of microRNA function. Trends Biochem Sci 32 (2007) 189-197
7. Garzon R., Pichiorri F., Palumbo T., et al. MicroRNA fingerprints during human megakaryocytopoiesis. Proc Natl Acad Sci U S A 103 (2006) 5078-5083
8. Georgantas III R.W., Hildreth R., Morisot S., et al. CD34+ hematopoietic stem-progenitor cell microRNA expression and function: a circuit diagram of differentiation control. Proc Natl Acad Sci U S A 104 (2007) 2750-2755
9. Neilson J.R., Zheng G.X., Burge C.B., and Sharp P.A. Dynamic regulation of miRNA expression in ordered stages of cellular development. Genes Dev 21 (2007) 578-589
10. Felli N., Fontana L., Pelosi E., et al. MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation. Proc Natl Acad Sci U S A 102 (2005) 18081-18086
11. Choong M.L., Yang H.H., and McNiece I. MicroRNA expression profiling during human cord blood-derived CD34 cell erythropoiesis. Exp Hematol 35 (2007) 551-564
12. Liu E., Jelinek J., Pastore Y.D., Guan Y., Prchal J.F., and Prchal J.T. Discrimination of polycythemias and thrombocytoses by novel, simple, accurate clonality assays and comparison with PRV-1 expression and BFU-E response to erythropoietin. Blood 101 (2003) 3294-3301
13. Gaikwad A., Nussenzveig R., Liu E., Gottshalk S., Chang K., and Prchal J.T. In vitro expansion of erythroid progenitors from polycythemia vera patients leads to decrease in JAK2 V617F allele. Exp Hematol 35 (2007) 587-595
14. Prchal J.T., Cashman D.P., and Kan Y.W. Hb Long Island [(β-l) Met; β 2(NA2)His→Pro] is caused by a single mutation (A to C) resulting in a failure to cleave N-terminal methionine. Proc Natl Acad Sci U S A 83 (1986) 24-28
15. Yoon D., Bruchova H., Agarwal A.M., Prchal J.T., and Prchal J.F. In vitro erythroid cell expansion analysis in polycythemia vera. [abstract]. Blood 108 11 (2006) 316b Abstract 4916
16. Thomson J.M., Parker J., Perou C.M., and Hammond S.M. A custom microarray platform for analysis of microRNA gene expression. Nat Methods 1 (2004) 47-53
17. Neildez-Nguyen T.M., Wajcman H., Marden M.C., et al. Human erythroid cells produced ex vivo at large scale differentiate into red blood cells in vivo. Nat Biotechnol 20 (2002) 467-472
18. Zhou B., Wang S., Mayr C., Bartel D.P., and Lodish H.F. miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely. Proc Natl Acad Sci U S A 104 (2007) 7080-7085
19. Rathjen T., Nicol C., McConkey G., and Dalmay T. Analysis of short RNAs in the malaria parasite and its red blood cell host. FEBS Lett 580 (2006) 5185-5188
20. Ramkissoon S.H., Mainwaring L.A., Ogasawara Y., et al. Hematopoietic-specific microRNA expression in human cells. Leuk Res 30 (2006) 643-647
21. Yu J., Wang F., Yang G.H., et al. Human microRNA clusters: genomic organization and expression profile in leukemia cell lines. Biochem Biophys Res Commun 349 (2006) 59-68
22. Calin G.A., Dumitru C.D., Shimizu M., et al. Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A 99 (2002) 15524-15529
23. Cimmino A., Calin G.A., Fabbri M., et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci U S A 102 (2005) 13944-13949
24. Testa U. Apoptotic mechanisms in the control of erythropoiesis. Leukemia 18 (2004) 1176-1199
25. Zermati Y., Garrido C., Amsellem S., et al. Caspase activation is required for terminal erythroid differentiation. J Exp Med 193 (2001) 247-254
26. Eis P.S., Tam W., Sun L., et al. Accumulation of miR-155 and BIC RNA in human B cell lymphomas. Proc Natl Acad Sci U S A 102 (2005) 3627-3632
27. Iorio M.V., Ferracin M., Liu C.G., et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res 65 (2005) 7065-7070
28. Scicchitano M.S., McFarland D.C., Tierney L.A., Narayanan P.K., and Schwartz L.W. In vitro expansion of human cord blood CD36+ erythroid progenitors: temporal changes in gene and protein expression. Exp Hematol 31 (2003) 760-769
29. Roldo C., Missiaglia E., Hagan J.P., et al. MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior. J Clin Oncol 24 (2006) 4677-4684
30. Detmer K., and Walker A.N. Bone morphogenetic proteins act synergistically with haematopoietic cytokines in the differentiation of haematopoietic progenitors. Cytokine 17 (2002) 36-42
31. Vegiopoulos A., Garcia P., Emambokus N., and Frampton J. Coordination of erythropoiesis by the transcription factor c-Myb. Blood 107 (2006) 4703-4710