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Volumn 32, Issue 3, 1998, Pages 657-664

The scientific basis of drug-drug interactions: Mechanism and preclinical evaluation

Author keywords

Drug drug interactions; Hepatocytes; Human; In vitro systems; Liver

Indexed keywords

DRUG CLEARANCE; DRUG INTERACTION; DRUG MECHANISM; ENZYME METABOLISM; HUMAN; IN VITRO STUDY; LIVER MICROSOME; METABOLIC CLEARANCE RATE; PRIORITY JOURNAL; REVIEW;

EID: 3543017295     PISSN: 00928615     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (7)

References (38)
  • 2
    • 0027118223 scopus 로고
    • Warnings issued on nonsedating antihistamines terfenadine and astemizole
    • PDA. Warnings issued on nonsedating antihistamines terfenadine and astemizole. JAMA. 1992;268:705.
    • (1992) JAMA , vol.268 , pp. 705
  • 4
    • 0027168405 scopus 로고
    • Oxidation of the antihistamine drug terfenadine in human liver microsomes. Role of cytochrome P4503A(4) in N-dealkylation and C-hydroxylation
    • Yun CH, Okerholm A, Guengerich FP. Oxidation of the antihistamine drug terfenadine in human liver microsomes. Role of cytochrome P4503A(4) in N-dealkylation and C-hydroxylation. Drug Metab Disp. 1993;21:403-409.
    • (1993) Drug Metab Disp. , vol.21 , pp. 403-409
    • Yun, C.H.1    Okerholm, A.2    Guengerich, F.P.3
  • 5
    • 0027474601 scopus 로고
    • Mechanism of the cardiotoxic actions of terfenadine
    • Woosley RL, Chen Y, Freiman JP, Gillis RA. Mechanism of the cardiotoxic actions of terfenadine. JAMA. 1993;269:1532-1536.
    • (1993) JAMA , vol.269 , pp. 1532-1536
    • Woosley, R.L.1    Chen, Y.2    Freiman, J.P.3    Gillis, R.A.4
  • 6
    • 0022521713 scopus 로고
    • D'Arcy PR Drug interactions with oral contraceptives
    • D'Arcy PR Drug interactions with oral contraceptives. Drug Intell Clin Pharm. 1986;20:353-362.
    • (1986) Drug Intell Clin Pharm , vol.20 , pp. 353-362
  • 7
    • 0028031172 scopus 로고
    • Clinically significant drug interactions with antituberculosis agents
    • Grange JM, Winstanley PA, Davies PD. Clinically significant drug interactions with antituberculosis agents. Drug Saf. 1994;11:242-251.
    • (1994) Drug Saf. , vol.11 , pp. 242-251
    • Grange, J.M.1    Winstanley, P.A.2    Davies, P.D.3
  • 8
    • 0028567499 scopus 로고
    • Induction and autoinduction properties of rifamycin derivatives: A review of animal and human studies
    • Strolin Benedetti M, Dosiert P Induction and autoinduction properties of rifamycin derivatives: a review of animal and human studies. Environ Health Perspect. 1994;102:101-105.
    • (1994) Environ Health Perspect , vol.102 , pp. 101-105
    • Strolin Benedetti, M.1    Dosiert, P.2
  • 10
    • 0029021932 scopus 로고
    • Rifampicin induction of lidocaine metabolism in cultured human hepatocytes
    • Li AP, Xu L, Rasmussen A, Kaminski DL. Rifampicin induction of lidocaine metabolism in cultured human hepatocytes. J Pharmacol Exp Ther. 1995;274:673-677.
    • (1995) J Pharmacol Exp Ther. , vol.274 , pp. 673-677
    • Li, A.P.1    Xu, L.2    Rasmussen, A.3    Kaminski, D.L.4
  • 11
    • 0030803654 scopus 로고    scopus 로고
    • Applications of primary human hepatocytes in the evaluation of pharmacokinetic drug-drug interactions: Evaluation of model drugs terfenadine and rifampin
    • Li AP, Jurirna-Romet M. Applications of primary human hepatocytes in the evaluation of pharmacokinetic drug-drug interactions: evaluation of model drugs terfenadine and rifampin. Cell Biol Toxicol 1997;13:365-374.
    • (1997) Cell Biol Toxicol , vol.13 , pp. 365-374
    • Li, A.P.1    Jurirna-Romet, M.2
  • 12
    • 0025688510 scopus 로고
    • Metabolism of 17a-ethynylestradiol in humans
    • Guengerich FP. Metabolism of 17a-ethynylestradiol in humans. Life Sci. 1990;47:1981-1988.
    • (1990) Life Sci. , vol.47 , pp. 1981-1988
    • Guengerich, F.P.1
  • 13
    • 0016389725 scopus 로고
    • Rifampicin and the "pill" do not go well together
