The glycopeptide vancomycin does not enhance toll-like receptor 2 (TLR2) activation by Streptococcus pneumoniae

Journal of Antimicrobial Chemotherapy

Volumn 54, Issue 1, 2004, Pages 76-78

  Moore, Lisa J ^a   Pridmore, Alison C ^a   Dower, Steven K ^a   Read, Robert C ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Cefotaxime; Faropenem; Inflammation; Vancomycin

Indexed keywords

CEFOTAXIME; FROPENEM; GLYCOPEPTIDE; INTERLEUKIN 8; TOLL LIKE RECEPTOR 2; VANCOMYCIN;

ARTICLE; CELL STIMULATION; CONTROLLED STUDY; EXPRESSION VECTOR; GENE ACTIVATION; GENE ACTIVITY; GENETIC TRANSFECTION; GROWTH CURVE; HELA CELL; LUMINESCENCE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PLASMID; PROMOTER REGION; PROTEIN INDUCTION; REPORTER GENE; STREPTOCOCCUS PNEUMONIAE;

ANTI-BACTERIAL AGENTS; ANTIGENS, CD14; BETA-LACTAMS; CEFOTAXIME; CELL WALL; CEPHALOSPORINS; GENES, REPORTER; HELA CELLS; HUMANS; INTERLEUKIN-8; LACTAMS; LUCIFERASES; MEMBRANE GLYCOPROTEINS; MICROBIAL SENSITIVITY TESTS; PLASMIDS; RECEPTORS, CELL SURFACE; STREPTOCOCCUS PNEUMONIAE; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTORS; TRANSFECTION; VANCOMYCIN;

EID: 3543086259     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/dkh301     Document Type: Article

References (16)

1. British National Formulary (BNF) (March 2003). Notes on Drugs and Preparations. London
2. Yoshimura, A., Lien, E., Ingalls, R. R. et al. (1999). Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2. Journal of Immunology 163,1-5.
3. Moore, L. J., Pridmore, A. C., Dower, S. K. et al. (2003). Penicillin enhances toll-like receptor mediated proinflammatory activity of Streptococcus pneumoniae. Journal of Infectious Diseases 188, 1040-8.
4. Tuomanen, E., Liu, H., Hengstler, B. et al. (1985). The induction of meningeal inflammation by components of the pneumococcal cell wall. Journal of Infectious Diseases 151, 859-68.
5. Schwandner, R., Dziarski, R., Wesche, H. et al. (1999). Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2. Journal of Biological Chemistry 274, 17406-9.
6. Horii, T., Ichiyama, S., Ohta, M. et al. (1999). Relationship between morphological changes and endotoxin release induced by carbapenems in Pseudomonas aeruginosa. Journal of Medical Microbiology 48, 309-15.
7. Horne, D. & Tomasz, A. (1981). Hypersusceptibility of penicillin-treated group B streptococci to bactericidal activity of human polymorphonuclear leukocytes. Antimicrobial Agents and Chemotherapy 19, 745-53.
8. National Committee for Clinical Laboratory Standards (1997). Bacteria that Grow Aerobically; the Microbroth Dilution Method for Susceptibility Testing. NCCLS, Villanova, PA, USA.
9. Pridmore, A. C., Wyllie, D. H., Abdillahi, F. et al. (2001). A lipopolysaccharide-deficient mutant of Neisseria meningitidis elicits attenuated cytokine release by human macrophages and signals via toll-like receptor (TLR) 2 but not via TLR4/MD2. Journal of Infectious Diseases 183, 89-96.
10. Wyllie, D. H., Kiss-Toth, E., Visintin, A. et al. (2000). Evidence for an accessory protein function for Toll-like receptor 1 in anti-bacterial responses. Journal of Immunology 165, 7125-32.
11. Hakenbeck, R., Tornette, S. & Adkinson, N. F. (1987). Interaction of non-lytic β-lactams with penicillin-binding proteins in Streptococcus pneumoniae. Journal of General Microbiology 133, 755-60.
12. Dalhoff, A., Nasu, T. & Okamoto, K. (2003). Target affinities of faropenem to and its impact on the morphology of Gram-positive and Gram-negative bacteria. Chemotherapy 49, 172-83.
13. Tipper, D. J. (1987). Mode of action of β-lactam antibiotics. Antibiotic Inhibitors of Cell Wall Synthesis (Tipper, D. J., Ed.), pp. 133-66. Pergamon Press, Oxford.
14. Wallas, C. H. & Strominger, J. L. (1963). Ristocetins, inhibitors of cell wall synthesis in Staphylococcus aureus. Journal of Biological Chemistry 238, 2264-6.
15. Tomasz, A. & Waks, S. (1975). Mechanism of action of penicillin: triggering of the pneumococcal autolytic enzyme by inhibitors of cell wall synthesis. Proceedings of the National Academy of Sciences, USA 72, 4162-6.
16. Mattsson, E., Van Dijk, H., Verhoef, J. et al. (1996). Supernatants from Staphylococcus epidermidis grown in the presence of different antibiotics induce differential release of tumor necrosis factor alpha from human monocytes. Infection and Immunity 10, 4351-5.