Potential psychosocial mechanisms linking depression to immune function in elderly subjects

Psychiatry Research

Volumn 127, Issue 3, 2004, Pages 237-245

  Bouhuys, Antoinette L ^a   Flentge, Frans ^a   Oldehinkel, Albertine J ^a   Van Den Berg, Marjan D ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Cytokines; Depression; Elderly; Immunology; Personality; Social support

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 6;

ADULT; AGED; ARTICLE; CELL COUNT; CONTROLLED STUDY; DEPRESSION; EXTRAVERSION; FEMALE; GERIATRIC PATIENT; HUMAN; IMMUNE SYSTEM; LYMPHOCYTE; MAJOR CLINICAL STUDY; MALE; NATURAL KILLER CELL; NEUROSIS; PRIORITY JOURNAL; SOCIAL PSYCHOLOGY; SOCIAL SUPPORT; T LYMPHOCYTE;

AGED; AGED, 80 AND OVER; ANTIGENS, CD4; ANTIGENS, CD8; DEPRESSIVE DISORDER, MAJOR; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; EXTRAVERSION (PSYCHOLOGY); FEMALE; FLOW CYTOMETRY; HUMANS; INTERLEUKIN-6; KILLER CELLS, NATURAL; MALE; MIDDLE AGED; NEUROTIC DISORDERS; POPULATION SURVEILLANCE; PSYCHOLOGY; RISK FACTORS; SOCIAL SUPPORT;

EID: 3543101438     PISSN: 01651781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.psychres.2004.05.001     Document Type: Article

References (37)