    • Reimers D, Nocke-Finck L, Breuer H. Rifampicin and the "pill" do not go well together. JAMA. 1974;227:608.
    • (1974) JAMA , vol.227 , pp. 608
    • Reimers, D.1    Nocke-Finck, L.2    Breuer, H.3
  • 14
    • 0021848458 scopus 로고
    • Verapamil-rifampin interaction
    • Barbarash RA. Verapamil-rifampin interaction. Drug Inlell Clin Pharm. 1985;19:559-560.
    • (1985) Drug Inlell Clin Pharm , vol.19 , pp. 559-560
    • Barbarash, R.A.1
  • 15
    • 0029786432 scopus 로고    scopus 로고
    • Differential induction of prehepatic and hepatic metabolism of verapamil by rifampin
    • Fromm MF, Busse D, Kroemer HK, Eichelbaum M. Differential induction of prehepatic and hepatic metabolism of verapamil by rifampin. Hepatology. 1996;24:796-801.
    • (1996) Hepatology , vol.24 , pp. 796-801
    • Fromm, M.F.1    Busse, D.2    Kroemer, H.K.3    Eichelbaum, M.4
  • 16
    • 0026457407 scopus 로고
    • Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction
    • Herbert MF, Roberts JP, Prueksaritanont T, Benet LZ. Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction. Clin Pharmacol Ther. 1992;52:453-457.
    • (1992) Clin Pharmacol Ther. , vol.52 , pp. 453-457
    • Herbert, M.F.1    Roberts, J.P.2    Prueksaritanont, T.3    Benet, L.Z.4
  • 17
    • 0027430886 scopus 로고
    • Therapy of experimental murine burcellosis with streptomycin alone and in combination with ciprofloxacin, doxycycline, and rifampin
    • Lang R, Shasha B, Rubinstein E. Therapy of experimental murine burcellosis with streptomycin alone and in combination with ciprofloxacin, doxycycline, and rifampin. Antimicrob Agents Chemother. 1993;37:2333-2336.
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 2333-2336
    • Lang, R.1    Shasha, B.2    Rubinstein, E.3
  • 19
    • 0028009473 scopus 로고
    • Coadministration of rifampin and itraconazole leads to undetectable levels of serum intraconazole
    • Drayton J, Dickinson G, Rinaldi MG. Coadministration of rifampin and itraconazole leads to undetectable levels of serum intraconazole (letter). Clin Infect Dis. 1994;18:266.
    • (1994) Clin Infect Dis. , vol.18 , pp. 266
    • Drayton, J.1    Dickinson, G.2    Rinaldi, M.G.3
  • 20
    • 0027422106 scopus 로고
    • Time course of the changes in prednisolone pharmacokinetics after coadministration or discontinuation of rifampin
    • Lee KH, Shin JG, Chong WS, Kim S, Lee JS, Jang IJ, Shin SG. Time course of the changes in prednisolone pharmacokinetics after coadministration or discontinuation of rifampin. Eur J Clin Pharmacol. 1993;45:287-289.
    • (1993) Eur J Clin Pharmacol. , vol.45 , pp. 287-289
    • Lee, K.H.1    Shin, J.G.2    Chong, W.S.3    Kim, S.4    Lee, J.S.5    Jang, I.J.6    Shin, S.G.7
  • 23
    • 0028114740 scopus 로고
    • Use of in vitro human metabolism studies in drug development: An industrial perspective
    • Rodrigues AD. Use of in vitro human metabolism studies in drug development: an industrial perspective. Biochem Pharmacol. 1994;48:2147-2156.
    • (1994) Biochem Pharmacol , vol.48 , pp. 2147-2156
    • Rodrigues, A.D.1
  • 25
    • 0001714139 scopus 로고
    • Primary hepatocyte culture as an in vitro toxicologicai system
    • Shayne Gad, ed. New York, NY: Raven Press
    • Li AP. Primary hepatocyte culture as an in vitro toxicologicai system. In: Shayne Gad, ed. In Vitro Toxicology. New York, NY: Raven Press; 1994:195-220.
    • (1994) In Vitro Toxicology , pp. 195-220
    • Li, A.P.1
  • 26
    • 84993828290 scopus 로고    scopus 로고
    • Primary hepatocyte cultures as an experimental model for the evaluation of pharmacokinetic drug-drug interactions
    • Albert P. Li, ed. San Diego, CA; Academic Press
    • Li AP. Primary hepatocyte cultures as an experimental model for the evaluation of pharmacokinetic drug-drug interactions. In: Albert P. Li, ed. Drug-drug interactions: scientific and regulatory perspectives. San Diego, CA; Academic Press; 1997:103-130.
    • (1997) Drug-drug Interactions: Scientific and Regulatory Perspectives , pp. 103-130
