Protective effect of naringin, a bioflavonoid on ferric nitrilotriacetate-induced oxidative renal damage in rat kidney

Toxicology

Volumn 201, Issue 1-3, 2004, Pages 1-8

  Singh, Devinder ^a   Chander, Vikas ^a   Chopra, Kanwaljit ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

Naringin; Nitrilotriacetic acid; Oxidative stress

Indexed keywords

ANTIOXIDANT; AURANTIIN; BIOFLAVONOID; CATALASE; GLUTATHIONE REDUCTASE; NITRILOTRIACETATE IRON; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID DERIVATIVE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG EFFECT; INJECTION; KIDNEY FUNCTION; KIDNEY INJURY; MALE; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PREMEDICATION; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE;

ANIMALS; CHELATING AGENTS; CREATININE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVANONES; KIDNEY DISEASES; LIPID PEROXIDATION; MALE; NITRILOTRIACETIC ACID; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE;

ANIMALIA; RODENTIA;

EID: 3543099736     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2004.03.028     Document Type: Article

References (32)

1. Ameer B., Weintraub R.A., Johnson J.V., Yost R.A., Rouseff R.L. Flavanone absorption after naringin, hesperidin, and citrus administration. Clin. Pharmacol. Ther. 60:1996;34-40
2. Anderson R.L., Bishop W.E., Campbell R.L. A review of the environment and mammalian toxicology of nitrilotriacetic acid. Crit. Rev. Toxicol. 15:1985;1-102
3. Awai M., Narasaki M., Yamanoi Y., Seno S. Induction of diabetes in animals by parentral administration of ferric nitrilotriacetate. A model of experimental hemochromatosis. Am. J. Pathol. 95:1979;663-672
4. Carlberg I., Mannerviek B. Purification and characterization of the flavoenzyme glutathione reductase from rat liver. J. Biol. Chem. 250:1975;5475-5490
5. Chen Y.T., Zheng R.L., Jia Z.J., Ju Y. Flavonoids as superoxide scavengers and anti-oxidants. Free Radic. Biol. Med. 9:1990;19-21
6. Claiborne, A. 1985. In: R.A. Greenwald (Eds.), CRC Handbook of Methods for Oxygen Radical Reaserch, CRC Press, Boca Raton, Florida, USA. pp. 283-284.
7. Francis A.R., Shetty T.K., Bhattacharya R.K. Modulating effect of plant flavonoids on the mutagenicity of N-methyl-N′-nitro-N-nitrosoguanidine. Carcinogenesis. 10:1989;1953-1955
8. Hamazaki S., Okada S., Ebina Y., Fujioka M., Midorikawa O. Acute renal failure and glycosuria induced by ferric nitrilotriacetate in rats. Toxicol. Appl. Pharmacol. 77:1985;267-274
9. Hamazaki S., Okada S., Li J.L., Toyokuni S., Midorikoe O. Oxygen reduction and lipid peroxidation by iron chelates with special reference to ferric nitrilotriacetate. Arch. Biochem. Biophys. 272:1989;10-17
10. Jeon S.M., Bok S.H., Jang M.K., Lee M.K., Nam K.T., Park Y.B., Rhee S.J., Choi M.S. Antioxidative activity of naringin and lovastatin in high cholesterol-fed rabbits. Life Sci. 69:2001;2855-2866
11. Jollow D.J., Mitchell L.R., Zampaglione N., Gillete J.R. Bromobenze-induced liver necrosis: protective role of glutathione and evidence for 3,4-bromobenzeneoxide as the hepatotoxic intermediate. Pharmacology. 11:1974;151-169
12. Jung G., Hennings G., Pfeifer M., Bessler W.G. Interaction of metal-complexing compounds with lymphocytes and lymphoid cell lines. Mol. Pharmacol. 23:1983;698-702
