Inclusion of biomarkers for detecting perturbations in the heart and lung and lipid/carbohydrate metabolism in National Toxicology Program Studies

Toxicological Sciences

Volumn 100, Issue 1, 2007, Pages 29-35

  Dunnick, June K ^a   Thayer, Kristina A ^a   Travlos, Gregory S ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Biomarkers; Cardiovascular system; Lipids

Indexed keywords

ALPHA 2 MACROGLOBULIN; BIOLOGICAL MARKER; BRAIN NATRIURETIC PEPTIDE; CHEMOKINE; CHOLESTEROL; FRUCTOSAMINE; INSULIN; TRIACYLGLYCEROL; TROPONIN;

ARTICLE; BIOASSAY; CARBOHYDRATE METABOLISM; CHOLESTEROL BLOOD LEVEL; DIAGNOSTIC IMAGING; DISEASE MARKER; GENETIC ANALYSIS; HEART DISEASE; HEART FUNCTION; HEART MUSCLE INJURY; HISTOPATHOLOGY; HUMAN; INFLAMMATION; LIPID METABOLISM; LUNG DISEASE; LUNG FUNCTION; LUNG LAVAGE; METABOLIC DISORDER; NONHUMAN; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; BIOLOGICAL ASSAY; BIOLOGICAL MARKERS; CARBOHYDRATE METABOLISM; GUIDELINES AS TOPIC; HEART; HEART INJURIES; HUMANS; LIPID METABOLISM; LUNG; MYOCARDIUM; PROGRAM DEVELOPMENT; RISK ASSESSMENT; TOXICITY TESTS; TOXICOLOGY; UNITED STATES;

RODENTIA;

EID: 35448935283     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm113     Document Type: Article

References (38)

