Relationship between morphological changes and endotoxin release induced by carbapenems in Pseudomonas aeruginosa

Journal of Medical Microbiology

Volumn 48, Issue 3, 1999, Pages 309-315

  Horii, Toshinobu ^a   Ichiyama, Satoshi ^b   Ohta, Michio ^a   Kobayashi, Miya ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIAPENEM; CARBAPENEM DERIVATIVE; ENDOTOXIN; IMIPENEM; MEROPENEM; PANIPENEM;

ARTICLE; BACTERIAL CELL WALL; CELL SHAPE; CELL STRUCTURE; CONTROLLED STUDY; CYTOLYSIS; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA;

PSEUDOMONAS AERUGINOSA;

EID: 0032778679     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/00222615-48-3-309     Document Type: Article

References (22)

1. Shenep JL, Flynn PM, Barrett FF et al. Serial quantitation of endotoxemia and bacteremia during therapy for Gram-negative bacterial sepsis. J Infect Dis 1988; 157: 565-568.
2. Hurley JC, Antibiotic-induced release of endotoxin: a reappraisal. Clin Infect Dis 1992; 15: 840-854.
3. Leibovici L. Drucker M, Konigsberger H et al. Septic shock in bacteremic patients: risk factors. Features and prognosis. Scand J Infect Dis 1997; 29: 71-75.
4. Mock CN, Jurkovich GJ, Dries D, Maier RV. The clinical significance of endotoxin released by antibiotics: what is the evidence? J Endotoxin Res 1996; 3: 253-259.
5. Morrison DC, Bucklin SE. Evidence for antibiotic-mediated endotoxin release as a contributing factor to lethality in experimental Gram-negative sepsis. Scand J Infect Dis 1996; Suppl 101: 3-8.
6. Arditi M, Abies L, Yogev R. Cerebrospinal fluid endotoxin levels in children with H. influence meningitis before and after administration of intravenous ceftriaxone. J Infect Dis 1989; 160: 1005-1011.
7. Hurley JC, Louis WJ, Tosolini FA, Carlin JB. Antibiotic-induced release of endotoxin in chronically bacteriuric patients. Antimicrob Agents Chemother 1991; 35: 2388-2394.
8. Dofferhoff ASM, Nijland JH, de Vries-Hospers HG, Mulder POM, Weits J, Bom VJJ, Effects of different types and combinations of antimicrobial agents on endotoxin release from Gram-negative bacteria: an in-vitro and in-vivo study. Scand J Infect Dis 1991; 23: 745-754.
9. Prins JM, van Agtmael MA, Kuijper EDJ, van Deventer SJH, Speclman P. Antibiotic-induced endotoxin release in patients with gram-negative urosepsis: a double-blind study comparing imipenem and ceftazidime. J Infect Dis 1995; 172: 886-891.
10. Jackson JJ, Kropp H. β-lactam antibiotic-induced release of free endotoxin: in vitro comparison of penicillin-binding protein (PBP) 2-specific imipenem and PBP 3-specific ceftazidime. J Infect Dis 1992; 165: 1033-1041.
11. Prins JM, van Deventer SJH, Kuijper EJ, Speelman P. Clinical relevance of antibiotic-induced endotoxin release. Antimicrob Agents Chemother 1994; 38: 1211-1218.
12. Eng RHK, Smith SM, Fan-Havard P, Oghara T. Effect of antibiotics on endotoxin release from gram-negative bacteria. Diagn Microbiol Infect Dis 1993; 16: 185-189.
13. Ohya S, Utsui Y, Yajima T et al Microbiological evaluation of panipenem/betamipron, a new parenterally active carbapenem II. Mechanism of antibacterial activity of panipenem. Chemotherapy 1991; 39 Suppl 3: 102-110.
14. Nishino T, Otsuka M, Obana Y et al. In vitro and in vivo antibacterial activity of biapenem, a new carbapenem antibiotic. Chemotherapy 1994; 42 Suppl 4: 64-84.
15. Jackson JJ, Kropp H. Differences in mode of action of β- lactam antibiotics influence morphology, LPS release and in vivo antibiotic efficacy. J Endotoxin Res 1996; 3: 201-218.
16. Sumita Y, Tada E, Nouda H, Okuda T, Fukusawa M. Mode of action of meropenem, a new carbapenem antibiotic. Chemotherapy 1992; 40 (S-1): 90-102.
17. Horii T, Kobayashi M, Sato K, Ichiyama S, Ohta M. An in vitro study of carbapenem-induced morphological changes and endotoxin release in clinical isolates of Grain-negative bacilli. J Antimicrob Chemother 1998; 41: 435-442.
18. Crosby HA, Bion JF, Penn CW, Elliott TSJ. Antibiotic-induced release of endotoxin from bacteria in vitro. J Med Microbiol 1994; 40: 23-30.
19. National Committee for Clinical Laboratory Standards. Methods for dilution antimicrobial susceptibility testing for bacteria that grow aerobically, 2nd edn. Approved Standard M7-A3. Villanova, PA, NCCLS. 1993.
20. Obayashi T, Tamura H, Tanaka S, Ohki M, Takahashi S. Kawai T. Endotoxin-inactivating activity in normal and pathological human blood samples. Infect Immun 1986; 53: 294-297.
21. Dofferhoff ASM, Buys J. The influence of antibiotic-induced filament formation on the release of endotoxin from Gram-negative bacteria. J Endotoxin Res 1996; 3: 187-194.
22. Cadieux JE, Kuzio J, Milazzo FH, Kropinski AM. Spontaneous release of lipopolysaccharide by Pseudomonas aeruginosa. J Bacteriol 1983; 155: 817-825.