1. American Psychiatric Association, 1994. Diagnostic and Statistical Manual of Mental Disorders (DSM IV), Washington, DC.
2. Al Windi A., Elmfeldt D., Tibblin G., Svardsudd K. The influence of sociodemographic characteristics on well-being and symptoms in a Swedish community. Results from a postal questionnaire survey. Scandinavian Journal of Primary Health Care. 17:1999;201-209
3. Angst J. Clinical course of affective disorders. Helgason T., Daly R.J. Depressive Illness: Prediction of Course and Outcome. 1988;144 Springer-Verlag, Berlin
4. Cohen F., Kearney K.A., Zegans L.S., Kemeny M.E., Neuhaus J.M., Stites D.P. Differential immune system changes with acute and persistent stress for optimists vs. pessimists. Brain, Behavior and Immunology. 13:1999;155-174
5. Coyne J.C., Aldwin C., Lazarus R.S. Depression and coping in stressful episodes. Journal of Abnormal Psychology. 90:(5):1981;439-447
6. Coyne J.C., Downey G. Social factors and psychopathology: stress, social support, and coping processes. Annual Review of Psychology. 42:1991;401-425
7. Dentino A.N., Pieper C.F., Rao M.K., Currie M.S., Harris T., Blazer D.G., Cohen H.J. Association of interleukin-6 and other biologic variables with depression in older people living in the community. Journal of the American Geriatrics Society. 47:1999;6-11
8. Duggan C.F., Sham P., Lee A., Minne C., Murray R. Neuroticism: a vulnerability marker for depression evidence from a family study. Journal of Affective Disorders. 35:1995;139-143
9. Eysenck H.J., Eysenck S.B.G. Manual of the Eysenck Personality Questionnaire. 1975;Hodder and Stoughton, London
10. Ferrucci L., Harris T.B., Guralnik J.M., Tracy R.P., Corti M.C., Cohen H.J., Penninx B., Pahor M., Wallace R., Havlik R.J. Serum IL-6 level and the development of disability in older persons. Journal of the American Geriatrics Society. 47:1999;639-646
11. Flentge, F., Bouhuys, A.L., van den Berg, M.D., Oldehinkel, A.J., Limburg, P.C., The, H.T., 2004. Immunological findings in aged depressives. Submitted
12. Flentge F., van den Berg M.D., Bouhuys A.L., The H.T. Increase of NK-T cells in aged depressed patients not treated with antidepressive drugs. Biological Psychiatry. 48:2000;1024-1027
13. Folkman S., Lazarus R.S. Stress processes and depressive symptomatology. Journal of Abnormal Psychology. 95:(2):1986;107-113
14. Herbert T., Cohen S. Depression and immunity: a meta-analytic review. Psychological Bulletin. 113:(3):1993;472-486
15. Ishihara S., Nohara R., Makita S., Imai M., Kubo S., Hashimoto T. Immune function and psychological factors in patients with coronary heart disease (I). Japanese Circulation Journal. 63:1999;704-709
16. Kamen-Siegel L., Rodin J., Seligman M.E., Dwyer J. Explanatory style and cell-mediated immunity in elderly men and women. Health Psychology. 10:1991;229-235
17. Kempen G.I.J.M., Van Eijk L.M. The psychometric properties of the SSL12-I, a short scale for measuring social support in the elderly. Social Indicators Research. 35:1995;303-312
18. Kiecolt-Glaser J.K., McGuire L., Robles T.F., Glaser R. Emotions, morbidity, and mortality: New Perspectives from Psychoneuroimmunology. Annual Review of Psychology. 53:2002;83-107
19. Kiecolt-Glaser J.K., McGuire L., Robles T.F., Glaser R. Psychoneuroimmunology and psychosomatic medicine: back to the future. Psychosomatic Medicine. 64:2002b;15-28
20. Kiecolt-Glaser J.K., McGuire L., Robles T.F., Glaser R. Psychoneuroimmunology: psychological influences on immune function and health. Journal of Consulting and Clinical Psychology. 70:2002c;537-547
21. Kronfol Z., Remick D.G. Cytokines and the brain: implications for clinical psychiatry. American Journal of Psychiatry. 157:2000;683-694
22. LaPerriere A., Ironson G., Antoni M.H., Schneiderman N., Klimas N., Fletcher M.A. Exercise and psychoneuroimmunology. Medicine and Science in Sports and Exercise. 1993;182-190
23. Lazarus R.S., Folkman S. Stress, Appraisal and Coping. 1984;Springer Publishing Company, New York
24. Lesher E.L., Berryhill J.S. Serum level monitoring of thiothixene in schizophrenia: acute single-dose levels at fixed doses. American Journal of Psychiatry. 139:1982;174-178
25. Lutgendorf S.K., Garand L., Buckwalter K.C., Reimer T.T., Hong S.Y., Lubaroff D.M. Life stress, mood disturbance, and elevated interleukin-6 in healthy older women. Journals of Gerontology, Series-A, Biological Sciences and Medical Sciences. 54:1999;M434-M439
26. Maier W., Lichtermann D., Minges J., Heun R. Personality traits in subjects at risk for unipolar major depression: a family study perspective. Journal of Affective Disorders. 24:1992;153-164
27. Miller A.H. Neuroendocrine and immune system interactions in stress and depression. Psychiatric Clinics of North America. 21:1998;443-463
28. Miller G.E., Cohen S., Rabin B.S., Skoner D.P., Doyle W.J. Personality and tonic cardiovascular, neuroendocrine, and immune parameters. Brain, Behavior and Immunology. 13:1999;109-123
29. Ormel J., Oldehinkel A.J., Brilman E.I. The interplay and etiological continuity of neuroticism, difficulties, and life events in the etiology of major and subsyndromal, first and recurrent depressive episodes in later life. American Journal of Psychiatry. 158:2001;885-891
30. Paykel E.S. Life events, social support and depression. Acta Psychiatrica Scandinavica. 89:1994;50-58
31. Segerstrom S.C. Personality and the immune system: models, methods and mechanisms. Annals of Behavioral Medicine. 22:2000;180-190
32. Uchino B.N., Cacioppo J.T., Malarkey W., Glaser R. The relationship between social support and physiological processes: a review with emphasis on underlying mechanisms and implications for health. Psychological Bulletin. 119:1996;488-531
33. Van den Berg M.D., Oldehinkel A.J., Brilman E.I., Bouhuys A.L., Ormel J.O. Correlates of symptomatic, minor and major depression in the elderly. Journal of Affective Disorders. 60:(2):2000;87-95
34. Wikby A., Maxson P., Olsson J., Johansson B., Ferguson F.G. Changes in CD8 and CD4 lymphocyte subsets, T cell proliferation responses and non-survival in the very old: the Swedish longitudinal OCTO-immune study. Mechanisms of Ageing and Development. 102:1998;187-198
35. Wikby A., Johansson B., Olsson J., Lofgren S., Nilsson B.O., Ferguson F. Expansions of peripheral blood CD8 T-lymphocyte subpopulations and an association with cytomegalovirus seropositivity in the elderly: the Swedish NONA immune study. Experimental Gerontology. 37:2002;445-453
36. Yesavage J.A. A revised version of the Psychoticism scale. Personality and Individual Differences. 6:1985;21-29
37. Zorrilla E.P., Luborsky L., McKay J.R., Rosenthal R., Houldin A., Tax A., McCorkle R., Seligman D.A., Schmidt K. The relationship of depression and stressors to immunological assays: a meta-analytic review. Brain, Behavior and Immunology. 15:2001;199-226