1. Apple, F. S., Panteghini, M., Ravkilde, J., Mair, J., Wu, A. H. B., Tate, J., Pagani, F., Christenson, R. H., Jaffe, A. S., and Committee on standardization of markers of cardiac damage of the IFCC (2005a). Quality specifications for B-type natriuretic peptide assays. Clin. Chem. 51, 486-493.
2. Apple, F. S., Wu, A. H. B., Mair, J., Ravkilde, J., Panteghini, M., Tate, J., Pagani, F., Christenson, R. H., Mockel, M., Danne, O., et al. (2005b). Future biomarkers for detection of ischemia and risk stratification in acute coronary syndrome. Clin. Chem. 51, 810-824.
3. Badea, C., Hedlung, L. W., and Johnson, G. A. (2004). Micro-CT with respiratory and cardiac gating. Med. Phys. 31, 3324-3329.
4. Badea, C. T., Bucholz, E., Hedlund, L. W., Rockman, H. A., and Johnson, G. A. (2006). Imaging methods for morphological and functional phenotyping of the rodent heart. Toxicol. Path. 34, 111-117.
5. Badea, C. T., Fuhara, B., Hedlund, L. W., and Johnson, G. A. (2005). 4-D Micro-CT of the mouse heart. Mol. Imaging 4, 110-116.
6. Bakker, M. E., Stolk, J., Putter, H., Shaker, S. B., Parr, D. G., Piitulainen, E., Russi, E. W., Dirksen, A., Stockley, R. A., Reiber, J. H., et al. (2005). Variability in densitometric assessment of pulmonary emphysema with computed tomography. Invest. Radiol. 40, 777-783.
7. Benson, J. M., Burt, D. G., Cheng, Y. S., Hahn, F. F., Haley, P. J., Henderson, R. F., Hobbs, C. H., Pickrell, J. A., and Dunnick, J. K. (1989). Biochemical responses of rat and mouse lung to inhaled nickel compounds. Toxicology 57, 255-266.
8. Bishop, J. B., Tani, Y., Witt, K., Johnson, J. A., Peddada, S., Dunnick, J. K., and Nyska, A. (2004). Mitochondria damage revealed by morphometric and semiquantitive analysis of mouse pup cardiomyocytes following in utero and postnatal exposure to zidovudine and lamivudine. Toxicol. Sci. 81, 512-517.
9. Blaxall, B. C., Spang, R., Rockman, H. A., and Koch, W. J. (2003). Differential myocardial gene expression in the development and rescue of murine heart failure. Physiol. Genomics 15, 105-114.
10. Charo, I. F., and Ransohoff, R. M. (2006). The many roles of chemokines and chemokine receptors in inflammation. N. Engl. J. Med. 354 610-621.
11. Chen, X. J., Hedlund, L. W., Moller, H. E., Chawla, M. S., Maronpot, R. R., and Johnson, G. A. (2000). Detection of emphysema in rat lungs by using magnetic resonance measurements of He diffusion. Proc. Natl. Acad. Sci. U.S.A. 97, 11478-11481.
12. De Gruttola, V. G., Clax, P., DeMets, D. L., Downing, G. J., Ellenberg, S. S., Friedman, L., Gail, M. H., Prentice, R., Wittes, J., and Zeger, S. L. (2001). Considerations in the evaluation of surrogate endpoints in clinical trials: Summary of a National Institutes of Health workshop. Control. Clin. Trials 22, 485-502.
13. Dunnick, J., Johnson, J., Horton, J., and Nyska, A. (2004). Bis(2-chloroethoxy)-methane-induced mitochondrial and myofibrillar damage: Short-term time-course study. Toxicol. Sci. 81, 243-252.
14. Eckel, R. H., Grundy, S. M., and Zimmet, P. Z. (2005). The metabolic syndrome. Lancet 365, 1415-1428.
15. Florez, J. C., Jablonski, K. A., Bayley, N., Pollin, T. I., de Bakker, P. I. W., Shuldiner, A. R., Knowler, W. C., Nathan, D. M., Altshuler, D., and Diabetes Prevention Program Research Group (2006). TCF7L2 polymorphisms and progression to diabetes in the diabetes prevention program. N. Engl. J. Med. 355, 241-250.
16. Fonseca, V., Rosenstock, J., Patwardham, R., and Salzman, A. (2000). Effect of metformin and rosiglitazone combination therapy in pateints with type 2 diabetes mellitus. JAMA 283, 1695-1702.
17. Goodsaid, F., and Frueh, F. (2006). Process map proposal for the validation of genomic biomarkers. Future Med. 7, 773-782.
18. Henderson, R. F. (2005). Use of bronchoalveolar lavage to detect respiratory tract toxicity of inhaled material. Exp. Toxicol. Pathol. 57, 155-159.
19. Howden, R., Hanlon, P. R., Petranka, J. G., Kleeberger, S., Bucher, J., Dunnick, J., Nyska, A., and Murphy, E. (2005). Ephedrine plus caffeine causes age-dependent cardiovascular responses in Fischer 344 rats. Am. J. Physiol. Heart Circ. Physiol. 288, H2219-H2224.
