메뉴 건너뛰기




Volumn 17, Issue 4 A, 1997, Pages 2385-2389

Induction of apoptotic cell death in three human osteosarcoma cell lines by a polyamine synthesis inhibitor, methylglyoxal bis (cyclopentylamidinohydrazone) (MGBCP)

Author keywords

DNA fragmentation; MGBCP; Osteosarcoma cells; Programmed cell death (apoptosis)

Indexed keywords

METHYLGLYOXAL; METHYLGLYOXAL BIS(CYCLOPENTYLAMIDINOHYDRAZONE); POLYAMINE; UNCLASSIFIED DRUG;

EID: 0030857589     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (17)

References (16)
  • 1
    • 0027238083 scopus 로고
    • Spermidine/spermine N1-acetyltransferase-the turning point in polyamine metabolism
    • Casero Jr R A and Pegg A E: Spermidine/spermine N1-acetyltransferase-the turning point in polyamine metabolism. FASEB J 7: 653-661, 1993.
    • (1993) FASEB J , vol.7 , pp. 653-661
    • Casero Jr., R.A.1    Pegg, A.E.2
  • 2
    • 0023881236 scopus 로고
    • Polyamine metabolism and its importance in neoplastic growth as target for chemotherapy
    • Pegg A E: Polyamine metabolism and its importance in neoplastic growth as target for chemotherapy. Cancer Res 48: 759-774, 1988.
    • (1988) Cancer Res , vol.48 , pp. 759-774
    • Pegg, A.E.1
  • 3
    • 0028851316 scopus 로고
    • Methylglyoxal bis(cyclopentylamidinohydrazone)(MGBCP): Antitumor effect against human osteosarcoma cells and combined effect with methotrexate, adriamycin and hydroperoxyifosfamide
    • Sonoda J, Hibasami H, Yamada H, Nakashima K and Ogihara Y: Methylglyoxal bis(cyclopentylamidinohydrazone)(MGBCP): antitumor effect against human osteosarcoma cells and combined effect with methotrexate, adriamycin and hydroperoxyifosfamide. Anticancer Res 15: 907-910, 1995.
    • (1995) Anticancer Res , vol.15 , pp. 907-910
    • Sonoda, J.1    Hibasami, H.2    Yamada, H.3    Nakashima, K.4    Ogihara, Y.5
  • 4
    • 0027881691 scopus 로고
    • Role of programmed cell death in carcinogenesis
    • Isaacs J T: Role of programmed cell death in carcinogenesis. Environ Health Perspect 101(suppl. 5): 27-34, 1993.
    • (1993) Environ Health Perspect , vol.101 , Issue.SUPPL. 5 , pp. 27-34
    • Isaacs, J.T.1
  • 5
    • 0026670335 scopus 로고
    • Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: An overview
    • Wyllie A H: Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: an overview. Cancer Metastasis Rev 11: 95- 103, 1992.
    • (1992) Cancer Metastasis Rev , vol.11 , pp. 95-103
    • Wyllie, A.H.1
  • 6
    • 0027217084 scopus 로고
    • Apoptotic death in epitherial cells: Cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation
    • Oberhammer F, Wilson JW, Dive C, Morris ID, Hickman JA, Wakeling AE, Walker PR and Sikorska M: Apoptotic death in epitherial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J 12: 3679-3684, 1993.
    • (1993) EMBO J , vol.12 , pp. 3679-3684
    • Oberhammer, F.1    Wilson, J.W.2    Dive, C.3    Morris, I.D.4    Hickman, J.A.5    Wakeling, A.E.6    Walker, P.R.7    Sikorska, M.8
  • 8
    • 0002861247 scopus 로고
    • Modulationof antineoplastic drug action by inhibitors of polyamine biosynthesis
    • McCann PP, Pegg AE and Sjoerdsma A (eds), New York, Academic Press
    • Porter C W and Janne J: Modulationof antineoplastic drug action by inhibitors of polyamine biosynthesis. In: McCann PP, Pegg AE and Sjoerdsma A (eds), Inhibition of Polyamine Metabolism: Biological Significance and Basis for New Therapies, New York, Academic Press, 1987, pp. 203-248.
    • (1987) Inhibition of Polyamine Metabolism: Biological Significance and Basis for New Therapies , pp. 203-248
    • Porter, C.W.1    Janne, J.2
  • 9
    • 0025823758 scopus 로고
    • Spermine prevents endonuclease activation and apoptosis in thymocytes
    • Brune B, Hartzell P, Nicotera P and Orrenius S: Spermine prevents endonuclease activation and apoptosis in thymocytes. Exp Cell Res 195: 323-329, 1991.
    • (1991) Exp Cell Res , vol.195 , pp. 323-329
    • Brune, B.1    Hartzell, P.2    Nicotera, P.3    Orrenius, S.4
  • 10
    • 0029769675 scopus 로고    scopus 로고
    • Induction of programmed cell death (apoptosis) in human lymphoid leukemia cells by catechin compounds
    • Hibasami H, Achiwa Y, Fujikawa T and Komiya T: Induction of programmed cell death (apoptosis) in human lymphoid leukemia cells by catechin compounds. Anticancer Res 11: 1943- 1946, 1996.
    • (1996) Anticancer Res , vol.11 , pp. 1943-1946
    • Hibasami, H.1    Achiwa, Y.2    Fujikawa, T.3    Komiya, T.4
  • 11
    • 0023632034 scopus 로고
    • Methylglyoxal bis(guanylhydrazone) analogs: Multifunctional inhibitors for polyamine enzymes
    • Nakashima K, Hibasami H, TsukadaTand Maekawa S: Methylglyoxal bis(guanylhydrazone) analogs: multifunctional inhibitors for polyamine enzymes. Eur J Med Chem 22: 553-558, 1987.
    • (1987) Eur J Med Chem , vol.22 , pp. 553-558
    • Nakashima, K.1    Hibasami, H.2    Tsukada, T.3    Maekawa, S.4
  • 12
    • 0028357173 scopus 로고
    • Rapid quantitation of apoptosis in pure and heterogeneous cell populations using flow cytometry
    • Telford WG, King LE and Fraker PJ: Rapid quantitation of apoptosis in pure and heterogeneous cell populations using flow cytometry. J Immunol Methods 172: 1-16, 1994.
    • (1994) J Immunol Methods , vol.172 , pp. 1-16
    • Telford, W.G.1    King, L.E.2    Fraker, P.J.3
  • 14
    • 0000163138 scopus 로고
    • Preparation of genomic DNA
    • Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
    • Maniatis T, Fritsch EF and Sambrook J: Preparation of genomic DNA. In: Molecular cloning, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, 1989, pp. 9.14.
    • (1989) Molecular Cloning , pp. 914
    • Maniatis, T.1    Fritsch, E.F.2    Sambrook, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.