    • Li, A.P.1
  • 27
    • 0030726508 scopus 로고    scopus 로고
    • Preclinical evaluation of drug-drug interactions: Present status of the application of primary human hepatocytes in the evaluation of cytochrome P450 incution
    • Li AP, Maurel P, Gomez-Lechon MJ, Cheng LC, Jurima-Romet M. Preclinical evaluation of drug-drug interactions: present status of the application of primary human hepatocytes in the evaluation of cytochrome P450 incution. Chemico-biological Interactions. 1998;107:5-16.
    • (1998) Chemico-biological Interactions , vol.107 , pp. 5-16
    • Li, A.P.1    Maurel, P.2    Gomez-Lechon, M.J.3    Cheng, L.C.4    Jurima-Romet, M.5
  • 28
    • 0019313649 scopus 로고
    • A new instrument for the rapid preparation of tissue slices
    • Krumdieck CL, Dos Santos JE, Ho KJ. A new instrument for the rapid preparation of tissue slices. Anal Biochem. 1980;104:118-123.
    • (1980) Anal Biochem , vol.104 , pp. 118-123
    • Krumdieck, C.L.1    Dos Santos, J.E.2    Ho, K.J.3
  • 30
    • 0026443864 scopus 로고
    • Cyclosporin A metabolism in human liver, kidney, and intestine slices. Comparison to rat and dog slices and human cell lines
    • Vickers AEM, Fischer V, Connors S, Fisher RL, Baldeck JP, Maurer G, Brendel K. Cyclosporin A metabolism in human liver, kidney, and intestine slices. Comparison to rat and dog slices and human cell lines. Drug Metab Dispos. 1992;20:802-809.
    • (1992) Drug Metab Dispos. , vol.20 , pp. 802-809
    • Vickers, A.E.M.1    Fischer, V.2    Connors, S.3    Fisher, R.L.4    Baldeck, J.P.5    Maurer, G.6    Brendel, K.7
  • 31
    • 0026096161 scopus 로고
    • A metabolically competent cell line expressing five cDNAs encoding procarcinogen-activating enzymes: Applications to mutagenicity testing
    • Crespi CL, Gonzalez FJ, Steimel DT, Turner TR, Gelboin HV, Penman BW, Langenbach R. A metabolically competent cell line expressing five cDNAs encoding procarcinogen-activating enzymes: applications to mutagenicity testing. Chem Res Toxicol. 1991;4:566-572.
    • (1991) Chem Res Toxicol. , vol.4 , pp. 566-572
    • Crespi, C.L.1    Gonzalez, F.J.2    Steimel, D.T.3    Turner, T.R.4    Gelboin, H.V.5    Penman, B.W.6    Langenbach, R.7
  • 32
    • 0027491376 scopus 로고
    • Human cell lines, derived from AHH-1 TK-+/- Human lymphoblasts, genetically engineered for expression of cytochromes P450
    • Crespi CL, Langenbach R, Penman BW. Human cell lines, derived from AHH-1 TK-+/- human lymphoblasts, genetically engineered for expression of cytochromes P450. Toxicol 1993;82:89-104.
    • (1993) Toxicol , vol.82 , pp. 89-104
    • Crespi, C.L.1    Langenbach, R.2    Penman, B.W.3
  • 33
    • 0027223881 scopus 로고
    • Expression of modified human cytochrome P450 3A4 in Escherichia coli and purification and reconstitution of the enzyme
    • Gillam EMJ, Baba T, Kim BR, Ohmori S, Guengerich FP. Expression of modified human cytochrome P450 3A4 in Escherichia coli and purification and reconstitution of the enzyme. Arch Biochem Biophys. 1993;305:123-131.
    • (1993) Arch Biochem Biophys , vol.305 , pp. 123-131
    • Gillam, E.M.J.1    Baba, T.2    Kim, B.R.3    Ohmori, S.4    Guengerich, F.P.5
  • 36
    • 0029584276 scopus 로고
    • Substrates of human hepatic cytochrome P4503A4
    • Li AP, Kaminski DL, Rasmussen A. Substrates of human hepatic cytochrome P4503A4. Toxicol. 1995a;104:1-8.
    • (1995) Toxicol , vol.104 , pp. 1-8
    • Li, A.P.1    Kaminski, D.L.2    Rasmussen, A.3
  • 38
    • 0030483808 scopus 로고    scopus 로고
    • Metabolism of terfenadine and its inhibition in primary human and rat hepatocytes and HepG2 cells
    • Jurima-Romet M, Huang HS, Beck DJ, Li AP. Metabolism of terfenadine and its inhibition in primary human and rat hepatocytes and HepG2 cells. Toxicol in Vitro. 10:655-663.
    • Toxicol in Vitro , vol.10 , pp. 655-663
    • Jurima-Romet, M.1    Huang, H.S.2    Beck, D.J.3    Li, A.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.