13. Kanno S., Shouji A., Asou K., Ishikawa M. Effects of naringin on hydrogen peroxide-induced cytotoxicity and apoptosis in p388 cells. J. Pharmacol. Sci. 92:2003;166-170
14. Kono Y. Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase. Arch. Biochem. Biophys. 186:1978;189-195
15. Kroyer G. The anti-oxidant activity of citrus fruit peels. Z. Ernahrungswiss. 25:1986;63-69
16. Li J.L., Okada S., Hamazaki Y., Ebina O. Subacute nephrotoxicity and induction of renal cell carcinoma in mice treated with ferric nitrilotriacetate. Cancer Res. 47:1987;1867-1869
17. Liu M., Okada S., Kawabata T. Radical promoting free iron level in the serum of rats treated with ferric nitrilotriacetate, comparison with iron chelate complexes. Acta Med. Okayama. 45:1991;401-408
18. +-loss and lipid peroxidation induced by oxygen free radicals in human red cells. Pharmacol. Res. Commun. 18:1986;61-72
19. Mohandas J., Marshall J.J., Duggin G.G., Horvath J.S., Tiller D. Low activities of glutathione-related enzymes as factors in the genesis of urinary-bladder cancer. Cancer Res. 44:1984;5086-5091
20. Motilva V., Alarcon de la L.C., Martin M.J. Ulcer-protecting effects of naringenin on gastric lesions induced by ethanol in rat: role of endogenous prostaglandins. J. Pharm. Pharmacol. 46:1994;91-94
21. Nath A.K., Suzame M.N. Reactive oxygen species and acute renal failure. Am. J. Med. 109:2000;665-678
22. Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 95:1979;351-358
23. Okada S., Hamazaki S., Zhang D., Ma Y., 1988. Iron induced, free radical-mediated renal carcinogenesis in rats and mice: modification by sex and vitamin E. In: Packer L., Ong A.S.H. (Eds.), Biological Anti-Oxidants: Mechanism and Health Effects. AOCS Press, Champaign, IL, 1998, pp. 358-361.
24. Parmar N.S. The gastric anti-ulcer activity of naringenin, a specific histidine decarboxylase inhibitor. Int. J. Tissue React. 5:1983;415-420
25. Rojas D., Sanchez V.R., Somoza B., Ortega T., Villar A. Vasodilatory effect of naringenin in rat aorta. Phytother. Res. 10:1996;S123-S125
26. Salvi A., Carrupt P., Tillement J., Testa B. Structural damage to proteins caused by free radicals: asessment, protection by anti-oxidants, and influence of protein binding. Biochem. Pharmacol. 61:2001;1237-1242
27. So F.V., Guthrie N., Chambers A.F., Moussa M., Carroll K.K. Inhibition of human breast cancer cell proliferation and delay of mammary tumorigenesis by flavonoids and citrus juices. Nutr. Cancer. 26:1996;167-181
28. Toyokuni S. Iron-induced carcinogenesis: the role of redox regulation. Free Radic. Biol. Med. 20:1996;553-566
29. Toyokuni S., Uchida K., Okamoto K., Hattori-Nakakuki Y., Hiai H., Stadtman E.R. Formation of 4-hydroxy-2-nonenal-modified proteins in the renal proximal tubules of rats treated with a renal carcinogen, ferric nitrilotriacetate. Proc. Natl. Acad. Sci. USA. 91:1994;2616-2620
30. Umemura T.Y., Sai K., Takagi A., Hasegawa R., Kurokawa Y. Formation of 8-hydroxydeoxyguanosine (8-OH-dG) in rat kidney DNA after intra-peritoneal administration of ferric nitrilotriacetate (Fe-NTA). Carcinogenesis. 11:1990a;345-347
31. Umemura T.Y., Sai K., Takagi A., Hasegawa R., Kurokawa Y. Oxidative DNA damage, lipid peroxidation and nephrotoxicity induced in the rat kidney after ferric nitrilotriacetate administration. Cancer Lett. 54:1990b;95-100
32. Varley, H., 1988. In: Varley Harold (Ed.), Practical Clinical Biochemistry, CBS, Delhi.