20. Jaffe, A. S., Babuin, L., and Apple, F. S. (2006). Biomarkers in acute cardiac disease. J. Am. Coll. Cardiol. 48, 1-11.
21. Jamieson, J. A., Taylor, C. G., and Weiler, H. A. (2006). Marginal zinc deficiency exacerbates bone lead accumulation and high dietary zinc attenuates lead accumulation at the expense of bone density in growing rats. Toxicol. Sci. 92, 286-294.
22. Kraemer, H. C. (1992). Evaluating Medical Tests: Objective and Quantitative Guidelines. Sage Publications, London, England.
23. Lehmann, R., Bhargava, A. S., and Gunzel, P. (1993). Serum lipoprotein pattern in rats, dogs, and monkeys, including method comparison and influence of menstrual cycle in monkeys. Eur. J. Clin. Chem. Clin. Biochem. 31, 633-637.
24. Lubien, E., DeMaria, A., Krishnaswamy, P., Clopton, P., Koon, J., Kazanegre, R., Gardetto, N., Wanner, E., and Maisel, A. S. (2002). Utility of B-natriuretic peptide in detecting diastolic dysfunction. Circulation 105, 595-602.
25. March, T. H., Bowen, L. E., Finch, G. L., Nikula, K. J., Wayne, B. J., and Hobbs, C. H. (2005). Effects of strain and treatment with inhaled all-trans-retenoic acid on cigarette smoke-induced pulmonary emphysema in mice COPD. J. Chronic Obstruct. Dis. 2, 289-302.
26. March, T. H., Wilder, J. A., Esparza, D. C., Cossey, P. Y., Blair, L. F., Herrera, L. K., McDonald, J. D., Campen, M. J., Mauderly, J. L., and Seagrave, J. C. (2006). Modulators of cigarette smoke-induced pulmonary emphysema in A/J mice. Toxicol. Sci. 92, 545-559.
27. McDonough, J. L., and Van Eyk, J. E. (2004). Developing the next generation of cardiac markers: Disease-induced modifications of troponin I. Prog. Cardiovasc. Dis. 47, 207-216.
28. Meert, A. P., Feoli, F., Martin, B., Verdebout, J. M., Mascaux, C., Verhest, A., Ninane, V., and Sculier, J. P. (2004). Ki67 expression in bronchial preneoplastic lesions and carcinoma in situ defined according to the new 1999 WHO/IASLC criteria: A preliminary study. Histopathology 44, 47-53.
29. Monnier, V. M. (2006). The fructosamine, 3-kinase knockout mouse: A tool for testing the glycation hypothesis of intracellular protein damage in diabetes and aging. Biochem. J. 399, e11-e13.
30. Muoio, D. M., and Newgard, C. B. (2006). Obesity-related derangements in metabolic regulation. Annu. Rev. Biochem. 75, 367-401.
31. Rendell, M., Stephen, P. M., Pauisen, R., Valentine, J. R., Rasbold, K., Hestorff, T., Eastberg, S., and Shin, D. C. (1985). An interspecies comparison of normal levels of glycosylated hemoglobin and glycosylated albumin. Comp. Biochem. Physiol. 81B, 819-822.
32. 1c. JAMA 295, 1688-1697.
33. Schwartz, D. A., Freedman, J. H., and Linney, E. A. (2004). Environmental genomics: A key to understanding biology, pathophysiology and disease. Hum. Mol. Genet. 13, R217-R224.
34. Seagrave, J. C., McDonald, J. D., Reed, M. D., Seilkop, S. K., and Mauderly, J. L. (2005). Responses to subchronic inhalation of low concentrations of diesel exhaust and hardwood smoke measured in rat bronchoalveolar lavage fluid. Inhal. Toxicol. 17, 657-670.
35. Wallace, K. B., Hausner, E., Herman, E., Holt, G. D., MacGregor, J. T., Metz, A. L., Murphy, E., Rosenblum, I. Y., Sistare, F. D., and York, M. J. (2004). Serum troponins as biomarkers of drug-induced cardiac toxicity. Toxicol. Pathol. 32, 106-121.
36. Weiss, R., Dziura, J., Burgett, T. S., Tamborlane, W. V., Taksali, S. E., Yeckel, C. W., Allen, K., Lopes, M., Savoye, M., Morrison, J., et al. (2004). Obesity and the metabolic syndrome in children and adolescents. N. Engl. J. Med. 350, 2362-2374.
37. Wesselkamper, S. C., Case, L. M., Henning, L. N., Borchers, M. T., Tichelaar, J. W., Mason, J. M., Dragin, N., Medvedovic, M., Sartor, M. A., Tomlinson, C. R., et al. (2005). Gene expression changes during the development of acute lung injury: Role of transforming growth factor beta. Am. J. Respir. Crit. Care. Med. 172, 1399-1411.
38. Zhang, J., Herman, E. N., Robertson, D. G., Roily, M. D., Knapton, A., Ratajczak, H., Rifal, N., Haonchel, R., Blanchard, K. T., Stoll, R., et al. (2006). Mechanisms and biomarkers of cardiovascular injury induced by phophodiesterase inhibitor III SK&F.95654 in the spontaneously hypertensive rat. Toxicol. Pathol. 34, 152-163.